Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

Autor: Thomas J. Lynch, Georgiana Kuhlmann, Susan L. Boisvert, Leif W. Ellisen, Lecia V. Sequist, Dora Dias-Santagata, Daniel A. Haber, Jeffrey Settleman, Sara Akhavanfard, Kathy Vernovsky, Ultan McDermott, Jeffrey W. Clark, Hannah Stubbs, David N. Louis, Eunice L. Kwak, Serena S. David, Jeffrey A. Engelman, Darrell R. Borger, A. John Iafrate, Steven J. Isakoff

Publikováno v: EMBO Molecular Medicine. 2:146-158

Targeted cancer therapy requires the rapid and accurate identification of genetic abnormalities predictive of therapeutic response. We sought to develop a high-throughput genotyping platform that would allow prospective patient selection to the best

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7be8af29e41171875472d1af5b19cd99
https://doi.org/10.1002/emmm.201000070

Sema4D localizes to synapses and regulates GABAergic synapse development as a membrane-bound molecule in the mammalian hippocampus.

Autor: Raissi AJ; National Center for Behavioral Genomics and Volen Center for Complex Systems, Department of Biology, Brandeis University, Waltham, MA 02454, USA., Staudenmaier EK, David S, Hu L, Paradis S

Publikováno v: Molecular and cellular neurosciences [Mol Cell Neurosci] 2013 Nov; Vol. 57, pp. 23-32. Date of Electronic Publication: 2013 Sep 10.