Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Serena Pulcini"'
Autor:
Paolo Zucca, Marie-Christin Rossmann, Mitja Dodic, Yashwantrao Ramma, Toshiya Matsushima, Steven Seet, Susanne Holtze, Alessandro Bremini, Ingrid Fischinger, Giulia Morosetti, Marcello Sitzia, Roberto Furlani, Oronzo Greco, Giulio Meddi, Paolo Zambotto, Fabiola Meo, Serena Pulcini, Manlio Palei, Gianna Zamaro
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
More than 60% of the 1,700 infectious diseases that affect human come from animals and zoonotic pandemics, after starting from sporadic phenomena limited to rural areas, have become a global emergency. The repeated and frequent zoonotic outbreaks suc
Externí odkaz:
https://doaj.org/article/52da3b7f05844459b2d6e0c7f34f159b
Publikováno v:
Bulletin du Cancer.
Autor:
Jessica O’Neill, Mavis Ayer, Samantha Colhoun, Nicola Daykin, Brenda Hamill, Simone Gabriele, Jordanne Florio, Serena Pulcini, Alison Thomson
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:A28.1-A28
MS is a progressive disease that significantly impacts quality-of-life (QoL).This study aimed to identify unmet disease education and communication needs in people with MS (pwMS) to empower informed decisions, enable self-management and to maintain i
Publikováno v:
Trends in Pharmacological Sciences. 35:4-11
Sarco/endoplasmic reticulum Ca 2+ -ATPases (SERCAs) are increasingly being studied for therapeutic interventions in the fields of cancer, heart disease, and infection. Our suggestion a decade ago that artemisinins (the most important antimalarial cla
Autor:
Rita Tewari, Henry M. Staines, Falgun Shah, Ksenija Slavic, Jon K. Pittman, Jean Halbert, Christian Doerig, Mitchell A. Avery, Richard K. Haynes, Serena Pulcini, Sanjeev Krishna
Publikováno v:
Journal of Infectious Diseases; Vol 208
Background. The mechanism of action of artemisinins against malaria is unclear, despite their widespread use in combination therapies and the emergence of resistance. Results. Here, we report expression of PfATP6 (a SERCA pump) in yeast and demonstra
Publikováno v:
Trends in Parasitology; Vol 26
With the advent of artemisinin resistance, it is timely to revisit the biological basis for the controversial suggestion that this class of antimalarial exerts its activity by inhibiting a calcium ATPase (PfATP6) that is most similar to sarcoplasmic
Autor:
Sanjeev Krishna, Sarah H. Shafik, Manuel Llinás, Daniel A. Daley, Rowena E. Martin, Guillaume Bouyer, Roland A. Cooper, Andrew H. Lee, Lindsey M. Altenhofen, Jianbing Mu, David A. Fidock, Heather J. Painter, Henry M. Staines, Serena Pulcini, Matthew J. Hoke, David J. P. Ferguson, Catherine M. Moore
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2015, 5, pp.14552. ⟨10.1038/srep14552⟩
Scientific Reports, 2015, 5, pp.14552. ⟨10.1038/srep14552⟩
Scientific Reports, Nature Publishing Group, 2015, 5, pp.14552. ⟨10.1038/srep14552⟩
Scientific Reports, 2015, 5, pp.14552. ⟨10.1038/srep14552⟩
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we describe P. falciparum lines subjected to selection by amantadine or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc61042e32f94aeb4b9d4ec2d72240d3
https://hal.sorbonne-universite.fr/hal-01271612/file/srep14552.pdf
https://hal.sorbonne-universite.fr/hal-01271612/file/srep14552.pdf
Publikováno v:
Trends in Parasitology. 27:3-4
Several points are made in the letter by Woodrow and Bustamante [1] regarding our Opinion article on the mechanism of action of artemisinins [2]. The first relates to the relevance of our hypothesis to artemisinin resistance. Whereas there are many p