Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Serge Nataf"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3803 (2024)
The clinical severity of multiple sclerosis (MS), an autoimmune disorder of the central nervous system, is thought to be determined by environmental and genetic factors that have not yet been identified. In a recent genome-wide association study (GWA
Externí odkaz:
https://doaj.org/article/4d0e63910d0348eb806291f97c8a10a4
Autor:
Serge Nataf
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1596 (2023)
In MS patients with a progressive form of the disease, the slow deterioration of neurological functions is thought to result from a combination of neuronal cell death, axonal damages and synaptic dysfunctions [...]
Externí odkaz:
https://doaj.org/article/0ef2e2f61fb64a66a6243c83c588e1db
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14993 (2022)
In a substantial share of patients suffering from multiple sclerosis (MS), neurological functions slowly deteriorate despite a lack of radiological activity. Such a silent progression, observed in either relapsing-remitting or progressive forms of MS
Externí odkaz:
https://doaj.org/article/f4e070cceb3e4838b7544b5410a20fc3
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/a69b61117b874710a0fa469b330655e9
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
There is circumstantial evidence that, under neurodegenerative conditions, peptides deriving from aggregated or misfolded specific proteins elicit adaptive immune responses. On another hand, several genes involved in familial forms of neurodegenerati
Externí odkaz:
https://doaj.org/article/96580028128a4c1fb30e60a0b35c65b9
Autor:
Serge Nataf, Laurent Pays
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10440 (2021)
For a yet unknown reason, a substantial share of patients suffering from COVID-19 develop long-lasting neuropsychiatric symptoms ranging from cognitive deficits to mood disorders and/or an extreme fatigue. We previously reported that in non-neural ce
Externí odkaz:
https://doaj.org/article/7f488623650d47d99b0ca62d67c584fd
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Social behavior and neuronal connectivity in rodents have been shown to be shaped by the prototypical T lymphocyte-derived pro-inflammatory cytokine Interferon-gamma (IFNγ). It has also been demonstrated that STAT1 (Signal Transducer And Activator O
Externí odkaz:
https://doaj.org/article/c607eb397d0d4c2cb0a79c90fbd6fc28
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6956 (2020)
Severe burn injuries remain a major health problem due to high rates of mortality, residual morbidity, and/or aesthetic damages. To find new therapies aimed at promoting a harmonious healing of skin burns, it is important to develop models which take
Externí odkaz:
https://doaj.org/article/b794be7598164749a35215a5885556dd
Autor:
Olivia Gross-Amat, Marine Guillen, Jean-Pascal Gimeno, Michel Salzet, Nicolas Lebonvallet, Laurent Misery, Céline Auxenfans, Serge Nataf
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4648 (2020)
Although sulfur-rich thermal waters have ancestrally been used in the context of dermatological conditions, a global mapping of the molecular effects exerted by H2S on human keratinocytes is still lacking. To fill this knowledge gap, we subjected cul
Externí odkaz:
https://doaj.org/article/c59ac0cd5fc945bf95404a5ea4bd543d
Autor:
Serge Nataf
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1035 (2020)
The role exerted by Aquaporin 4 (AQP4) as a regulator of astrocyte immune functions has been poorly explored. A recent report demonstrates that under neuroinflammatory conditions, the expression of Aqp4 on murine astrocytes is mandatory for the effec
Externí odkaz:
https://doaj.org/article/f959fe250d8a4bb7bbe8539295f2c971