Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Serena Latini"'
Autor:
Serena Latini, Felicita Pedata
Publikováno v:
Journal of Neurochemistry. 79:463-484
Adenosine has several functions within the CNS that involve an inhibitory tone of neurotransmission and neuroprotective actions in pathological conditions. The understanding of adenosine production and release in the brain is therefore of fundamental
Publikováno v:
Annals of the New York Academy of Sciences. 939:74-84
Various experimental approaches have been used to determine the concentration of adenosine in extracellular brain fluid. The cortical cup technique or the microdialysis technique, when adenosine concentrations are evaluated 24 hours after implantatio
Publikováno v:
British Journal of Pharmacology. 140:305-314
1. Ischemic preconditioning in the brain consists of reducing the sensitivity of neuronal tissue to further, more severe, ischemic insults. We recorded field epsps (fepsps) extracellularly from hippocampal slices to develop a model of in vitro ischem
Autor:
Kjell Fuxe, Silvia Ginés, Francisco Ciruela, Serena Latini, Sergi Ferré, Joëlle Hillion, Meritxell Canals, Rafael Franco, Francesca Bordoni, Felicita Pedata, L. F. Agnati, W Staines, Carmen Lluis, Maria Torvinen
Publikováno v:
Neuroscience. 113:709-719
The role of adenosine deaminase in the interactions between adenosine A(1) and dopamine D(1) receptors was studied in a mouse fibroblast cell line stably cotransfected with human D(1) receptor and A(1) receptor cDNAs (A(1)D(1) cells). Confocal laser
Publikováno v:
Synapse. 41:58-64
Previous studies have demonstrated that when the temperature of hippocampal brain slices is increased, there is a corresponding depression of synaptic potentials mediated by an increased activation of presynaptic adenosine A(1) receptors. The present
Publikováno v:
British Journal of Pharmacology. 128:1035-1044
1. In the present study we investigated the role of A2A adenosine receptors in hippocampal synaptic transmission under in vitro ischaemia-like conditions. 2. The effects of adenosine, of the selective A2A receptor agonist, CGS 21680 (2-[p-(2-carboxye
Publikováno v:
British Journal of Pharmacology. 127:729-739
1. The application of an ischaemic insult in hippocampal slices results in the depression of synaptic transmission, mainly attributed to the activation of A1 adenosine receptors by adenosine released in the extracellular space. 2. To estimate the con
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 355:250-255
The role of L-, N- and P-type voltage-dependent calcium channels (VDCCs) in the release of adenosine from rat hippocampal slices was investigated by evaluating the effect of the L-channel activator 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluorometh
Autor:
E. Kawashima, W.R. Proctor, Marta Pazzagli, F. Cattabeni, Felicita Pedata, Claudia Corsi, Serena Latini, G. Buell, Thomas V. Dunwiddie, Maria P. Abbracchio, Lihong Diao, François Rassendren, N. Bischofberger, J.M. Brundege, R. A. North, Annmarie Surprenant, R.C.S. Lin, Ginetta Collo, Kenneth A. Jacobson, Giancarlo Pepeu
Publikováno v:
Scopus-Elsevier
New exciting developments on the occurrence and functional role of purinoceptors in mammalian brain were presented at the session Purinoceptors in the central nervous system chaired by Flaminio Cattabeni and Tom Dunwiddie at the Purines '96 internati
Investigations into the Adenosine Outflow from Hippocampal Slices Evoked by Ischemia-Like Conditions
Publikováno v:
Journal of Neurochemistry. 61:284-289
The characteristics of adenosine and inosine outflow evoked by 5 min of ischemia-like conditions in vitro (superfusion with glucose-free Krebs solution gassed with 95% N2/5% CO2) were investigated on rat hippocampal slices. The viability of the slice