Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Serena, Torre"'
Autor:
Corey Kretzmer, Rajagopalan Lakshmi Narasimhan, Rahul Deva Lal, Vincent Balassi, James Ravellette, Ajaya Kumar Kotekar Manjunath, Jesvin Joy Koshy, Marta Viano, Serena Torre, Valeria M. Zanda, Mausam Kumravat, Keith Metelo Raul Saldanha, Harikrishnan Chandranpillai, Ifra Nihad, Fei Zhong, Yi Sun, Jason Gustin, Trissa Borgschulte, Jiajian Liu, David Razafsky
Publikováno v:
Biotechnology and Bioengineering. 119:3632-3646
Autor:
Corey, Kretzmer, Rajagopalan Lakshmi, Narasimhan, Rahul Deva, Lal, Vincent, Balassi, James, Ravellette, Ajaya Kumar, Kotekar Manjunath, Jesvin Joy, Koshy, Marta, Viano, Serena, Torre, Valeria M, Zanda, Mausam, Kumravat, Keith Metelo Raul, Saldanha, Harikrishnan, Chandranpillai, Ifra, Nihad, Fei, Zhong, Yi, Sun, Jason, Gustin, Trissa, Borgschulte, Jiajian, Liu, David, Razafsky
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(12)
Chinese hamster ovary (CHO) cells have been used as the industry standard for the production of therapeutic monoclonal antibodies for several decades. Despite significant improvements in commercial-scale production processes and media, the CHO cell h
Autor:
Rebecca Parker, David Brühlmann, Jonathan Souquet, Tobias Haas, Thomas Vuillemin, Anaïs Muhr, Martin Jordan, Hervé Broly, Serena Torre, Markus Sauer, Fabio La Neve, Blanka Bucsella, Antonio Lembo, Franka Kalman, Jürgen Hemberger
Publikováno v:
Journal of biotechnology. 252
Glycosylation plays a pivotal role in pharmacokinetics and protein physiochemical characteristics. In particular, effector functions including antibody-dependent cell-mediated cytotoxicity (ADCC) can be desired, and it has been described that high-ma