What Do Adolescents Know About One-Health and Zoonotic Risks? A School-Based Survey in Italy, Austria, Germany, Slovenia, Mauritius, and Japan

Autor: Paolo Zucca, Marie-Christin Rossmann, Mitja Dodic, Yashwantrao Ramma, Toshiya Matsushima, Steven Seet, Susanne Holtze, Alessandro Bremini, Ingrid Fischinger, Giulia Morosetti, Marcello Sitzia, Roberto Furlani, Oronzo Greco, Giulio Meddi, Paolo Zambotto, Fabiola Meo, Serena Pulcini, Manlio Palei, Gianna Zamaro

Publikováno v: Frontiers in Public Health, Vol 9 (2021)

More than 60% of the 1,700 infectious diseases that affect human come from animals and zoonotic pandemics, after starting from sporadic phenomena limited to rural areas, have become a global emergency. The repeated and frequent zoonotic outbreaks suc

Externí odkaz: https://doaj.org/article/52da3b7f05844459b2d6e0c7f34f159b

047 Multiple sclerosis patient perspectives: disease education and communication needs

Autor: Jessica O’Neill, Mavis Ayer, Samantha Colhoun, Nicola Daykin, Brenda Hamill, Simone Gabriele, Jordanne Florio, Serena Pulcini, Alison Thomson

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 93:A28.1-A28

MS is a progressive disease that significantly impacts quality-of-life (QoL).This study aimed to identify unmet disease education and communication needs in people with MS (pwMS) to empower informed decisions, enable self-management and to maintain i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f810963aa194a22f799963a7075677b
https://doi.org/10.1136/jnnp-2022-abn.86

Expression in Yeast Links Field Polymorphisms in PfATP6 to in Vitro Artemisinin Resistance and Identifies New Inhibitor Classes

Autor: Rita Tewari, Henry M. Staines, Falgun Shah, Ksenija Slavic, Jon K. Pittman, Jean Halbert, Christian Doerig, Mitchell A. Avery, Richard K. Haynes, Serena Pulcini, Sanjeev Krishna

Publikováno v: Journal of Infectious Diseases; Vol 208

Background. The mechanism of action of artemisinins against malaria is unclear, despite their widespread use in combination therapies and the emergence of resistance. Results. Here, we report expression of PfATP6 (a SERCA pump) in yeast and demonstra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753835b4772755890cf2a65e9d2de903
https://doi.org/10.1093/infdis/jit171

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities

Autor: Sanjeev Krishna, Sarah H. Shafik, Manuel Llinás, Daniel A. Daley, Rowena E. Martin, Guillaume Bouyer, Roland A. Cooper, Andrew H. Lee, Lindsey M. Altenhofen, Jianbing Mu, David A. Fidock, Heather J. Painter, Henry M. Staines, Serena Pulcini, Matthew J. Hoke, David J. P. Ferguson, Catherine M. Moore

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2015, 5, pp.14552. ⟨10.1038/srep14552⟩
Scientific Reports, 2015, 5, pp.14552. ⟨10.1038/srep14552⟩

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we describe P. falciparum lines subjected to selection by amantadine or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc61042e32f94aeb4b9d4ec2d72240d3
https://hal.sorbonne-universite.fr/hal-01271612/file/srep14552.pdf

More depth of field not wider focus needed

Autor: Henry M. Staines, Sanjeev Krishna, Serena Pulcini, Farrah A Fatih

Publikováno v: Trends in Parasitology. 27:3-4

Several points are made in the letter by Woodrow and Bustamante [1] regarding our Opinion article on the mechanism of action of artemisinins [2]. The first relates to the relevance of our hypothesis to artemisinin resistance. Whereas there are many p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a1d739c21f1f9868eab05855164d430
https://doi.org/10.1016/j.pt.2010.11.001