Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Serene Alexander"'
Autor:
Shendong Yuan, Mark E. Sullivan, Judi Bryant, Serene Alexander, Brad O. Buckman, Mike Snider, Babu Subramanyam, Yi-Xin Wang, Joseph Post, Imadul Islam, Lorraine Kent, Jih-Lie Tseng, John Morser, Sabine Schirm
Publikováno v:
Thrombosis Research. 122:523-532
ADP plays a key role in platelet aggregation which has led to the development of antiplatelet drugs that target the P2Y12 receptor. The aim of this study was to characterize the effects of two novel P2Y12 receptor antagonists, BX 667 and its active m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06449e5dacf1d2aa304fd696e5b41090
https://doi.org/10.1016/j.thromres.2008.03.026
https://doi.org/10.1016/j.thromres.2008.03.026
Autor:
Yi-Xin Wang, Baby Martin-McNulty, Brent Larsen, Serene Alexander, Kirk Mclean, Jon Vincelette, David R. Light, Chenliang Wu
Publikováno v:
Thrombosis and Haemostasis. 96:317-324
SummaryTissue factor (TF) exposure isa potent pro-thrombotic trigger that initiates activation of the coagulation cascade, while thrombomodulin (TM) is a potent anticoagulant protein that limits the extent of activation. Both TF neutralizing antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaf3f1263233abd7b330beb5cbbfdb1
https://doi.org/10.1160/th06-04-0219
https://doi.org/10.1160/th06-04-0219
Autor:
Mark E. Sullivan, Judi Bryant, Yi-Xin Wang, Serene Alexander, Valdeci da Cunha, William P. Dole, Baby Martin-McNulty, Jon Vincelette, Richard M. Fitch, Babu Subramanyam, Brad O. Buckman, Joseph Post, Imadul Islam, Cornell Mallari, John Morser, Shendong Yuan, Ronald Vergona
Publikováno v:
Thrombosis and haemostasis. 97(5)
SummaryIrreversible platelet inhibitors, such as aspirin and clopidogrel, have limited anti-thrombotic efficacy in the clinic due to their bleeding risk. We have developed an orally active reversible P2Y12 receptor antagonist, BX 667.The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89ca4e93cf8b7eb8cb9abe96e885747
https://pubmed.ncbi.nlm.nih.gov/17479197
https://pubmed.ncbi.nlm.nih.gov/17479197