Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Serena Ghisletti"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Inflammation-dependent changes in gene expression programs in innate immune cells, such as macrophages, involve extensive reprogramming of metabolism. This reprogramming is essential for the production of metabolites required for chromatin modificati
Externí odkaz:
https://doaj.org/article/e2486814375541a3976ba281aacc569a
Autor:
Veronica Vallelonga, Francesco Gandolfi, Francesca Ficara, Matteo Giovanni Della Porta, Serena Ghisletti
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2613 (2023)
Inflammation impacts human hematopoiesis across physiologic and pathologic conditions, as signals derived from the bone marrow microenvironment, such as pro-inflammatory cytokines and chemokines, have been shown to alter hematopoietic stem cell (HSCs
Externí odkaz:
https://doaj.org/article/b802d1fa812b4b88a900e473c65a824e
Autor:
Agnese Collino, Alberto Termanini, Paola Nicoli, Giuseppe Diaferia, Sara Polletti, Camilla Recordati, Vittoria Castiglioni, Donatella Caruso, Nico Mitro, Gioacchino Natoli, Serena Ghisletti
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007380 (2018)
Chronic inflammation promotes oncogenic transformation and tumor progression. Many inflammatory agents also generate a toxic microenvironment, implying that adaptive mechanisms must be deployed for cells to survive and undergo transformation in such
Externí odkaz:
https://doaj.org/article/f28327ae537a47b4b48101016d6169bf
Autor:
Laure Escoubet-Lozach, Christopher Benner, Minna U Kaikkonen, Jean Lozach, Sven Heinz, Nathan J Spann, Andrea Crotti, Josh Stender, Serena Ghisletti, Donna Reichart, Christine S Cheng, Rosa Luna, Colleen Ludka, Roman Sasik, Ivan Garcia-Bassets, Alexander Hoffmann, Shankar Subramaniam, Gary Hardiman, Michael G Rosenfeld, Christopher K Glass
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002401 (2011)
Precise control of the innate immune response is required for resistance to microbial infections and maintenance of normal tissue homeostasis. Because this response involves coordinate regulation of hundreds of genes, it provides a powerful biologica
Externí odkaz:
https://doaj.org/article/f69a8d7af71742de8be55e14a6e909d9
Autor:
Francesca De Santa, Iros Barozzi, Flore Mietton, Serena Ghisletti, Sara Polletti, Betsabeh Khoramian Tusi, Heiko Muller, Jiannis Ragoussis, Chia-Lin Wei, Gioacchino Natoli
Publikováno v:
PLoS Biology, Vol 8, Iss 5, p e1000384 (2010)
Mammalian genomes are pervasively transcribed outside mapped protein-coding genes. One class of extragenic transcription products is represented by long non-coding RNAs (lncRNAs), some of which result from Pol_II transcription of bona-fide RNA genes.
Externí odkaz:
https://doaj.org/article/bccdaf22446346fdb514dd8e218aaa18
Publikováno v:
EMBO Rep
Macrophages react to microbial and endogenous danger signals by activating a broad panel of effector and homeostatic responses. Such responses entail rapid and stimulus-specific changes in gene expression programs accompanied by extensive rewiring of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cd18bd0627784e632b6a7035209ffd
https://europepmc.org/articles/PMC8419687/
https://europepmc.org/articles/PMC8419687/
Autor:
Viviana Piccolo, Serena Ghisletti, Marta Russo, Iros Barozzi, Sara Polletti, Gioacchino Natoli, Liv Austenaa, Elena Prosperini, Giuseppe R. Diaferia, Danilo Polizzese
Publikováno v:
Nature structural & molecular biology
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology
Interactions between the splicing machinery and RNA polymerase II increase protein-coding gene transcription. Similarly, exons and splicing signals of enhancer-generated long noncoding RNAs (elncRNAs) augment enhancer activity. However, elncRNAs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c1ee0e04d8cc41972333f8d480a710
https://pubmed.ncbi.nlm.nih.gov/33767452
https://pubmed.ncbi.nlm.nih.gov/33767452
Autor:
Serena Ghisletti, Federico Martello, Claudia Cella, Cristina Lenardi, Simona Argentiere, Paolo Milani
Publikováno v:
Polymer International. 65:792-797
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::479de259e9af74011b75580ff1b9e477
https://doi.org/10.1002/pi.5122
https://doi.org/10.1002/pi.5122
Autor:
Gioacchino Natoli, Alberto Termanini, Paola Nicoli, Camilla Recordati, Agnese Collino, Serena Ghisletti, Giuseppe R. Diaferia, Sara Polletti, Nico Mitro, Donatella Caruso, Vittoria Castiglioni
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007380 (2018)
PLoS Genetics
PLoS Genetics
Chronic inflammation promotes oncogenic transformation and tumor progression. Many inflammatory agents also generate a toxic microenvironment, implying that adaptive mechanisms must be deployed for cells to survive and undergo transformation in such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca74e602a0fe105d532b94369d2e793
http://europepmc.org/articles/PMC5957449?pdf=render
http://europepmc.org/articles/PMC5957449?pdf=render
Autor:
Didier Samuel, Stephanie N. Schauer, Daniel J. Gerhardt, Delphine Rapoud, Paola Nicoli, Michaela Kindlova, Sandra R. Richardson, Ruchi Shukla, Francisco J. Sanchez-Luque, Jamila Faivre, Alexandre Dos Santos, Serena Ghisletti, Patricia E. Carreira, Patricia Gerdes, Adam D. Ewing, Geoffrey J. Faulkner
Publikováno v:
Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (5), pp.639-653. ⟨10.1101/gr.226993.117⟩
Genome Research, Cold Spring Harbor Laboratory Press, 2018, 28 (5), pp.639-653. ⟨10.1101/gr.226993.117⟩
The retrotransposon Long Interspersed Element 1 (LINE-1 or L1) is a continuing source of germline and somatic mutagenesis in mammals. Deregulated L1 activity is a hallmark of cancer, and L1 mutagenesis has been described in numerous human malignancie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95e6561d04d7ec1fa51aeb51723d80b
https://hdl.handle.net/10668/12334
https://hdl.handle.net/10668/12334