Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Serge L, Boulet"'
Autor:
Junliang, Hao, James P, Beck, John M, Schaus, Joseph H, Krushinski, Qi, Chen, Christopher D, Beadle, Paloma, Vidal, Matthew R, Reinhard, Bruce A, Dressman, Steven M, Massey, Serge L, Boulet, Michael P, Cohen, Brian M, Watson, David, Tupper, Kevin M, Gardinier, Jason, Myers, Anette M, Johansson, Jeffery, Richardson, Daniel S, Richards, Erik J, Hembre, David M, Remick, David A, Coates, Rajni M, Bhardwaj, Benjamin A, Diseroad, David, Bender, Greg, Stephenson, Craig D, Wolfangel, Nuria, Diaz, Brian G, Getman, Xu-Shan, Wang, Beverly A, Heinz, Jeff W, Cramer, Xin, Zhou, Deanna L, Maren, Julie F, Falcone, Rebecca A, Wright, Stephen N, Mitchell, Guy, Carter, Charles R, Yang, Robert F, Bruns, Kjell A, Svensson
Publikováno v:
Journal of medicinal chemistry. 62(19)
Clinical development of catechol-based orthosteric agonists of the dopamine D1 receptor has thus far been unsuccessful due to multiple challenges. To address these issues, we identified LY3154207 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38771cd6f379be26a1a0dc76826df19b
https://pubmed.ncbi.nlm.nih.gov/31532644
https://pubmed.ncbi.nlm.nih.gov/31532644
Autor:
Leo A. Paquette, Serge L. Boulet
Publikováno v:
Synthesis. 2002:895-900
An attempt to access in an enantioselective fashion, a highly substituted cyclohexane as required for the northeastern sector of okilactomycin is described. The application of Oppolzer's sultam chemistry, involving in particular an optically and chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d85b5712bdba5dba74459a06cc1b2e
https://doi.org/10.1055/s-2002-28511
https://doi.org/10.1055/s-2002-28511
Autor:
Serge L. Boulet, Leo A. Paquette
Publikováno v:
Synthesis. 2002:888-894
A synthesis of the western half of the macrocyclic ring framework of the antitumor antibiotic okilactomycin is described. The strategy employed rests on an efficient synthesis of meso-2,4-dimethylglutaric anhydride and ensuing resolution via reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2517399b4bde4ba75f7334781e6c1d18
https://doi.org/10.1055/s-2002-28510
https://doi.org/10.1055/s-2002-28510
Autor:
Serge L. Boulet, Edward Piers
Publikováno v:
Tetrahedron Letters. 38:8815-8818
Efficient total syntheses of the racemic versions of the diterpenoids verrucosan-2β-ol ( 5 ), neoverrucosan-5β-ol ( 6 ), and homoverrucosan-5β-ol ( 7 ) are described. The production of the key intermediate 15 suggests a possible synthetic approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db53bb2732e0a342a9aa7240f603c73b
https://doi.org/10.1016/s0040-4039(97)10507-x
https://doi.org/10.1016/s0040-4039(97)10507-x
Autor:
Edward Piers, Serge L. Boulet
Publikováno v:
ChemInform. 29
Efficient total syntheses of the racemic versions of the diterpenoids verrucosan-2β-ol ( 5 ), neoverrucosan-5β-ol ( 6 ), and homoverrucosan-5β-ol ( 7 ) are described. The production of the key intermediate 15 suggests a possible synthetic approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80e78c61703d8c3fc4aaece83b125fae
https://doi.org/10.1002/chin.199812160
https://doi.org/10.1002/chin.199812160
Autor:
Serge L. Boulet, Edward Piers
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bffa8554443911f0d3fd6e94e4e5c7
https://doi.org/10.1002/chin.199833078
https://doi.org/10.1002/chin.199833078
Autor:
Leo A. Paquette, Serge L. Boulet
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2973d30906aaef793912466e77065d
https://doi.org/10.1002/chin.200239219
https://doi.org/10.1002/chin.200239219
Autor:
Leo A. Paquette, Serge L. Boulet
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7e303a84e860c033ed9a8e8da4bb445
https://doi.org/10.1002/chin.200242238
https://doi.org/10.1002/chin.200242238
Autor:
Edward Piers, Serge L. Boulet
Publikováno v:
Synlett. 1998:516-518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e98d668ef236642cc20ba5ba7cd3252
https://doi.org/10.1055/s-1998-1707
https://doi.org/10.1055/s-1998-1707
Autor:
Akio Murai, Kenshu Fujiwara, Leo A. Paquette, Serge L. Boulet, Louis Barriault, Mari Yotsu-Yamashita
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(14)
Second generation analogs of polycavernoside A (2) possessing a side chain at C-15 different from that of the natural toxin have been synthesized. The in vivo toxicities of these new compounds (expressed as the minimal lethal dose) have been evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c78bf3a21fab0915fead946bc04a49
https://pubmed.ncbi.nlm.nih.gov/10450983
https://pubmed.ncbi.nlm.nih.gov/10450983