Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sergei Chuikov"'
Autor:
Qin Wang, Sergei Chuikov, Sophina Taitano, Qi Wu, Arjun Rastogi, Samuel J. Tuck, Joseph M. Corey, Steven K. Lundy, Yang Mao-Draayer
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13885-13907 (2015)
Multiple sclerosis (MS) is the most common multifocal inflammatory demyelinating disease of the central nervous system (CNS). Due to the progressive neurodegenerative nature of MS, developing treatments that exhibit direct neuroprotective effects are
Externí odkaz:
https://doaj.org/article/b8578c60e2e04bc7a34ecdee04e188a3
Autor:
Sergei Chuikov, Steven K. Lundy, Joseph M. Corey, Qi Wu, Yang Mao-Draayer, Qin Wang, Sophina H. Taitano, Arjun Rastogi, Samuel J. Tuck
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13885-13907 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 6
Pages 13885-13907
International Journal of Molecular Sciences
Volume 16
Issue 6
Pages 13885-13907
Multiple sclerosis (MS) is the most common multifocal inflammatory demyelinating disease of the central nervous system (CNS). Due to the progressive neurodegenerative nature of MS, developing treatments that exhibit direct neuroprotective effects are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a642cb6961aabd4900aafd912b40f4
http://www.mdpi.com/1422-0067/16/6/13885
http://www.mdpi.com/1422-0067/16/6/13885
Publikováno v:
Nature cell biology
To better understand the mechanisms that regulate stem cell identity and function, we sought to identify genes that are preferentially expressed by stem cells and critical for their function in multiple tissues. Prdm16 is a transcription factor that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510e3db5065d5747e67dcccd6c9990c5
http://europepmc.org/articles/PMC2948585
http://europepmc.org/articles/PMC2948585
Autor:
Thomas Jenuwein, Jean Dorsey, Jing Huang, Danny Reinberg, Sergei Chuikov, Shelley L. Berger, Xinyue Zhang
Publikováno v:
The Journal of Biological Chemistry
The tumor suppressor p53 is regulated by numerous post-translational modifications. Lysine methylation has recently emerged as a key post-translational modification that alters the activity of p53. Here, we describe a novel lysine methylation site in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b9f684d3c4a98973906978a1c3ebad
https://doi.org/10.1074/jbc.m109.062588
https://doi.org/10.1074/jbc.m109.062588
Autor:
Judd C. Rice, Janis Werner, Pablo Valenzuela, Ruth Steward, John T. Lis, Kavitha Sarma, Hediye Erdjument-Bromage, Kenichi Nishioka, Paul Tempst, Danny Reinberg, Yanming Wang, C. David Allis, Sergei Chuikov
Publikováno v:
Molecular Cell. 9(6):1201-1213
We have purified a human histone H4 lysine 20 methyltransferase and cloned the encoding gene, PR/SET07. A mutation in Drosophila pr-set7 is lethal: second instar larval death coincides with the loss of H4 lysine 20 methylation, indicating a fundament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fcf2262f459c1f906ba5f3c536c1f8
Autor:
Daniel Libutti, Hui Ge, Achim Weber, Xin Wei Wang, Sergei Chuikov, Curtis C. Harris, Danny Reinberg, Ronald C. Conaway, Joan W. Conaway, Juhong Liu, David Levens, Sasha Akoulitchev
Publikováno v:
Cell. 104:353-363
Inherited mutations of the TFIIH helicase subunits xeroderma pigmentosum (XP) B or XPD yield overlapping DNA repair and transcription syndromes. The high risk of cancer in these patients is not fully explained by the repair defect. The transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d4c30f9549c10fa2f160c5bfea32ae
https://doi.org/10.1016/s0092-8674(01)00223-9
https://doi.org/10.1016/s0092-8674(01)00223-9
Autor:
Kristine McKinney, Neil Justin, Steven J. Gamblin, Paul Tempst, Julia K. Kurash, Gleb S. Ivanov, Sergei Chuikov, Danny Reinberg, Carol Prives, Nickolai A. Barlev, Bing Xiao, Jonathan R. Wilson
Publikováno v:
Nature. 432(7015)
p53 is a tumour suppressor that regulates the cellular response to genotoxic stresses. p53 is a short-lived protein and its activity is regulated mostly by stabilization via different post-translational modifications. Here we report a novel mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854432ce2b76894384e2d010b2c61153
https://pubmed.ncbi.nlm.nih.gov/15525938
https://pubmed.ncbi.nlm.nih.gov/15525938
Autor:
C. David Allis, Sergei Chuikov, Hediye Erdjument-Bromage, Paul Tempst, Danny Reinberg, Kavitha Sarma, Kenichi Nishioka
A novel histone methyltransferase, termed Set9, was isolated from human cells. Set9 contains a SET domain, but lacks the pre- and post-SET domains. Set9 methylates specifically lysine 4 (K4) of histone H3 (H3-K4) and potentiates transcription activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787da65a569a52439490720143a0e36e
https://europepmc.org/articles/PMC155346/
https://europepmc.org/articles/PMC155346/
Publikováno v:
Nature. 407(6800)
The mammalian cyclin-dependent kinase 8 (cdk8) gene has been linked with a subset of acute lymphoblastic leukaemias, and its corresponding protein has been functionally implicated in regulation of transcription. Mammalian cdk8 and cyclin C, and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a0c0ddebd15ab08cca8b6fb00d0071
https://pubmed.ncbi.nlm.nih.gov/10993082
https://pubmed.ncbi.nlm.nih.gov/10993082