Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Sergei, Kopanchuk"'
Autor:
Mart Ernits, Olavi Reinsalu, Naresh Yandrapalli, Sergei Kopanchuk, Ehsan Moradpur-Tari, Immanuel Sanka, Ott Scheler, Ago Rinken, Reet Kurg, Andreas Kyritsakis, Veikko Linko, Veronika Zadin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract In advanced drug delivery, versatile liposomal formulations are commonly employed for safer and more accurate therapies. Here we report a method that allows a straightforward production of synthetic monodisperse (~ 100 μm) giant unilamellar
Externí odkaz:
https://doaj.org/article/d3722b7656734c66a34061ea096fff76
Autor:
Jurgita Matulienė, Gediminas Žvinys, Vytautas Petrauskas, Agnė Kvietkauskaitė, Audrius Zakšauskas, Kirill Shubin, Asta Zubrienė, Lina Baranauskienė, Lina Kačenauskaitė, Sergei Kopanchuk, Santa Veiksina, Vaida Paketurytė-Latvė, Joana Smirnovienė, Vaida Juozapaitienė, Aurelija Mickevičiūtė, Vilma Michailovienė, Jelena Jachno, Dovilė Stravinskienė, Aistė Sližienė, Agnė Petrošiūtė, Holger M. Becker, Justina Kazokaitė-Adomaitienė, Ala Yaromina, Edita Čapkauskaitė, Ago Rinken, Virginija Dudutienė, Ludwig J Dubois, Daumantas Matulis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-25 (2022)
Abstract Numerous human cancers, especially hypoxic solid tumors, express carbonic anhydrase IX (CAIX), a transmembrane protein with its catalytic domain located in the extracellular space. CAIX acidifies the tumor microenvironment, promotes metastas
Externí odkaz:
https://doaj.org/article/37ebb5e55c0a4123a7c8f686b66ab087
Autor:
Getnet Midekessa, Kasun Godakumara, James Ord, Janeli Viil, Freddy Lättekivi, Keerthie Dissanayake, Sergei Kopanchuk, Ago Rinken, Aneta Andronowska, Sourav Bhattacharjee, Toonika Rinken, Alireza Fazeli
Publikováno v:
ACS Omega, Vol 5, Iss 27, Pp 16701-16710 (2020)
Externí odkaz:
https://doaj.org/article/a0b98b62b41246a5a31d21bf20bdfc8e
Autor:
Robin Ehrminger, Kairi Kivirand, Sergei Kopanchuk, Mart Min, Ago Rinken, Toonika Rinken, Tavo Romann
Publikováno v:
Proceedings of the Estonian Academy of Sciences, Vol 69, Iss 1, Pp 27-34 (2020)
Quality of bioactive surface is crucial for achieving the required sensitivity and selectivity of biosensing systems. Numerous methods are available for the characterization of metal-coated surfaces, but only a few to test the efficacy of biomaterial
Externí odkaz:
https://doaj.org/article/1656dfb3df134253910278b1cd99069f
Autor:
Sergei Kopanchuk, Edijs Vavers, Santa Veiksina, Kadri Ligi, Liga Zvejniece, Maija Dambrova, Ago Rinken
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268563 (2022)
Sigma-1 receptor (Sig1R) is an endoplasmic reticulum (ER)-related membrane protein, that forms heteromers with other cellular proteins. As the mechanism of action of this chaperone protein remains unclear, the aim of the present study was to detect a
Externí odkaz:
https://doaj.org/article/d7b5711de27e439cbc690a993924147d
Autor:
Prakash Lingasamy, Kristina Põšnograjeva, Sergei Kopanchuk, Allan Tobi, Ago Rinken, Ignacio J. General, Eliana K. Asciutto, Tambet Teesalu
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 1998 (2021)
Tumor extracellular matrix (ECM) is a high-capacity target for the precision delivery of affinity ligand-guided drugs and imaging agents. Recently, we developed a PL1 peptide (sequence: PPRRGLIKLKTS) for systemic targeting of malignant ECM. Here, we
Externí odkaz:
https://doaj.org/article/35efdae0d2af490fa00a8f9f9b757703
Autor:
Olivier E. Nonga, Darja Lavogina, Erki Enkvist, Katrin Kestav, Apirat Chaikuad, Sarah E. Dixon-Clarke, Alex N. Bullock, Sergei Kopanchuk, Taavi Ivan, Ramesh Ekambaram, Kaido Viht, Stefan Knapp, Asko Uri
Publikováno v:
Molecules, Vol 26, Iss 14, p 4353 (2021)
We performed an X-ray crystallographic study of complexes of protein kinase PIM-1 with three inhibitors comprising an adenosine mimetic moiety, a linker, and a peptide-mimetic (d-Arg)6 fragment. Guided by the structural models, simplified chemical st
Externí odkaz:
https://doaj.org/article/a3a8d1a0bd22472d8e0cc873fa4e2ef8
Publikováno v:
BioTechniques, Vol 63, Iss 4, Pp 161-168 (2017)
Measurement of virus concentration is essential for effective virus-based transfection technologies. Here, we describe a user-friendly, image-based cell-size estimation (ICSE) assay for baculovirus quantification that relies on automated determinatio
Externí odkaz:
https://doaj.org/article/c39bd0e00b224458b1b532124e15e6e2
Autor:
Christoph Müller, Jakob Gleixner, Maris-Johanna Tahk, Sergei Kopanchuk, Tõnis Laasfeld, Michael Weinhart, Dieter Schollmeyer, Martin U. Betschart, Steffen Lüdeke, Pierre Koch, Ago Rinken, Max Keller
Publikováno v:
Journal of Medicinal Chemistry. 65:4832-4853
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c03626c040dc6327a050067f61e56a44
https://doi.org/10.1021/acs.jmedchem.1c02033
https://doi.org/10.1021/acs.jmedchem.1c02033
Autor:
Külli Samuel, Sergei Kopanchuk, Riikka K Arffman, Sergo Kasvandik, Masuma Khatun, Agne Velthut-Meikas, Darja Lavogina, Andres Salumets, Ago Rinken, Artjom Stepanjuk, Maire Peters, Asko Uri, Terhi Piltonen, Freddy Lättekivi, Erki Enkvist, Kaido Viht
Publikováno v:
Human Reproduction
STUDY QUESTION Can a combination of the focussed protein kinase assays and a wide-scale proteomic screen pinpoint novel, clinically relevant players in decidualization in vitro and in vivo? SUMMARY ANSWER Rho-dependent protein kinase (ROCK) activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43556732a2aec8f7c3ba9807757b5103
https://doi.org/10.1093/humrep/deab161
https://doi.org/10.1093/humrep/deab161