Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Sergei L Kosakovsky Pond"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0291688 (2024)
The evolution of lineage-specific gene families remains poorly studied across the eukaryotic tree of life, with most analyses focusing on the recent evolution of de novo genes in model species. Here we explore the origins of lineage-specific genes in
Externí odkaz:
https://doaj.org/article/b0b93a225eb448ce956e98796f0abc2f
Autor:
Seth C Inzaule, Mark J Siedner, Susan J Little, Santiago Avila-Rios, Alisen Ayitewala, Ronald J Bosch, Vincent Calvez, Francesca Ceccherini-Silberstein, Charlotte Charpentier, Diane Descamps, Susan H Eshleman, Joseph Fokam, Lisa M Frenkel, Ravindra K Gupta, John P A Ioannidis, Pontiano Kaleebu, Rami Kantor, Seble G Kassaye, Sergei L Kosakovsky Pond, Vinie Kouamou, Roger D Kouyos, Daniel R Kuritzkes, Richard Lessells, Anne-Genevieve Marcelin, Lawrence Mbuagbaw, Brian Minalga, Nicaise Ndembi, Richard A Neher, Roger Paredes, Deenan Pillay, Elliot G Raizes, Soo-Yon Rhee, Douglas D Richman, Kiat Ruxrungtham, Pardis C Sabeti, Jonathan M Schapiro, Sunee Sirivichayakul, Kim Steegen, Wataru Sugiura, Gert U van Zyl, Anne-Mieke Vandamme, Annemarie M J Wensing, Joel O Wertheim, Huldrych F Gunthard, Michael R Jordan, Robert W Shafer
Publikováno v:
PLoS Medicine, Vol 20, Iss 9, p e1004293 (2023)
• Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug resistance leads to the requirement for antiretroviral drugs that
Externí odkaz:
https://doaj.org/article/c16a34440b374c53938659e86b679144
Autor:
Collin Joyce, Sasha Murrell, Ben Murrell, Oluwarotimi Omorodion, Lorena S Ver, Nancy Carrico, Raiza Bastidas, Rebecca Nedellec, Michael Bick, Jordan Woehl, Fangzhu Zhao, Alison Burns, Shawn Barman, Michael Appel, Alejandra Ramos, Lalinda Wickramasinghe, Kemal Eren, Thomas Vollbrecht, Davey M Smith, Sergei L Kosakovsky Pond, Ryan McBride, Charli Worth, Facundo Batista, Devin Sok, IAVI Protocol C Investigators & The IAVI African HIV Research Network, Pascal Poignard, Bryan Briney, Ian A Wilson, Elise Landais, Dennis R Burton
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011416 (2023)
Vaccination strategies aimed at maturing broadly neutralizing antibodies (bnAbs) from naïve precursors are hindered by unusual features that characterize these Abs, including insertions and deletions (indels). Longitudinal studies of natural HIV inf
Externí odkaz:
https://doaj.org/article/f3290d1bda334e7a969850f0b8f21e00
Autor:
Mario C Raviglione, Sudhir Kumar, Gianvincenzo Zuccotti, Marta Canuti, Silvia Bianchi, Otto Kolbl, Sergei L Kosakovsky Pond, Maria Gori, Clara Fappani, Daniela Colzani, Elisa Borghi, Elisabetta Tanzi, Antonella Amendola
Publikováno v:
BMJ Global Health, Vol 7, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/e6a20fd2f18f4590aa475f850b3adbd5
Autor:
Alexander G Lucaci, Jordan D Zehr, Stephen D Shank, Dave Bouvier, Alexander Ostrovsky, Han Mei, Anton Nekrutenko, Darren P Martin, Sergei L Kosakovsky Pond
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0275623 (2022)
An important unmet need revealed by the COVID-19 pandemic is the near-real-time identification of potentially fitness-altering mutations within rapidly growing SARS-CoV-2 lineages. Although powerful molecular sequence analysis methods are available t
Externí odkaz:
https://doaj.org/article/bca1a56d05294988afd66598cded39bb
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0261045 (2022)
As novel SARS-CoV-2 variants with different patterns of spike protein mutations have emerged, the susceptibility of these variants to neutralization by antibodies has been rapidly assessed. However, neutralization data are generated using different a
Externí odkaz:
https://doaj.org/article/6a12b3be12da44eabbc2dc61b0e1a590
Autor:
Oscar A MacLean, Spyros Lytras, Steven Weaver, Joshua B Singer, Maciej F Boni, Philippe Lemey, Sergei L Kosakovsky Pond, David L Robertson
Publikováno v:
PLoS Biology, Vol 19, Iss 3, p e3001115 (2021)
Virus host shifts are generally associated with novel adaptations to exploit the cells of the new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has apparently required little to no significant adap
Externí odkaz:
https://doaj.org/article/69d3f0a61330400a8ff75a6037d7b399
Autor:
Alexander G Lucaci, Sadie R Wisotsky, Stephen D Shank, Steven Weaver, Sergei L Kosakovsky Pond
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248337 (2021)
Despite many attempts to introduce evolutionary models that permit substitutions to instantly alter more than one nucleotide in a codon, the prevailing wisdom remains that such changes are rare and generally negligible or are reflective of non-biolog
Externí odkaz:
https://doaj.org/article/8c1c63c09e00483a8808e2e2339075da
Autor:
Sayaka Miura, Koichiro Tamura, Qiqing Tao, Louise A Huuki, Sergei L Kosakovsky Pond, Jessica Priest, Jiamin Deng, Sudhir Kumar
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 1, p e1007046 (2020)
Pathogen timetrees are phylogenies scaled to time. They reveal the temporal history of a pathogen spread through the populations as captured in the evolutionary history of strains. These timetrees are inferred by using molecular sequences of pathogen
Externí odkaz:
https://doaj.org/article/a64b8cc22e1849b9a77bcb066896e6a2
Autor:
Philip L Tzou, Sergei L Kosakovsky Pond, Santiago Avila-Rios, Susan P Holmes, Rami Kantor, Robert W Shafer
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0225352 (2020)
IntroductionAt low mutation-detection thresholds, next generation sequencing (NGS) for HIV-1 genotypic resistance testing is susceptible to artifactual detection of mutations arising from PCR error and APOBEC-mediated G-to-A hypermutation.MethodsWe a
Externí odkaz:
https://doaj.org/article/922bfe8898a34209a3e2a7783bf3025d