Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Serena T Bruens"'
Autor:
Kishan A T Naipal, Anja Raams, Serena T Bruens, Inger Brandsma, Nicole S Verkaik, Nicolaas G J Jaspers, Jan H J Hoeijmakers, Geert J L H van Leenders, Joris Pothof, Roland Kanaar, Joost Boormans, Dik C van Gent
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0126029 (2015)
Bladder cancer has a high incidence with significant morbidity and mortality. Attenuated expression of the DNA damage response protein Xeroderma Pigmentosum complementation group C (XPC) has been described in bladder cancer. XPC plays an essential ro
Externí odkaz:
https://doaj.org/article/ea3f2b994d0f42af98b9ca103f83e8f6
Autor:
Akos Gyenis, Jiang Chang, Joris J. P. G. Demmers, Serena T. Bruens, Sander Barnhoorn, Renata M. C. Brandt, Marjolein P. Baar, Marko Raseta, Kasper W. J. Derks, Jan H. J. Hoeijmakers, Joris Pothof
Publikováno v:
Nature Genetics, 55(2), 268-279. Nature Publishing Group
Gene expression profiling has identified numerous processes altered in aging, but how these changes arise is largely unknown. Here we combined nascent RNA sequencing and RNA polymerase II chromatin immunoprecipitation followed by sequencing to elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a913ad7fa4eebcdd778aafb99ee612
https://pure.eur.nl/en/publications/ae5aba47-244e-4ffa-a819-f0d2e785d555
https://pure.eur.nl/en/publications/ae5aba47-244e-4ffa-a819-f0d2e785d555
Autor:
Jeroen Demmers, Jurgen A. Marteijn, Eran Meshorer, Serena T. Bruens, Pernette J. Verschure, Di Zhou, Raghu Ram Edupuganti, Imke K Mandemaker, Dick H. W. Dekkers
Publikováno v:
Journal of Cell Science, 133:jcs235473. Company of Biologists Ltd
Journal of Cell Science, 133(9):jcs235473. Company of Biologists Ltd
Journal of Cell Science, 133(9):jcs235473. Company of Biologists Ltd
Many chromatin remodeling and modifying proteins are involved in the DNA damage response, where they stimulate repair or induce DNA damage signaling. Interestingly, we identified that downregulation of the histone H1 (H1)-interacting protein SET resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d928d1bf76bcc4357cb841c558cc6e1f
https://dare.uva.nl/personal/pure/en/publications/histone-h1-eviction-by-the-histone-chaperone-set-reduces-cell-survival-following-dna-damage(99b1f6c0-4460-4894-8171-bb221c6688f4).html
https://dare.uva.nl/personal/pure/en/publications/histone-h1-eviction-by-the-histone-chaperone-set-reduces-cell-survival-following-dna-damage(99b1f6c0-4460-4894-8171-bb221c6688f4).html
Autor:
Deborah Horst-Kreft, Joyce H.G. Lebbink, Wiggert A. van Cappellen, Dior M. J. M. Beerens, Youri Hoogstrate, Johan W. Mouton, Gert-Jan Kremers, Rob Joosten, John van der Oost, Charlie Laffeber, Duncan J. H. Gaskin, Gaurav Dugar, Rogier Louwen, Jeroen Demmers, Serena T. Bruens, Andrew P. Stubbs, Chinmoy Saha, Maarten Klunder, Peter J. van der Spek, Dik C. van Gent, Prarthana Mohanraju, Peter van Baarlen
Publikováno v:
Science Advances 6 (2020) 25
Science advances, 6(25):eaaz4849. American Association for the Advancement of Science
Science Advances, 6(25)
Science advances, 6(25):eaaz4849. American Association for the Advancement of Science
Science Advances, 6(25)
CRISPR-Cas9 systems are enriched in human pathogenic bacteria and have been linked to cytotoxicity by an unknown mechanism. Here, we show that upon infection of human cells, Campylobacter jejuni secretes its Cas9 (CjeCas9) nuclease into their cytopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac06800930fed35bc446b835458c41d
https://research.wur.nl/en/publications/guide-free-cas9-from-pathogenic-campylobacter-jejuni-bacteria-cau
https://research.wur.nl/en/publications/guide-free-cas9-from-pathogenic-campylobacter-jejuni-bacteria-cau
Autor:
Roland Kanaar, Anja Raams, Dik C. van Gent, Nicolaas G. J. Jaspers, Kishan A. T. Naipal, Jan H.J. Hoeijmakers, Serena T. Bruens, Joris Pothof, Inger Brandsma, Geert J.L.H. van Leenders, Joost L. Boormans, Nicole S. Verkaik
Publikováno v:
PLoS ONE
PLoS One (print), 10(4). Public Library of Science
PLoS ONE, Vol 10, Iss 4, p e0126029 (2015)
PLoS One (print), 10(4). Public Library of Science
PLoS ONE, Vol 10, Iss 4, p e0126029 (2015)
Bladder cancer has a high incidence with significant morbidity and mortality. Attenuated expression of the DNA damage response protein Xeroderma Pigmentosum complementation group C (XPC) has been described in bladder cancer. XPC plays an essential ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f63fad9e0ecd23d4163e1350206ac8
https://pubmed.ncbi.nlm.nih.gov/25927440
https://pubmed.ncbi.nlm.nih.gov/25927440
Autor:
Jan H.J. Hoeijmakers, Erik A.C. Wiemer, Joris Pothof, Pier G. Mastroberardino, Dik C. van Gent, Nicole S. Verkaik, Kasper W.J. Derks, Wytske M. van Weerden, Chiara Milanese, Jiang Chang, Serena T. Bruens, Guido Jenster, Akos Gyenis
Publikováno v:
Cancer Research. 76:1657-1657
Cancer cells that acquire radio-resistance are major problem for treatment outcome. We aimed at identifying mechanisms and networks that control ionizing radiation (IR)-resistance in prostate cancer cells. To this end, we applied to cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27d096658c09200b3d3dbce00d5f9500
https://doi.org/10.1158/1538-7445.am2016-1657
https://doi.org/10.1158/1538-7445.am2016-1657