The Pathologic Diagnosis of Pediatric Soft Tissue Tumors in the Era of Molecular Medicine: The Sarcoma Pediatric Pathology Research Interest Group Perspective

Autor: Jennifer O. Black, Alyaa Al-Ibraheemi, Michael A. Arnold, Cheryl M. Coffin, Jessica L. Davis, David M. Parham, Erin R. Rudzinski, Archana Shenoy, Lea F. Surrey, Serena Y. Tan, Sheri L. Spunt

Publikováno v: Archives of Pathology & Laboratory Medicine.

Context.— Pediatric soft tissue tumors are one of the areas of pediatric pathology that frequently generate consult requests. Evolving classification systems, ancillary testing methods, new treatment options, research enrollment opportunities, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f4eb09f1d3ad34a5a9cb1ec3a6c577b
https://doi.org/10.5858/arpa.2022-0364-ra

ALK rearrangements in infantile fibrosarcoma‐like spindle cell tumours of soft tissue and kidney

Autor: Alyaa Al-Ibraheemi, Serena Y. Tan, Yajuan J. Liu, Erin R. Rudzinski, William A Arhens, Cheryl M. Coffin, Sheri L. Spunt, Julie C. Fanburg-Smith, Jessica L. Davis, Javier Oesterheld

Publikováno v: Histopathology. 80:698-707

Recurrent alterations in receptor tyrosine kinase (RTK) and downstream effectors are described in infantile fibrosarcoma (IFS)/cellular congenital mesoblastic nephroma (cCMN) and a subset of spindle cell sarcomas, provisionally designated 'NTRK-rearr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bbcabd054308338bdd310b8455d60b
https://doi.org/10.1111/his.14603

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

Autor: Robert C, Jones, Jim, Karkanias, Mark A, Krasnow, Angela Oliveira, Pisco, Stephen R, Quake, Julia, Salzman, Nir, Yosef, Bryan, Bulthaup, Phillip, Brown, William, Harper, Marisa, Hemenez, Ravikumar, Ponnusamy, Ahmad, Salehi, Bhavani A, Sanagavarapu, Eileen, Spallino, Ksenia A, Aaron, Waldo, Concepcion, James M, Gardner, Burnett, Kelly, Nikole, Neidlinger, Zifa, Wang, Sheela, Crasta, Saroja, Kolluru, Maurizio, Morri, Serena Y, Tan, Kyle J, Travaglini, Chenling, Xu, Marcela, Alcántara-Hernández, Nicole, Almanzar, Jane, Antony, Benjamin, Beyersdorf, Deviana, Burhan, Kruti, Calcuttawala, Matthew M, Carter, Charles K F, Chan, Charles A, Chang, Stephen, Chang, Alex, Colville, Rebecca N, Culver, Ivana, Cvijović, Gaetano, D'Amato, Camille, Ezran, Francisco X, Galdos, Astrid, Gillich, William R, Goodyer, Yan, Hang, Alyssa, Hayashi, Sahar, Houshdaran, Xianxi, Huang, Juan C, Irwin, SoRi, Jang, Julia Vallve, Juanico, Aaron M, Kershner, Soochi, Kim, Bernhard, Kiss, William, Kong, Maya E, Kumar, Angera H, Kuo, Rebecca, Leylek, Baoxiang, Li, Gabriel B, Loeb, Wan-Jin, Lu, Sruthi, Mantri, Maxim, Markovic, Patrick L, McAlpine, Antoine, de Morree, Karim, Mrouj, Shravani, Mukherjee, Tyler, Muser, Patrick, Neuhöfer, Thi D, Nguyen, Kimberly, Perez, Ragini, Phansalkar, Nazan, Puluca, Zhen, Qi, Poorvi, Rao, Hayley, Raquer-McKay, Nicholas, Schaum, Bronwyn, Scott, Bobak, Seddighzadeh, Joe, Segal, Sushmita, Sen, Shaheen, Sikandar, Sean P, Spencer, Lea C, Steffes, Varun R, Subramaniam, Aditi, Swarup, Michael, Swift, Will, Van Treuren, Emily, Trimm, Stefan, Veizades, Sivakamasundari, Vijayakumar, Kim Chi, Vo, Sevahn K, Vorperian, Wanxin, Wang, Hannah N W, Weinstein, Juliane, Winkler, Timothy T H, Wu, Jamie, Xie, Andrea R, Yung, Yue, Zhang, Angela M, Detweiler, Honey, Mekonen, Norma F, Neff, Rene V, Sit, Michelle, Tan, Jia, Yan, Gregory R, Bean, Vivek, Charu, Erna, Forgó, Brock A, Martin, Michael G, Ozawa, Oscar, Silva, Angus, Toland, Venkata N P, Vemuri, Shaked, Afik, Kyle, Awayan, Olga Borisovna, Botvinnik, Ashley, Byrne, Michelle, Chen, Roozbeh, Dehghannasiri, Adam, Gayoso, Alejandro A, Granados, Qiqing, Li, Gita, Mahmoudabadi, Aaron, McGeever, Julia Eve, Olivieri, Madeline, Park, Neha, Ravikumar, Geoff, Stanley, Weilun, Tan, Alexander J, Tarashansky, Rohan, Vanheusden, Peter, Wang, Sheng, Wang, Galen, Xing, Rebecca, Culver, Les, Dethlefsen, Po-Yi, Ho, Shixuan, Liu, Jonathan S, Maltzman, Ross J, Metzger, Koki, Sasagawa, Rahul, Sinha, Hanbing, Song, Bruce, Wang, Steven E, Artandi, Philip A, Beachy, Michael F, Clarke, Linda C, Giudice, Franklin W, Huang, Kerwyn Casey, Huang, Juliana, Idoyaga, Seung K, Kim, Mark, Krasnow, Christin S, Kuo, Patricia, Nguyen, Thomas A, Rando, Kristy, Red-Horse, Jeremy, Reiter, David A, Relman, Justin L, Sonnenburg, Albert, Wu, Sean M, Wu, Tony, Wyss-Coray

Publikováno v: Science
Tabula Sapiens Consortium* 2022, ' The Tabula Sapiens : A multiple-organ, single-cell transcriptomic atlas of humans ', Science (New York, N.Y.), vol. 376, no. 6594, pp. eabl4896 . https://doi.org/10.1126/science.abl4896

INTRODUCTION: Although the genome is often called the blueprint of an organism, it is perhaps more accurate to describe it as a parts list composed of the various genes that may or may not be used in the different cell types of a multicellular organi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f726fc016f86cd4ce8c15a69dce9f6be
https://pubmed.ncbi.nlm.nih.gov/36198687

Dissecting the Cardiac Conduction System: Is It Worthwhile?

Autor: Steven White, Nicoleta C. Arva, Serena Y. Tan, Michael K. Fritsch

Publikováno v: Pediatric and Developmental Pathology. 23:413-423

Background Pathologic examination of conduction system (CS) is not routinely performed, and histologic changes are mostly reported in forensic practice. Methods We studied the value of dissecting the CS in a cohort of pediatric patients with unexplai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7487cc113d32d9a8e8e6f94c51da0143
https://doi.org/10.1177/1093526620944756

Leiomyomatosis in an Infant With a SUFU Splice Site Variant: Case Report

Autor: Rameshwar R. Rao, Ben W. Dulken, Dena R. Matalon, Maia Borensztein, Molly McGuinness, Stephanie M. Cizek, Matias Bruzoni, Serena Y. Tan, Sara Kreimer

Publikováno v: Journal of pediatric hematology/oncology. 44(5)

Heterozygous loss-of-function variants in the suppressor of fused protein gene (SUFU) can result in Gorlin syndrome, which is characterized by an increased frequency of basal cell carcinoma, medulloblastoma, odontogenic keratocysts, as well as other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebbf6bcfbfc3c2b103242cdffa6a92c
https://pubmed.ncbi.nlm.nih.gov/35398865