Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Serena, Stadler"'
Autor:
Carlotta Welters, Marthe-Lina Welters, Serena Stadler, Lars Bullinger, Julian Strobel, Holger Hackstein, Arunraj Dhamodaran, Thomas Blankenstein, Leo Hansmann
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
The null allele HLA-C*04:09N differs from HLA-C*04:01 in a frameshift mutation within its cytoplasmic domain, resulting in translation of 32 additional amino acids that are assumed to prevent cell surface expression. However, we recently identified a
Externí odkaz:
https://doaj.org/article/4fa81a24ccfa4645947ca81e05a23c1e
Autor:
Vijay Kumar Singh, Sebastian Werner, Simone Schwalm, Volker Lennerz, Stephanie Ruf, Serena Stadler, Holger Hackstein, Alfred Reiter, Thomas Wölfel, Christine Damm-Welk, Wilhelm Woessmann
Publikováno v:
OncoImmunology, Vol 8, Iss 9 (2019)
The oncoantigen nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) induces cellular and humoral immune responses in patients with NPM-ALK-positive anaplastic large cell lymphoma (ALCL). We characterize the NPM-ALK-specific T-cell responses in a cohor
Externí odkaz:
https://doaj.org/article/1f013a88322d4968a640b20c954c6ba3
Autor:
Atanas G. Atanasov, Ioannis Tentes, Sigurd Krieger, Adryan Fristiohady, Stefan Brenner, Ali Özmen, Serena Stadler, Nicole Huttary, Zsuzsanna Bago-Horvath, Verena M. Dirsch, Robert M. Mader, Liselotte Krenn, Helmut Dolznig, Olivier De Wever, Daniela Milovanovic, Silvio Holzner, Georg Krupitza, Daniel Senfter, Walter Jäger, Chi Huu Nguyen
Publikováno v:
Food and Chemical Toxicology. 111:114-124
Mechanisms how colorectal cancer (CRC) cells penetrate blood micro-vessel endothelia and metastasise is poorly understood. To study blood endothelial cell (BEC) barrier breaching by CRC emboli, an in vitro assay measuring BEC-free areas underneath SW
Autor:
Brigitte Kopp, Philipp Saiko, Nicole Huttary, Waranya Chatuphonprasert, Liselotte Krenn, Verena M. Dirsch, Silvio Holzner, Daniela Milovanovic, Junli Hong, Georg Krupitza, Chi Huu Nguyen, Stefan Brenner, Serena Stadler, Walter Jäger, Adryan Fristiohady, Atanas G. Atanasov
Publikováno v:
International Journal of Oncology. 50:1879-1888
Lymph node metastasis of breast cancer is a clinical marker of poor prognosis. Yet, there exist no therapies targeting mechanisms of intravasation into lymphatics. Herein we report on an effect of the antidyslipidemic drug fenofibrate with vasoprotec
Autor:
Volker Lennerz, Wilhelm Woessmann, Thomas Wölfel, Alfred Reiter, Stephanie Ruf, Christine Damm-Welk, Holger Hackstein, Sebastian Werner, Simone Schwalm, Serena Stadler, Vijay Kumar Singh
Publikováno v:
OncoImmunology
Oncoimmunology
OncoImmunology, Vol 8, Iss 9 (2019)
Oncoimmunology
OncoImmunology, Vol 8, Iss 9 (2019)
The oncoantigen nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) induces cellular and humoral immune responses in patients with NPM-ALK-positive anaplastic large cell lymphoma (ALCL). We characterize the NPM-ALK-specific T-cell responses in a cohor
Autor:
Julia Eichsteininger, Konstantin Alexander Brendel, Helga Schachner, Mira Stadler, Benedikt Giessrigl, Wolfgang M. Schmidt, Oskar Koperek, Daniel Senfter, Chi Huu Nguyen, Georg Krupitza, Walter Jäger, Serena Stadler, Daniela Milovanovic, Zsuzsanna Bago-Horvath, Nicole Huttary, Helmut Dolznig, Brigitte Marian, Robert M. Mader, Stefan Brenner, Sigurd Krieger, Silvio Holzner, Liselotte Krenn, Olivier De Wever
Publikováno v:
CELLULAR AND MOLECULAR LIFE SCIENCES
Retraction of mesenchymal stromal cells supports the invasion of colorectal cancer cells (CRC) into the adjacent compartment. CRC-secreted 12(S)-HETE enhances the retraction of cancer-associated fibroblasts (CAFs) and therefore, 12(S)-HETE may enforc
Autor:
Benedikt Giessrigl, Juliane Riha, Georg Krupitza, Silvio Holzner, Verena M. Dirsch, Danijela Milovanovic, Thomas Szekeres, Atanas G. Atanasov, Helmut Dolznig, Philipp Saiko, Yuanfang Li, Adryan Fristiohardy, Walter Jäger, Nicole Huttary, Stefan Brenner, Ingrid Simonitsch-Klupp, Serena Stadler, Sigurd Krieger, Chi Huu Nguyen
Publikováno v:
Cancer Letters. 380:174-183
Secretion of 12(S)-HETE by breast cancer emboli provokes "circular chemorepellent induced defects" (CCIDs) in the adjacent lymphatic vasculature facilitating their intravasation and lymph node metastasis which determines prognosis. Therefore, elucida
Autor:
Serena Stadler, Stefan Brenner, Nicole Huttary, Sigurd Krieger, Georg Krupitza, Helmut Dolznig, Walter Jäger, Chi Huu Nguyen
Publikováno v:
British Journal of Cancer
Background: The arachidonic acid metabolite 12(S)-HETE is suspected to enhance metastatic spread by inducing cancer cell- and lymph endothelial cell (LEC) motility. However, the molecular mechanisms leading to 12(S)-HETE-triggered cell migration are
Publikováno v:
Cancers
Cancers, Vol 10, Iss 4, p 114 (2018)
Cancers, Vol 10, Iss 4, p 114 (2018)
Patients with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL) mount a humoral and cellular immune response against ALK. More than 90% of children and adolescents with ALK-positive ALCL have detectable anti-ALK antibodi
Autor:
Silvio Holzner, Georg Krupitza, Katharina Viola, Nicole Huttary, Sigurd Krieger, Daniel Senfter, José Basílio, Serena Stadler, Daniela Milovanovic, Ingrid Simonitsch-Klupp, Chi Huu Nguyen, Walter Jäger, Rainer de Martin
Publikováno v:
Oncotarget
RELA, RELB, CREL, NFKB1 and NFKB2, and the upstream regulators NEMO and NIK were knocked-down in lymph endothelial cells (LECs) and in MDA-MB231 breast cancer spheroids to study the contribution of NF-κB in vascular barrier breaching. Suppression of