Phase 1 study of intraventricular 131I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies

Autor: Kim Kramer, Neeta Pandit-Taskar, Brian H. Kushner, Pat Zanzonico, John L. Humm, Ursula Tomlinson, Maria Donzelli, Suzanne L. Wolden, Sophia Haque, Ira Dunkel, Mark M. Souweidane, Jeffrey P. Greenfield, Satish Tickoo, Jason S. Lewis, Serge K. Lyashchenko, Jorge A. Carrasquillo, Bae Chu, Christopher Horan, Steven M. Larson, Nai-Kong V. Cheung, Shakeel Modak

Publikováno v: Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-12 (2022)

Abstract Background The prognosis for metastatic and recurrent tumors of the central nervous system (CNS) remains dismal, and the need for newer therapeutic targets and modalities is critical. The cell surface glycoprotein B7H3 is expressed on a rang

Externí odkaz: https://doaj.org/article/efc8fef816994f42bd7ff478e4d20251

I-124 codrituzumab imaging and biodistribution in patients with hepatocellular carcinoma

Autor: Jorge A. Carrasquillo, Joseph A. O’Donoghue, Volkan Beylergil, Shutian Ruan, Neeta Pandit-Taskar, Steven M. Larson, Peter M. Smith-Jones, Serge K. Lyashchenko, Norihisa Ohishi, Toshihiko Ohtomo, Ghassan K. Abou-Alfa

Publikováno v: EJNMMI Research, Vol 8, Iss 1, Pp 1-11 (2018)

Abstract Background I-124 codrituzumab (aka GC33), an antibody directed at Glypican 3, was evaluated in patients with hepatocellular carcinoma (HCC). Fourteen patients with HCC underwent baseline imaging with I-124 codrituzumab (~ 185 MBq, 10 mg). Se

Externí odkaz: https://doaj.org/article/58e51e59a3e54e3985147d1bf44c110e

Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial

Autor: Anani Badje, MPH, Raoul Moh, PhD, Delphine Gabillard, MSc, Calixte Guéhi, PhD, Mathieu Kabran, PharmD, Jean-Baptiste Ntakpé, MPH, Jérôme Le Carrou, PhD, Gérard M Kouame, MPH, Eric Ouattara, PhD, Eugène Messou, PhD, Amani Anzian, MD, Albert Minga, PhD, Joachim Gnokoro, MD, Patrice Gouesse, MD, Arlette Emieme, PharmD, Thomas-d'Aquin Toni, PhD, Cyprien Rabe, MD, Baba Sidibé, MD, Gustave Nzunetu, MD, Lambert Dohoun, MD, Abo Yao, MPH, Synali Kamagate, MD, Solange Amon, MD, Amadou-Barenson Kouame, MD, Aboli Koua, MD, Emmanuel Kouamé, MD, Marcelle Daligou, MD, Denise Hawerlander, MD, Simplice Ackoundzé, MD, Serge Koule, MD, Jonas Séri, MD, Alex Ani, MD, Fassery Dembélé, MD, Fatoumata Koné, MD, Mykayila Oyebi, MD, Nathalie Mbakop, MD, Oyewole Makaila, MD, Carolle Babatunde, MD, Nathaniel Babatunde, MD, Gisèle Bleoué, MD, Mireille Tchoutedjem, MD, Alain-Claude Kouadio, MD, Ghislaine Sena, MD, Sahinou-Yediga Yededji, MD, Sophie Karcher, MSc, Prof Christine Rouzioux, PhD, Abo Kouame, MD, Rodrigue Assi, MD, Alima Bakayoko, MD, Prof Serge K Domoua, PhD, Nina Deschamps, MPH, Prof Kakou Aka, MD, Prof Thérèse N'Dri-Yoman, MD, Prof Roger Salamon, PhD, Valérie Journot, PhD, Prof Hughes Ahibo, PhD, Prof Timothée Ouassa, PhD, Prof Hervé Menan, PhD, Prof André Inwoley, PhD, Christine Danel, PhD, Prof Serge P Eholié, PhD, Dr Xavier Anglaret, PhD, Anani Badje, Raoul Moh, Delphine Gabillard, Calixte Guéhi, Mathieu Kabran, Jean-Baptiste Ntakpé, Jérôme Le Carrou, Gérard-Menan Kouame, Eric Ouattara, Eugène Messou, Amani Anzian, Albert Minga, Joachim Gnokoro, Patrice Gouesse, Arlette Emieme, Thomas-d'Aquin Toni, Cyprien Rabe, Baba Sidibé, Gustave Nzunetu, Lambert Dohoun, Yao Abo, Synali Kamagate, Solange Amon, Amadou-Barenson Kouame, Aboli Koua, Emmanuel Kouamé, Marcelle Daligou, Denise Hawerlander, Simplice Ackoundzé, Serge Koule, Jonas Séri, Alex Ani, Fassery Dembélé, Fatoumata Koné, Mykayila Oyebi, Nathalie Mbakop, Oyewole Makaila, Carolle Babatunde, Nathaniel Babatunde, Gisèle Bleoué, Mireille Tchoutedjem, Alain-Claude Kouadio, Ghislaine Sena, Sahinou-Yediga Yededji, Sophie Karcher, Christine Rouzioux, Abo Kouame, Rodrigue Assi, Alima Bakayoko, Serge-K. Domoua, Nina Deschamps, Kakou Aka, Thérèse N'Dri-Yoman, Roger Salamon, Valérie Journot, Hughes Ahibo, Timothée Ouassa, Hervé Ménan, André Inwoley, Ben-Ahoussi Ndja, Blandine Adou, Constance Kanga, Eba Aoussi, Emmanuel Bissagnene, Olivier Ba-Gomis, Yves-Alain Zike, Claude Akakpo, Madeleine Sassan-Morokro, Max Mobio, Bamba Doféré, Koman Mesmin, Alain Attia, Alassane Mahassadi, Apollinaire Horo, Armel Oussou, Marie-Laure Chaix, Gilles Peytavin, Mariatou Koné, Kouamé N'Guessan, Raïmi Fassassi, Serge Niangoran, Annabel Desgrées-du-Loû, France Lert, Rosemary Dray Spira, Kevin Jean, Romuald Konan, Franck Bohoussou, Cyril Yao-Yapi, Larissa N'guessan-Koffi, Bertine Siloué, Adoulaye Cissé, Adrienne Aboua, Sylvie Konan, Antoine Kouamé, Celestin N'Chot, Elvis Amani, Gwenaëlle Clouet, Bruno Debono, Geneviève Chêne, Mireille Dosso, Pierre-Marie Girard, Vincent Jarlier, Jean-Marie Masumbuko, Christian Perronne, Papa-Salif Sow, Christine Danel, Serge-Paul Eholié, Xavier Anglaret

Publikováno v: The Lancet Global Health, Vol 5, Iss 11, Pp e1080-e1089 (2017)

Background: Temprano ANRS 12136 was a factorial 2 × 2 trial that assessed the benefits of early antiretroviral therapy (ART; ie, in patients who had not reached the CD4 cell count threshold used to recommend starting ART, as per the WHO guidelines t

Externí odkaz: https://doaj.org/article/c5d7eb49263d4e08a3d2d62ed936400d

Mixed-forest species establishment in a monodominant forest in central Africa: implications for tropical forest invasibility.

Autor: Kelvin S-H Peh, Bonaventure Sonké, Olivier Séné, Marie-Noël K Djuikouo, Charlemagne K Nguembou, Hermann Taedoumg, Serge K Begne, Simon L Lewis

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e97585 (2014)

BACKGROUND: Traits of non-dominant mixed-forest tree species and their synergies for successful co-occurrence in monodominant Gilbertiodendron dewevrei forest have not yet been investigated. Here we compared the tree species diversity of the monodomi

Externí odkaz: https://doaj.org/article/1050ec0545414490b154d52c31dceb81

Prozessfaktoren im Therapieverlauf: Der Verlauf der therapeutischen Beziehung, Änderungs- und Zielorientierung und Zufriedenheit von Patienten und Therapeuten in den ersten 20 Sitzungen und dessen Bedeutung für den Therapieerfolg.

Autor: Sulz, Serge K. D. Prof.Sulz@eupehs.org, Oswald, Jana, Sichort-Hebing, Miriam

Publikováno v: Psychotherapie (2364-1517). 2024, Vol. 29 Issue 2, p85-95. 11p.