Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Serena Paladini"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5485 (2024)
Actin filaments, as key components of the cytoskeleton, have aroused great interest due to their numerous functional roles in eukaryotic cells, including intracellular electrical signaling. The aim of this research is to characterize the alternating
Externí odkaz:
https://doaj.org/article/987caa008c7847da91d212a51cbfd363
Autor:
Kira D. A. Rienecker, Katherine Grue, Maria Serena Paladini, Elma S. Frias, Valentina Frattini, Mia C. Borlongan, Austin Chou, Abel Torres-Espin, Karen Krukowski, Adam R. Ferguson, Susanna Rosi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to understand the effects of deep space hazards, including ionizing radiation, confinem
Externí odkaz:
https://doaj.org/article/475ff117d9704584a42f6ab364a9f584
Autor:
Andrea C. Rossetti, Maria Serena Paladini, Cesar Augusto Brüning, Vittoria Spero, Maria Grazia Cattaneo, Giorgio Racagni, Mariusz Papp, Marco A. Riva, Raffaella Molteni
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12453 (2022)
Neuroinflammation has emerged as an important factor in the molecular underpinnings of major depressive disorder (MDD) pathophysiology and in the mechanism of action of antidepressants. Among the inflammatory mediators dysregulated in depressed patie
Externí odkaz:
https://doaj.org/article/fe69fe7334004ca68fdf979eccea3d20
Autor:
Karen Krukowski, Amber Nolan, Elma S Frias, Morgane Boone, Gonzalo Ureta, Katherine Grue, Maria-Serena Paladini, Edward Elizarraras, Luz Delgado, Sebastian Bernales, Peter Walter, Susanna Rosi
Publikováno v:
eLife, Vol 9 (2020)
With increased life expectancy, age-associated cognitive decline becomes a growing concern, even in the absence of recognizable neurodegenerative disease. The integrated stress response (ISR) is activated during aging and contributes to age-related b
Externí odkaz:
https://doaj.org/article/23f8fa0a457740779786e6c53f55676c
Autor:
Andrea Carlo Rossetti, Maria Serena Paladini, Ada Trepci, Anne Mallien, Marco Andrea Riva, Peter Gass, Raffaella Molteni
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
A growing body of evidence supports the close relationship between major depressive disorder (MDD), a severe psychiatric disease more common among women than men, and alterations of the immune/inflammatory system. However, despite the large number of
Externí odkaz:
https://doaj.org/article/f854f6c9b06c4406aedbf4d50a261afa
Autor:
Fabiana Morroni, Giulia Sita, Agnese Graziosi, Gloria Ravegnini, Raffaella Molteni, Maria Serena Paladini, Kris Simone Tranches Dias, Ariele Faria dos Santos, Claudio Viegas, Ihosvany Camps, Letizia Pruccoli, Andrea Tarozzi, Patrizia Hrelia
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Alzheimer’s disease (AD) is the most frequent type of dementia in older people. The complex nature of AD calls for the development of multitarget agents addressing key pathogenic processes. Donepezil, an acetylcholinesterase inhibitor, is a first-l
Externí odkaz:
https://doaj.org/article/5ce18938fa0d4f4798d3c229bc41fda2
Autor:
Paola Brivio, Giulia Sbrini, Giulia Corsini, Maria Serena Paladini, Giorgio Racagni, Raffaella Molteni, Francesca Calabrese
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6261 (2020)
Depression is a recurrent disorder, with about 50% of patients experiencing relapse. Exposure to stressful events may have an adverse impact on the long-term course of the disorder and may alter the response to a subsequent stressor. Indeed, not all
Externí odkaz:
https://doaj.org/article/40230f09b4584938b98f43918384eddc
Autor:
Sharon Liu, Susanna Rosi, Maria Serena Paladini, Elma S. Frias, Nalin Gupta, McKenna Becker, Sonali Gupta, Zoe Boosalis, David Chen, Xi Feng
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Journal of Neuroinflammation
Journal of neuroinflammation, vol 18, iss 1
Journal of Neuroinflammation
Journal of neuroinflammation, vol 18, iss 1
Background Brain-resident microglia have a distinct origin compared to macrophages in other organs. Under physiological conditions, microglia are maintained by self-renewal from the local pool, independent of hematopoietic progenitors. Pharmacologica
Autor:
Elma S. Frias, Mahmood S. Hoseini, Karen Krukowski, Maria Serena Paladini, Katherine Grue, Gonzalo Ureta, Kira D.A. Rienecker, Peter Walter, Michael P. Stryker, Susanna Rosi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 42
Traumatic brain injury (TBI) is a leading cause of long-term neurological disability in the world and the strongest environmental risk factor for the development of dementia. Even mild TBI (resulting from concussive injuries) is associated with a >2-
Autor:
Karen Krukowski, Austin Chou, Xi Feng, Brice Tiret, Maria-Serena Paladini, Lara-Kirstie Riparip, Myriam M. Chaumeil, Cynthia Lemere, Susanna Rosi
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3753 (2018)
Traumatic brain injury (TBI) is of particular concern for the aging community since there is both increased incidence of TBI and decreased functional recovery in this population. In addition, TBI is the strongest environmental risk factor for develop
Externí odkaz:
https://doaj.org/article/64e57aaab6d142c8bf394e5f9321249f