Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Serge Moreau"'
Autor:
Eric Dausse, Serge Moreau, Isabelle Lebars, Sonia Da Rocha, Laurent Azéma, Jean-Jacques Toulmé
Publikováno v:
Médecine Nucléaire. 31:478-484
Resume Les aptameres sont des oligonucleotides, generalement ARN ou ADN, identifies dans des banques contenant jusqu’a 1015 sequences differentes, par une methode combinatoire de selection in vitro appelee systematic evolution of ligands by exponan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7473e0ce5318e17fdc98b9fc34abbbb9
https://doi.org/10.1016/j.mednuc.2007.07.009
https://doi.org/10.1016/j.mednuc.2007.07.009
Publikováno v:
Canadian Journal of Chemistry. 84:854-858
A large increase in the melting temperature of complementary oligonucleotides was obtained through the conjugation of terpyridine ligands at their nearby 5′ or 3′ ends and the addition of stoichiometric amounts of various transition metals. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d43a646d8463f4a7138919503bfe0f8
https://doi.org/10.1139/v06-080
https://doi.org/10.1139/v06-080
Publikováno v:
European Journal of Organic Chemistry. 2003:1022-1028
Two complementary oligonucleotides were conjugated with terpyridine ligands at their nearby 5′- and 3′-ends. Addition of a stoichiometric amount of a transition metal (Zn2+, Fe2+) resulted in a large increase in the melting temperature of the dup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4369d1ca0734cc28f6df14e095dc13e8
https://doi.org/10.1002/ejoc.200390143
https://doi.org/10.1002/ejoc.200390143
Publikováno v:
Tetrahedron. 58:7975-7982
Short nucleic acid hairpins (one or two base-pair stems) were strongly stabilized by simple chemical modifications. Non-nucleosidic pyrene or naphtalene diimide derivatives were appended at both 3′ and 5′ nearby ends of 2′-OMe RNA hairpins, yie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e99955611dc311a8b3ad42104007d3
https://doi.org/10.1016/s0040-4020(02)00876-1
https://doi.org/10.1016/s0040-4020(02)00876-1
Autor:
Joseph Vercauteren, Jean-Michel Mérillon, Jean-Pierre Monti, Serge Moreau, Tristan Richard, Sarah Vergé, Alain Nurich
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1571:89-101
Polyphenols (tannins) are known for their high propensity to precipitate proteins. They bind most strongly to proteins with a high proline content. Understanding the mechanism of this association is of prime interest because this interaction might in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3f2dfdb7a678c2ad90a351210d272f
https://doi.org/10.1016/s0304-4165(02)00183-6
https://doi.org/10.1016/s0304-4165(02)00183-6
Autor:
Joseph Vercauteren, Jean-Claude Promé, Tristan Richard, Jean-Pierre Monti, Sarah Vergé, Serge Moreau, Suzanne Richelme-David
Publikováno v:
Tetrahedron Letters. 43:2363-2366
Non-covalent complexes for a tannin–protein interaction model have been analyzed by mass spectrometry. The model is the polyphenol penta- O -galloyl- d -glucopyranose (PGG), a representative member of the hydrolysable tannin family and the nonapept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0e81e2a94c85f2b80559a16a93826b9
https://doi.org/10.1016/s0040-4039(02)00255-1
https://doi.org/10.1016/s0040-4039(02)00255-1
Publikováno v:
Antisense and Nucleic Acid Drug Development. 11:301-315
The untranslated 5' leader region of the human immunodeficiency virus type 1 (HIV-1) RNA plays an essential role in retroviral replication. It is the first retrotranscribed RNA region, primed from a cellular tRNALys3 partially annealed to the HIV-1 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beae5cb5c258c44e40f39230b669b485
https://doi.org/10.1089/108729001753231687
https://doi.org/10.1089/108729001753231687
Publikováno v:
Scopus-Elsevier
We developed a new fluorescent analog of cytosine, the 4-amino-1H-benzo[g]quinazoline-2-one, which constitute a probe sensitive to pH. The 2'-O-Me ribonucleoside derivative of this heterocycle was synthesized and exhibited a fluorescence emission cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccaf1fb3d624528b1a4f147719099c9a
https://doi.org/10.1093/nar/28.15.2977
https://doi.org/10.1093/nar/28.15.2977
Autor:
Frédéric Godde, Jean-Jacques Toulmé, Alan G. Weeds, Serge Moreau, Michael J. Gait, Andrey A. Arzumanov
Publikováno v:
Helvetica Chimica Acta. 83:1424-1436
The Tat protein is an essential trans-activator of HIV gene expression. It interacts with its RNA recognition sequence, the trans-activation responsive region TAR, as well as cellular factors. These interactions are potential targets for drug discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0daaea43fdc3a60d51dc00f1fcc4a5fd
https://doi.org/10.1002/1522-2675(20000705)83:7<1424::aid-hlca1424>3.0.co
https://doi.org/10.1002/1522-2675(20000705)83:7<1424::aid-hlca1424>3.0.co
Publikováno v:
Scopus-Elsevier
Benzo[g]quinazoline-2,4-(1H,3H)-dione (BgQ), a fluorescent thymine analog, was incorporated into an oligopyrimidine (III) able to give rise to a triple-stranded structure by clamping a purine 11-mer (I). The formation of the I-III complex resulted in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e002b5bbcb3b847edc9010cf026d1a25
https://doi.org/10.1089/oli.1.1998.8.469
https://doi.org/10.1089/oli.1.1998.8.469