Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Serena Rinaldo"'
Coordinating energy metabolism and signaling pathways in epithelial self-renewal and differentiation
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Epidermal stem cells (EPSCs) are essential for maintaining skin homeostasis and ensuring a proper wound healing. During in vitro cultivations, EPSCs give rise to transient amplifying progenitors and differentiated cells, finally forming a st
Externí odkaz:
https://doaj.org/article/7be09cfcace941baa12b3bf3a0216e02
Autor:
Ritwik Maity, Xuepei Zhang, Francesca Romana Liberati, Chiara Scribani Rossi, Francesca Cutruzzolá, Serena Rinaldo, Massimiliano Gaetani, José Antonio Aínsa, Javier Sancho
Publikováno v:
eLife, Vol 13 (2024)
Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like Helicobacter pylori, the development of novel therapies is of utmost importance. Understanding the molecular
Externí odkaz:
https://doaj.org/article/8e9d33b85838437486c00c392fcb85a6
Autor:
Sara Di Russo, Francesca Romana Liberati, Agnese Riva, Federica Di Fonzo, Alberto Macone, Giorgio Giardina, Marzia Arese, Serena Rinaldo, Francesca Cutruzzolà, Alessio Paone
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Extravasation is a fundamental step in the metastatic journey, where cancer cells exit the bloodstream and breach the endothelial cell barrier to infiltrate target tissues. The tactics cancer cells employ are sophisticated, closely reflectin
Externí odkaz:
https://doaj.org/article/6955f71b5f474395bbadf1663f02dbc8
Autor:
Chiara Lanzillotta, Antonella Tramutola, Simona Lanzillotta, Viviana Greco, Sara Pagnotta, Caterina Sanchini, Silvia Di Angelantonio, Elena Forte, Serena Rinaldo, Alessio Paone, Francesca Cutruzzolà, Flavia Agata Cimini, Ilaria Barchetta, Maria Gisella Cavallo, Andrea Urbani, D. Allan Butterfield, Fabio Di Domenico, Bindu D. Paul, Marzia Perluigi, Joao M.N. Duarte, Eugenio Barone
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103221- (2024)
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain insulin resistance remain unexplored. Abn
Externí odkaz:
https://doaj.org/article/981f6d63b120410193df144c24aca2cc
Autor:
Elisa Maria Turco, Angela Maria Giada Giovenale, Laura Sireno, Martina Mazzoni, Alessandra Cammareri, Caterina Marchioretti, Laura Goracci, Alessandra Di Veroli, Elena Marchesan, Daniel D’Andrea, Antonella Falconieri, Barbara Torres, Laura Bernardini, Maria Chiara Magnifico, Alessio Paone, Serena Rinaldo, Matteo Della Monica, Stefano D’Arrigo, Diana Postorivo, Anna Maria Nardone, Giuseppe Zampino, Roberta Onesimo, Chiara Leoni, Federico Caicci, Domenico Raimondo, Elena Binda, Laura Trobiani, Antonella De Jaco, Ada Maria Tata, Daniela Ferrari, Francesca Cutruzzolà, Gianluigi Mazzoccoli, Elena Ziviani, Maria Pennuto, Angelo Luigi Vescovi, Jessica Rosati
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-16 (2022)
Abstract Smith-Magenis syndrome (SMS) is a neurodevelopmental disorder characterized by cognitive and behavioral symptoms, obesity, and sleep disturbance, and no therapy has been developed to alleviate its symptoms or delay disease onset. SMS occurs
Externí odkaz:
https://doaj.org/article/3481a3d58ebf491c977d49d933ec8e59
Autor:
Thanalai Poonsiri, Davide Dell’Accantera, Valentina Loconte, Alessandro Casnati, Laura Cervoni, Alessandro Arcovito, Stefano Benini, Alberto Ferrari, Marco Cipolloni, Elisa Cacioni, Francesca De Franco, Nicola Giacchè, Serena Rinaldo, Claudia Folli, Francesco Sansone, Rodolfo Berni, Michele Cianci
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 479 (2023)
Transthyretin (TTR) is an amyloidogenic homotetramer involved in the transport of thyroxine in blood and cerebrospinal fluid. To date, more than 130 TTR point mutations are known to destabilise the TTR tetramer, leading to its extracellular pathologi
Externí odkaz:
https://doaj.org/article/656d5dbbb7e544f2a6912ca4c7534197
Autor:
Alessandra Zevini, Enrico Palermo, Daniele Di Carlo, Magdalini Alexandridi, Serena Rinaldo, Alessio Paone, Francesca Cutruzzola, Marilena P. Etna, Eliana M. Coccia, David Olagnier, John Hiscott
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Dendritic cells (DCs) are important mediators of the induction and regulation of adaptive immune responses following microbial infection and inflammation. Sensing environmental danger signals including viruses, microbial products, or inflammatory sti
Externí odkaz:
https://doaj.org/article/d66c57fed7be4788a8aa5072998ed0b6
Autor:
Michele Monti, Giulia Guiducci, Alessio Paone, Serena Rinaldo, Giorgio Giardina, Francesca Romana Liberati, Francesca Cutruzzolá, Gian Gaetano Tartaglia
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3034-3041 (2021)
Human serine hydroxymethyltransferase (SHMT) regulates the serine-glycine one carbon metabolism and plays a role in cancer metabolic reprogramming. Two SHMT isozymes are acting in the cell: SHMT1 encoding the cytoplasmic isozyme, and SHMT2 encoding t
Externí odkaz:
https://doaj.org/article/e77dbfb8823f40ff9b0b3faaad8e171c
Autor:
Amani Bouzidi, Maria Chiara Magnifico, Alessandro Paiardini, Alberto Macone, Giovanna Boumis, Giorgio Giardina, Serena Rinaldo, Francesca Romana Liberati, Clotilde Lauro, Cristina Limatola, Chiara Lanzillotta, Antonella Tramutola, Marzia Perluigi, Gianluca Sgarbi, Giancarlo Solaini, Alessandra Baracca, Alessio Paone, Francesca Cutruzzolà
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-14 (2020)
Lung cancer is a very aggressive tumor that often forms brain metastases. We show that lung cancer cells motility, fundamental for the formation of metastases, is controlled by amino acids such as serine and glycine, abundant in brain microenvironmen
Externí odkaz:
https://doaj.org/article/4fc13ba560544c24b6d2c73b34ca5f0d
Autor:
Chiara Scribani Rossi, Laura Barrientos-Moreno, Alessio Paone, Francesca Cutruzzolà, Alessandro Paiardini, Manuel Espinosa-Urgel, Serena Rinaldo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4386 (2022)
Bacterial biofilm represents a multicellular community embedded within an extracellular matrix attached to a surface. This lifestyle confers to bacterial cells protection against hostile environments, such as antibiotic treatment and host immune resp
Externí odkaz:
https://doaj.org/article/df57c1bcf362469086d59a7760c2efaf