Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Serena Viappiani"'
Autor:
Ilenia Gatto, Emanuela Biagioni, Irene Coloretti, Serena Viappiani, Stefano Busani, Massimo Girardis
Publikováno v:
Journal of Anesthesia, Analgesia and Critical Care, Vol 2, Iss 1, Pp 1-3 (2022)
Abstract The ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO2/FiO2) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. In these patients, the assessm
Externí odkaz:
https://doaj.org/article/d4f3f5f6c9f247aa9afcf072daa7477e
Autor:
Serena Viappiani, Yu Zhu, Christopher Power, Kristofor K. Ellestad, Janet Holden, Ferdinand Maingat, Pornpun Vivithanaporn, Claudia Silva
Publikováno v:
The Journal of Immunology. 184:1566-1574
Lentivirus infections including HIV and feline immunodeficiency virus (FIV) cause neurovirulence, which is largely mediated by innate immunity. To investigate the interactions between neurovirulence and repeated conditioning by innate immune activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856b2eba26b1e1b3a1bb424be91157bc
https://doi.org/10.4049/jimmunol.0902575
https://doi.org/10.4049/jimmunol.0902575
Autor:
Hernando Leon, Grzegorz Sawicki, Tyler van Mulligen, Adrian C. Nicolescu, Andrew Holt, Bryan D. Crawford, Serena Viappiani, Richard Schulz
Publikováno v:
Biochemical Pharmacology. 77:826-834
Matrix metalloproteinase-2 (MMP-2) has emerged as a key protease in various pathologies associated with oxidative stress, including myocardial ischemia-reperfusion, heart failure or inflammation. Peroxynitrite (ONOO(-)), an important effector of oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92c115057f733e60d8fabbb5720ea31
https://doi.org/10.1016/j.bcp.2008.11.004
https://doi.org/10.1016/j.bcp.2008.11.004
Autor:
Bo Carlsson, Vida Gendviliene, Kanigula Mubagwa, Regina Macianskiene, Serena Viappiani, Bodo Brandts
Publikováno v:
Cardiovascular Drug Reviews. 21:216-235
KB130015 (KB015), a new drug structurally related to amiodarone, has been proposed to have antiarrhythmic properties. In contrast to amiodarone, KB015 markedly slows the kinetics of inactivation of Na(+) channels by enhancing concentration-dependentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bb7cf3bc33620c0066b92d209ec764
https://doi.org/10.1111/j.1527-3466.2003.tb00117.x
https://doi.org/10.1111/j.1527-3466.2003.tb00117.x
Publikováno v:
British Journal of Pharmacology. 145:43-49
Matrix metalloproteinase (MMP) activity is upregulated in pathologies such as atherosclerosis during which endogenous nitric oxide (NO) biosynthesis is reduced. Diminished levels of NO, an antioxidant species, may result in higher oxidative stress. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf64b00b66902dc5070f118a869463ea
https://doi.org/10.1038/sj.bjp.0706144
https://doi.org/10.1038/sj.bjp.0706144
Autor:
Carola Buccellati, Giancarlo Folco, A. Hernandez, Francesca Fumagalli, Saula Ravasi, Serena Viappiani, Angelo Sala, Albino Bonazzi, Simona Zarini, G Chiesa, Manlio Bolla, Piero Zannini, T. Viganò
Publikováno v:
Scopus-Elsevier
We studied the effect of endogenous and exogenous prostaglandin E(2) (PGE(2)), a metabolite of arachidonic acid through the cyclooxygenase (COX) pathway, on interleukin (IL)-1 beta-induced COX-2 expression, using primary cultures of human bronchial s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d1425f4f4a457c1dd57281e2f82de7
https://doi.org/10.1164/ajrccm.162.6.2003127
https://doi.org/10.1164/ajrccm.162.6.2003127
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 341(2)
Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donors (CINODs) are designed to inhibit COX-1 and COX-2 while releasing NO. COX inhibition is responsible for anti-inflammatory and pain-relieving effects, whereas NO donation can improve microcircula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242084f192279cb6c3dd752a283a670e
https://pubmed.ncbi.nlm.nih.gov/22344408
https://pubmed.ncbi.nlm.nih.gov/22344408
Publikováno v:
ChemInform. 33
Cysteinyl leukotrienes (Cys-LT) are powerful proinflammatory autacoids that cause long-lasting bronchoconstriction, plasma leakage, increased mucus production; their biological activity suggests a prominent role in the etiopathology of asthma and sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98f406714c37a046d39799b25adae291
https://doi.org/10.1002/chin.200247243
https://doi.org/10.1002/chin.200247243
Publikováno v:
Trends in pharmacological sciences. 30(3)
Nonsteroidal anti-inflammatory drugs (NSAIDs) remain the most commonly used medications for the treatment of the symptoms of many chronic inflammatory diseases, including osteoarthritis. Unfortunately, the toxicity of NSAIDs substantially limits thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5525be966ada0d0dc0ad8e726d2d66a0
https://pubmed.ncbi.nlm.nih.gov/19230986
https://pubmed.ncbi.nlm.nih.gov/19230986
Publikováno v:
Current pharmaceutical design. 12(23)
Liver ischemia-reperfusion injury is characterized by cell necrosis and apoptosis and by profound modifications in the extracellular matrix (ECM). During the complex series of events that take place both during ischemia and when normal blood flow is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c299d1821b04e843d3d906e1d17e8942
https://pubmed.ncbi.nlm.nih.gov/16918422
https://pubmed.ncbi.nlm.nih.gov/16918422