Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Serge M Candéias"'
1
Akademický článek
Sex- and age-specific aspects of human peripheral T-cell dynamics
Autor: Justyna Mika, Kengo Yoshida, Yoichiro Kusunoki, Serge M. Candéias, Joanna Polanska
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
BackgroundThe diversity of the antigenic T cell receptor (TCR) repertoire clonally expressed on T lymphocytes is a key element of the adaptive immune system protective functions. A decline in diversity in the older adults is associated with health de
Externí odkaz: https://doaj.org/article/16e5346e67924706a565964b02f5079c
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2
Akademický článek
Label-Free Direct Mass Spectrometry Analysis of the Bystander Effects Induced in Chondrocytes by Chondrosarcoma Cells Irradiated with X-rays and Carbon Ions
Autor: Antoine Gilbert, Valentin Payet, Benoît Bernay, Elisabeth Chartier-Garcia, Isabelle Testard, Serge M. Candéias, François Chevalier
Publikováno v: Frontiers in Bioscience-Landmark, Vol 27, Iss 9, p 277 (2022)
Background: Radiation-induced bystander effects are induced changes in cells that were not themselves directly irradiated but were in the vicinity of a radiation path. Such effects, which occur in the microenvironment of an irradiated tumor, remain p
Externí odkaz: https://doaj.org/article/df67c4c8ae3540b0aecb57a0f7e17234
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3
Bystander signals from low- and high-dose irradiated human primary fibroblasts and keratinocytes modulate the inflammatory response of peripheral blood mononuclear cells
Autor: Isabelle Testard, Elizabeth Garcia-Chartier, Amani Issa, Véronique Collin-Faure, Catherine Aude-Garcia, Serge M Candéias
Publikováno v: Journal of Radiation Research
Journal of Radiation Research, In press, ⟨10.1093/jrr/rrac094⟩
Irradiated cells can propagate signals to neighboring cells. Manifestations of these so-called bystander effects (BEs) are thought to be relatively more important after exposure to low- vs high-dose radiation and can be mediated via the release of se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29983bea4e2c19906d040036e5424670
https://doi.org/10.1093/jrr/rrac094
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4
Akademický článek
Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors
Autor: Justyna Mika, Sylwia Kabacik, Christophe Badie, Joanna Polanska, Serge M. Candéias
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
The genes coding for the antigenic T cell receptor (TR) subunits are assembled in thymocytes from discrete V, D, and J genes by a site-specific recombination process. A tight control of this activity is required to prevent potentially detrimental rec
Externí odkaz: https://doaj.org/article/1e02b777b1c24c4c81b090db2f85f87d
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6
Low dose ionizing radiation effects on the immune system
Autor: Serge M. Candéias, Olga A. Martin, Alexandros G. Georgakilas, Katalin Lumniczky, Franz Rödel, Gemma Armengol, Sabine Hornhardt, Nathalie Impens, Dörthe Schaue
Publikováno v: Lumniczky, Katalin; Impens, Nathalie; Armengol, Gemma; Candéias, Serge; Georgakilas, Alexandros G.; Hornhardt, Sabine; Martin, Olga A.; Rödel, Franz; Schaue, Dörthe (2021). Low dose ionizing radiation effects on the immune system. Environment International, 149, p. 106212. Elsevier 10.1016/j.envint.2020.106212
Environment international
Environment International, Vol 149, Iss, Pp 106212-(2021)
Environment International
Environment International, Elsevier, 2021, 149, pp.106212. ⟨10.1016/j.envint.2020.106212⟩
Environment International, 2021, 149, pp.106212. ⟨10.1016/j.envint.2020.106212⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International audience; Ionizing radiation interacts with the immune system in many ways with a multiplicity that mirrors thecomplexity of the immune system itself: namely the need to maintain a delicate balance between differentcompartments, cells a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcb9248a4f5141154cb7f132978277c
https://ddd.uab.cat/record/253175
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7
Systemic modulation of stress and immune parameters in patients treated for prostate adenocarcinoma by intensity-modulated radiation therapy or stereotactic ablative body radiotherapy
Autor: Lourdes Cruz-Garcia, A. Napieralska, Katalin Lumniczky, N. Cherradi, Christophe Badie, Isabelle Testard, Joanna Polanska, K. Jelonek, Serge M. Candéias, Benjamin Frey, Justyna Mika, Udo S. Gaipl, Piotr Widlak, Stanislav D. Polozov, C. Roelants
Publikováno v: Strahlentherapie und Onkologie
Strahlentherapie und Onkologie, Springer Verlag (Germany), 2020, 196 (11), pp.‏ 1018-1033. ⟨10.1007/s00066-020-01637-5⟩
Strahlentherapie und Onkologie, 2020, 196 (11), pp.‏ 1018-1033. ⟨10.1007/s00066-020-01637-5⟩
Strahlentherapie Und Onkologie
Background In this exploratory study, the impact of local irradiation on systemic changes in stress and immune parameters was investigated in eight patients treated with intensity-modulated radiation therapy (IMRT) or stereotactic ablative body radio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c025a24c7a8edb69c87408b2112d499
https://hal.archives-ouvertes.fr/hal-02892711
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8
Radiotherapy-Induced Changes in the Systemic Immune and Inflammation Parameters of Head and Neck Cancer Patients
Autor: Udo S. Gaipl, Eric Andreas Rutten, Serge M. Candéias, Géza Sáfrány, Benjamin Frey, Enikő Kis, Katalin Lumniczky, Zsuzsa S Kocsis, Zsolt Jurányi, Enikő Noémi Bogdándi, Katalin Balázs, Christophe Badie, Piotr Widlak, Lourdes Cruz Garcia, Iwona Domińczyk
Publikováno v: Cancers
Cancers, 2019, 11 (9), pp.1324. ⟨10.3390/cancers11091324⟩
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1324 (2019)
Cancers, MDPI, 2019, 11 (9), pp.1324. ⟨10.3390/cancers11091324⟩
International audience; Though radiotherapy is a local therapy, it has systemic effects mainly influencing immune and inflammation processes. This has important consequences in the long-term prognosis and therapy individualization. Our objective was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d7a0261394c3edae1f21d6afaf917a
https://hal.science/hal-02296009
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9
Influence of Confounding Factors on Radiation Dose Estimation Using In Vivo Validated Transcriptional Biomarkers
Autor: Antoine Laval, Grzegorz Woźniak, Navita Somaiah, Piotr Widlak, Lucyna Ponge, Ellen M. Donovan, Grainne O’Brien, Leszek Miszczyk, Lone Gothard, Serge M. Candéias, Isabelle Testard, Elizabeth A. Ainsbury, Christophe Badie, Lourdes Cruz-Garcia, Sue Boyle
Publikováno v: Health Physics
Health Physics, Lippincott, Williams & Wilkins, 2018, 115 (1), pp.90-101. ⟨10.1097/HP.0000000000000844⟩
Health Physics, 2018, 115 (1), pp.90-101. ⟨10.1097/HP.0000000000000844⟩
International audience; For triage purposes following a nuclear accident, blood-based gene expression biomarkers can provide rapid dose estimates for a large number of individuals. Ionizing-radiation-responsive genes are regulated through the DNA dam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0793e82520ec99b89d644afa8411415f
https://pubmed.ncbi.nlm.nih.gov/29787434
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10
Ionizing radiation does not impair the mechanisms controlling genetic stability during T cell receptor gene rearrangement in mice
Autor: Simon Bouffler, Dag M. Eide, Ann-Karin Olsen, Serge M. Candéias, Dag Anders Brede, Sylwia Kabacik, Christophe Badie
Publikováno v: International Journal of Radiation Biology
International Journal of Radiation Biology, Informa Healthcare, 2018, 94 (4), pp.357-365. ⟨10.1080/09553002.2018.1439195⟩
International Journal of Radiation Biology, 2018, 94 (4), pp.357-365. ⟨10.1080/09553002.2018.1439195⟩
International audience; PURPOSE:To determine whether low dose/low dose rate radiation-induced genetic instability may result from radiation-induced inactivation of mechanisms induced by the ATM-dependent DNA damage response checkpoint. To this end, w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29a5b9c329b0a95ec5a2430ce6a3174
https://hal.archives-ouvertes.fr/hal-01726683
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