Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Serena Bucossi"'
Autor:
Serena Bucossi, Stefania Mariani, Mariacarla Ventriglia, Renato Polimanti, Massimo Gennarelli, Cristian Bonvicini, Patrizio Pasqualetti, Federica Scrascia, Simone Migliore, Fabrizio Vernieri, Paolo M. Rossini, Rosanna Squitti
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Nonceruloplasmin-bound copper (“free”) is reported to be elevated in Alzheimer's disease (AD). In Wilson's disease (WD) Cu-ATPase 7B protein tightly controls free copper body levels. To explore whether the ATP7B gene harbours susceptibility loci
Externí odkaz:
https://doaj.org/article/811c05607cff45a698ad49b3c668c9e1
Autor:
Rosanna Squitti, Claudio Catalli, Laura Gigante, Massimo Marianetti, Mattia Rosari, Stefania Mariani, Serena Bucossi, Gioia Mastromoro, Mariacarla Ventriglia, Ilaria Simonelli, Vincenzo Tondolo, Parminder Singh, Ashok Kumar, Amit Pal, Mauro Rongioletti
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6377
Alzheimer’s disease (AD) is a type of dementia whose cause is incompletely defined. Copper (Cu) involvement in AD etiology was confirmed by a meta-analysis on about 6000 participants, showing that Cu levels were decreased in AD brain specimens, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7dcc51c4335376e24496ab12750f31
https://doi.org/10.3390/ijms24076377
https://doi.org/10.3390/ijms24076377
Autor:
Antonio Picardi, Simone Migliore, Federico Greco, Mariacristina Siotto, Livia Quintiliani, Massimo Marano, Claudia Altamura, Carlo Cosimo Quattrocchi, Fabrizio Vernieri, Rosanna Squitti, Serena Bucossi, Umberto Vespasiani Gentilucci, Laura Scarciolla
Publikováno v:
Metabolic Brain Disease. 30:1445-1452
Dysfunctional metal homeostasis contributes to oxidative stress and neuronal damage. These have been implicated in hepatic encephalopathy pathogenesis. To investigate whether altered metal metabolism is associated with hepatic encephalopathy. Twenty-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72c9ae60461ef899a738ff5bbeee4a4
https://doi.org/10.1007/s11011-015-9721-x
https://doi.org/10.1007/s11011-015-9721-x
Autor:
Mariacarla Ventriglia, Rosanna Squitti, Ilaria Simonelli, Mariacristina Siotto, Fabrizio Vernieri, Serena Bucossi, Silvia Donno, Stefania Mariani
Publikováno v:
International Journal of Neuroscience. 126:354-360
Iron homeostasis appears altered in Parkinson's disease (PD). Recent genetic studies and meta-analyses have produced heterogeneous and inconclusive results. In order to verify the possible role of iron status in PD, we have screened some of the main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b570f05850e17252b20a219f342c4c
https://doi.org/10.3109/00207454.2015.1020113
https://doi.org/10.3109/00207454.2015.1020113
Autor:
Rosanna Squitti, Nicola Antonio Colabufo, Serena Bucossi, Chiara Congiu, Mariacarla Ventriglia, Stefania Mariani, Cristian Bonvicini, Imane Ghafir El Idrissi, Orazio Zanetti, Paolo Maria Rossini, Mauro Rongioletti, Massimo Gennarelli
Meta-analyses show that serum copper non-bound-to-ceruloplasmin (non-Cp-Cu) is higher in patients with Alzheimer’s disease (AD). ATP7B gene variants associate with AD, modulating the size of non-Cp-Cu pool. However, a dedicated genetic study compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b755a117215cf765ccf5d97be3a3aabd
http://hdl.handle.net/11379/489876
http://hdl.handle.net/11379/489876
Publikováno v:
BioMetals. 27:53-64
ATP7B is a copper-transporting ATPase that plays a key role in the regulation of copper homeostasis. Mutations in the ATP7B gene are causative for Wilson's disease, and recent reports have suggested that genetic variants are associated with susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c5733b2c4559038fcdfe97bd1c087f
https://doi.org/10.1007/s10534-013-9686-3
https://doi.org/10.1007/s10534-013-9686-3
Autor:
Laura Trotta, Mariacristina Siotto, Mariacarla Ventriglia, Stefania Mariani, Fabrizio Vernieri, Serena Bucossi, Rosanna Squitti, Francesca Ursini, Antonio Callea, Federica Scrascia, Renato Polimanti
Publikováno v:
Journal of Alzheimer's Disease. 37:453-459
Copper homeostasis abnormalities have been shown to be associated with Alzheimer's disease (AD), possibly by accelerating amyloid-β toxicity and plaque formation. The ATP7B gene plays a key role in controlling body copper balance. Our previous studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecc82ed224481f14bef36ed5e56ea74
https://doi.org/10.3233/jad-130431
https://doi.org/10.3233/jad-130431
Autor:
Serena Bucossi, Laura Trotta, Mariacarla Ventriglia, Stefania Mariani, Mariacristina Siotto, Federica Scrascia, Renato Polimanti, Rosanna Squitti, Fabrizio Vernieri, Paolo Maria Rossini
Publikováno v:
NeuroMolecular Medicine; Vol 15
To understand the role of the key copper-regulating gene, ATP7B, in copper dyshomeostasis associated with Alzheimer’s disease (AD), we analyzed the serum levels of copper, ceruloplasmin and ‘free’ (i.e., non-ceruloplasmin bound) copper in 399 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b012bc7a7d559b4402e03e2012134b7
Autor:
Mariacristina Siotto, Patrizio Pasqualetti, Ilaria Simonelli, Mirca Antenucci, Deborah Caprara, Mariacarla Ventriglia, Mauro Rongioletti, Rosanna Squitti, Paolo Maria Rossini, Rossana Molinario, Serena Bucossi, Stefania Mariani
Publikováno v:
Journal of Alzheimer's disease : JAD. 50(4)
Meta-analyses demonstrate copper involvement in Alzheimer's disease (AD), and the systemic ceruloplasmin status in relation to copper is an emerging issue. To deepen this matter, we evaluated levels of ceruloplasmin concentration, ceruloplasmin activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc249350f616e0511ccff1db0541e09
https://pubmed.ncbi.nlm.nih.gov/26836154
https://pubmed.ncbi.nlm.nih.gov/26836154
Autor:
Mauro Rongioletti, Chiara Congiu, Orazio Zanetti, Rosanna Squitti, Mariacarla Ventriglia, Imane Ghafir El Idrissi, Stefania Mariani, Massimo Gennarelli, Nicola Antonio Colabufo, Serena Bucossi, Cristian Bonvicini, Paolo Maria Rossini
Publikováno v:
Molecular neurobiology. 54(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e3c04220a0226735e08fa1f8c3c147
https://pubmed.ncbi.nlm.nih.gov/26758278
https://pubmed.ncbi.nlm.nih.gov/26758278