Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Serge Lebecque"'
Autor:
François Virard, Stéphane Giraud, Mélanie Bonnet, Léa Magadoux, Laetitia Martin, Thuy Ha Pham, Najwa Skafi, Sophie Deneuve, Rita Frem, Bruno O. Villoutreix, Nawal Hajj Sleiman, Jonathan Reboulet, Samir Merabet, Vincent Chaptal, Cédric Chaveroux, Nader Hussein, Nicolas Aznar, Tanguy Fenouil, Isabelle Treilleux, Pierre Saintigny, Stéphane Ansieau, Serge Manié, Serge Lebecque, Toufic Renno, Isabelle Coste
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The quest for targeted therapies is critical in the battle against cancer. The RAS/MAP kinase pathway is frequently implicated in neoplasia, with ERK playing a crucial role as the most distal kinase in the RAS signaling cascade. Our previous
Externí odkaz:
https://doaj.org/article/5f91f695de8442caa6ead3b1243c6294
Autor:
Marie-Anaïs Locquet, Gabriel Ichim, Joseph Bisaccia, Aurelie Dutour, Serge Lebecque, Marie Castets, Kathrin Weber
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract In cancer cells only, TLR3 acquires death receptor properties by efficiently triggering the extrinsic pathway of apoptosis with Caspase-8 as apical protease. Here, we demonstrate that in the absence of Caspase-8, activation of TLR3 can trigg
Externí odkaz:
https://doaj.org/article/02c2b7516d5647c2ac6cdfa292b56d48
Autor:
Alain Calender, Pierre Antoine Rollat Farnier, Adrien Buisson, Stéphane Pinson, Abderrazzaq Bentaher, Serge Lebecque, Harriet Corvol, Rola Abou Taam, Véronique Houdouin, Claire Bardel, Pascal Roy, Gilles Devouassoux, Vincent Cottin, Pascal Seve, Jean-François Bernaudin, Clarice X. Lim, Thomas Weichhart, Dominique Valeyre, Yves Pacheco, Annick Clement, Nadia Nathan, in the frame of GSF (Groupe Sarcoïdose France)
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-19 (2018)
Abstract Background Sarcoidosis (OMIM 181000) is a multi-systemic granulomatous disorder of unknown origin. Despite multiple genome-wide association (GWAS) studies, no major pathogenic pathways have been identified to date. To find out relevant sarco
Externí odkaz:
https://doaj.org/article/4056fb49f80d4471b504aa3aa69fdf58
Autor:
Fabrice Andre, Pedro Romero, Donata Rimoldi, Michel Pierres, Serge Lebecque, Aicha Goubar, Jean-Christophe Sabourin, Marie Pierre Chenard, Rosa Conforti, Catherine Massacrier, Clarisse Dubois, Karine Chemin, Yannis Morel, Carine Asselin-Paturel, Laurence Zitvogel, Bruno Salaun
Supplementary Figure Legends 1-2, Table Legend and Methods from TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a62206b8300b9dbc974769e83602af
https://doi.org/10.1158/0008-5472.22389654
https://doi.org/10.1158/0008-5472.22389654
Autor:
Fabrice Andre, Pedro Romero, Donata Rimoldi, Michel Pierres, Serge Lebecque, Aicha Goubar, Jean-Christophe Sabourin, Marie Pierre Chenard, Rosa Conforti, Catherine Massacrier, Clarisse Dubois, Karine Chemin, Yannis Morel, Carine Asselin-Paturel, Laurence Zitvogel, Bruno Salaun
Supplementary Table 1 from TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54faefa5a5624ecd3d318cf680228b51
https://doi.org/10.1158/0008-5472.22389651
https://doi.org/10.1158/0008-5472.22389651
Autor:
Helena Dragic, Audrey Barthelaix, Cédric Duret, Simon Le Goupil, Hadrien Laprade, Sophie Martin, Sabine Brugière, Yohann Couté, Christelle Machon, Jerome Guitton, Justine Rudewicz, Paul Hofman, Serge Lebecque, Cedric Chaveroux, Carole Ferraro-Peyret, Toufic Renno, Serge N Manié
Publikováno v:
Life Science Alliance
Life Science Alliance, 2022, 5 (7), pp.e202101334. ⟨10.26508/lsa.202101334⟩
Life Science Alliance, 2022, 5 (7), pp.e202101334. ⟨10.26508/lsa.202101334⟩
The glucose-requiring hexosamine biosynthetic pathway (HBP), which produces UDP-N-acetylglucosamine for glycosylation reactions, promotes lung adenocarcinoma (LUAD) progression. However, lung tumor cells often reside in low-nutrient microenvironments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9de2ded202d9df16d9a462ae49b57c
https://hal.science/hal-03660129/document
https://hal.science/hal-03660129/document
Autor:
Serge Lebecque, Sylvie Lantuejoul, Kathrin Weber, Yann Estornes, Marc Grégoire, Toufic Renno, Olivier Micheau, Thomas Daunizeau, Audrey Ziverec, Marion Delphin, Béatrice Vanbervliet-Defrance, Tiphaine Delaunay, Leila Djemal, Christophe Blanquart, Karene Mahtouk, Jean-François Fonteneau, Vahan Kepenekian, Guillaume Passot, Olivier Glehen
Publikováno v:
Cancer Letters
Cancer Letters, Elsevier, 2019, 472, pp.29-39. ⟨10.1016/j.canlet.2019.12.016⟩
Cancer Letters, 2019, 472, pp.29-39. ⟨10.1016/j.canlet.2019.12.016⟩
Cancer Letters, Elsevier, 2019, 472, pp.29-39. ⟨10.1016/j.canlet.2019.12.016⟩
Cancer Letters, 2019, 472, pp.29-39. ⟨10.1016/j.canlet.2019.12.016⟩
International audience; Toll-like receptor 3 (TLR3) is an immune receptor that behaves like a death receptor in tumor cells, thereby providing an original target for cancer therapy. The therapeutic potential of TLR3 targeting in malignant mesotheliom
Autor:
Alain Kfoury, Isabelle Coste, Muriel Le Romancer, Melanie Bonnet, François Virard, Isabelle Treilleux, Kevin Lang, Serge Manié, Toufic Renno, Bassam Badran, Serge Lebecque, Rana El Sabeh, Nader Hussein, Katy Le Corf
Publikováno v:
Journal of Inflammation Research
Journal of Inflammation Research, 2021, 14, pp.2149-2156. ⟨10.2147/JIR.S306805⟩
Journal of Inflammation Research, Dove Medical Press, 2021, Volume 14, pp.2149-2156. ⟨10.2147/JIR.S306805⟩
Journal of Inflammation Research, 2021, 14, pp.2149-2156. ⟨10.2147/JIR.S306805⟩
Journal of Inflammation Research, Dove Medical Press, 2021, Volume 14, pp.2149-2156. ⟨10.2147/JIR.S306805⟩
Rana El Sabeh,1,2 Mélanie Bonnet,1 Katy Le Corf,1 Kevin Lang,1 Alain Kfoury,1 Bassam Badran,2 Nader Hussein,2 Francois Virard,1 Isabelle Treilleux,3 Muriel Le Romancer,1 Serge Lebecque,1 Serge Manie,1 Isabelle Coste,1,* Toufic Renno1,* 1Université
Autor:
François Virard, Toufic Renno, Nolwenn Le Stang, Sylvie Lantuejoul, Yann Estornes, Serge Lebecque, Florent Toscano, Marc Bonnin, Béatrice Vanbervliet, Olivier Micheau, Lugain Alkurdi, Kathrin Weber
Publikováno v:
Cell Death and Disease, Vol 9, Iss 9, Pp 1-14 (2018)
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2018, 9 (9), pp.874. ⟨10.1038/s41419-018-0850-0⟩
Cell Death and Disease, 2018, 9 (9), pp.874. ⟨10.1038/s41419-018-0850-0⟩
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2018, 9 (9), pp.874. ⟨10.1038/s41419-018-0850-0⟩
Cell Death and Disease, 2018, 9 (9), pp.874. ⟨10.1038/s41419-018-0850-0⟩
Cell Death & Disease
Toll-like receptor 3 (TLR3) mediates innate immune responses by sensing viral dsRNA, but also induces apoptosis selectively in cancer cells. Our analysis by immunohistochemistry revealed that TLR3 is frequently overexpressed in 130 non-small cell lun
Autor:
Annick Clement, Yves Pacheco, Jean-François Bernaudin, Gilles Devouassoux, Adrien Buisson, Clarice X. Lim, Dominique Valeyre, Vincent Cottin, Claire Bardel, Alain Calender, Serge Lebecque, Pascal Sève, Pierre Antoine Rollat Farnier, Stéphane Pinson, Harriet Corvol, Abderrazzaq Bentaher, Pascal Roy, Rola Abou Taam, Thomas Weichhart, Nadia Nathan, Véronique Houdouin
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-19 (2018)
BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2018, 11 (1), pp.23. ⟨10.1186/s12920-018-0338-x⟩
BMC Medical Genomics, 2018, 11 (1), pp.23. ⟨10.1186/s12920-018-0338-x⟩
BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2018, 11 (1), pp.23. ⟨10.1186/s12920-018-0338-x⟩
BMC Medical Genomics, 2018, 11 (1), pp.23. ⟨10.1186/s12920-018-0338-x⟩
Background Sarcoidosis (OMIM 181000) is a multi-systemic granulomatous disorder of unknown origin. Despite multiple genome-wide association (GWAS) studies, no major pathogenic pathways have been identified to date. To find out relevant sarcoidosis pr