Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Serge Bouaziz"'
Autor:
Elodie Bosc, Julie Anastasie, Feryel Soualmia, Pascale Coric, Ju Youn Kim, Lily Q. Wang, Gullen Lacin, Kaitao Zhao, Ronak Patel, Eric Duplus, Philippe Tixador, Andrew A. Sproul, Bernard Brugg, Michelle Reboud-Ravaux, Carol M. Troy, Michael L. Shelanski, Serge Bouaziz, Michael Karin, Chahrazade El Amri, Etienne D. Jacotot
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-14 (2022)
Abstract Caspase-2 (Casp2) is a promising therapeutic target in several human diseases, including nonalcoholic steatohepatitis (NASH) and Alzheimer’s disease (AD). However, the design of an active-site-directed inhibitor selective to individual cas
Externí odkaz:
https://doaj.org/article/e2ca2ef1c4d34003bb95c448c8eb4433
Autor:
Nathalie Chazal, Hugues de Rocquigny, Philippe Roussel, Serge Bouaziz, Françoise Barré-Sinoussi, Jean-François Delfraissy, Jean-Luc Darlix
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://doaj.org/article/aede8158463e4ddc9d784104c0a34f9a
Autor:
Rafael Gomes Von Borowski, Sophie Chat, Rafael Schneider, Sylvie Nonin-Lecomte, Serge Bouaziz, Emmanuel Giudice, Aline Rigon Zimmer, Simone Cristina Baggio Gnoatto, Alexandre José Macedo, Reynald Gillet
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Staphylococci are pathogenic biofilm-forming bacteria and a source of multidrug resistance and/or tolerance causing a broad spectrum of infections. These bacteria are enclosed in a matrix that allows them to colonize medical devices, such as
Externí odkaz:
https://doaj.org/article/465974453a2e458c9a809ec7acc91333
Autor:
Guillaume Le Guyader, Bernard Do, Ivo B. Rietveld, Pascale Coric, Serge Bouaziz, Jean-Michel Guigner, Philippe-Henri Secretan, Karine Andrieux, Muriel Paul
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 569 (2022)
Facial angiofibromas (FA) are one of the most obvious cutaneous manifestations of tuberous sclerosis complex. Topical rapamycin for angiofibromas has been reported as a promising treatment. Several types of vehicles have been used hitherto, but polym
Externí odkaz:
https://doaj.org/article/51227dd701c843f8b047dc46ce9e5319
Autor:
Jean-François Gaucher, Marie Reille-Seroussi, Nathalie Gagey-Eilstein, Sylvain Broussy, Pascale Coric, Bili Seijo, Marie-Bernard Lascombe, Benoit Gautier, Wang-Quing Liu, Florent Huguenot, Nicolas Inguimbert, Serge Bouaziz, Michel Vidal, Isabelle Broutin
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167755 (2016)
Angiogenesis is tightly regulated through the binding of vascular endothelial growth factors (VEGFs) to their receptors (VEGFRs). In this context, we showed that human VEGFR1 domain 2 crystallizes in the presence of Zn2+, Co2+ or Cu2+ as a dimer that
Externí odkaz:
https://doaj.org/article/945d9e856baa4145be209985052c44c6
Autor:
Nassima Oumata, Phu Hai Nguyen, Vincent Beringue, Flavie Soubigou, Yanhong Pang, Nathalie Desban, Catherine Massacrier, Yannis Morel, Carine Paturel, Marie-Astrid Contesse, Serge Bouaziz, Suparna Sanyal, Hervé Galons, Marc Blondel, Cécile Voisset
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72112 (2013)
Using a yeast-based assay, a previously unsuspected antiprion activity was found for imiquimod (IQ), a potent Toll-like receptor 7 (TLR7) agonist already used for clinical applications. The antiprion activity of IQ was first detected against yeast pr
Externí odkaz:
https://doaj.org/article/a4b784225de84e31be0ddc49b96770c7
Autor:
Claire Maudet, Adèle Sourisce, Loïc Dragin, Hichem Lahouassa, Jean-Christophe Rain, Serge Bouaziz, Bertha Cécilia Ramirez, Florence Margottin-Goguet
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77320 (2013)
The Vpr protein from type 1 and type 2 Human Immunodeficiency Viruses (HIV-1 and HIV-2) is thought to inactivate several host proteins through the hijacking of the DCAF1 adaptor of the Cul4A ubiquitin ligase. Here, we identified two transcriptional r
Externí odkaz:
https://doaj.org/article/a1bf6b764bdc48eaaa80f76809438c1e
Autor:
Gregory Berger, Stéphanie Durand, Guillaume Fargier, Xuan-Nhi Nguyen, Stéphanie Cordeil, Serge Bouaziz, Delphine Muriaux, Jean-Luc Darlix, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002221 (2011)
Myeloid cells play numerous roles in HIV-1 pathogenesis serving as a vehicle for viral spread and as a viral reservoir. Yet, cells of this lineage generally resist HIV-1 infection when compared to cells of other lineages, a phenomenon particularly ac
Externí odkaz:
https://doaj.org/article/d3f0ac5822da41aa8b696e73fc9f052a
Autor:
Gaëlle Gonzalez, Sandrina DaFonseca, Elisabeth Errazuriz, Pascale Coric, Florence Souquet, Serge Turcaud, Pierre Boulanger, Serge Bouaziz, Saw See Hong
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27234 (2011)
The HIV-1 auxiliary protein Vpr and Vpr-fusion proteins can be copackaged with Gag precursor (Pr55Gag) into virions or membrane-enveloped virus-like particles (VLP). Taking advantage of this property, we developed a simple and sensitive method to eva
Externí odkaz:
https://doaj.org/article/3cd2480a46d64552b560e821c1be7403
Publikováno v:
Biomolecular NMR Assignments
Biomolecular NMR Assignments, Springer, 2021, 15 (2), pp.267-271. ⟨10.1007/s12104-021-10016-9⟩
Biomolecular NMR Assignments, Springer, 2021, 15 (2), pp.267-271. ⟨10.1007/s12104-021-10016-9⟩
During the maturation of the HIV-1 particle, the Gag polyprotein is cleaved by the viral protease into several proteins: matrix (MA), capsid (CA), spacer peptide 1 (SP1), nucleocapsid (NC), spacer peptide 2 (SP2) and p6. After cleavage, these protein