Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Serena, Lattante"'
Autor:
Gaia Di Timoteo, Andrea Giuliani, Adriano Setti, Martina C. Biagi, Michela Lisi, Tiziana Santini, Alessia Grandioso, Davide Mariani, Francesco Castagnetti, Eleonora Perego, Sabrina Zappone, Serena Lattante, Mario Sabatelli, Dante Rotili, Giuseppe Vicidomini, Irene Bozzoni
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease due to gradual motoneurons (MN) degeneration. Among the processes associated to ALS pathogenesis, there is the formation of cytoplasmic inclusions produced by agg
Externí odkaz:
https://doaj.org/article/fba55743618c4cde8526ef8ffa63acac
Autor:
Emiliano Giardina, Paola Mandich, Roberta Ghidoni, Nicola Ticozzi, Giacomina Rossi, Chiara Fenoglio, Francesco Danilo Tiziano, Federica Esposito, Sabina Capellari, Benedetta Nacmias, Rossana Mineri, Rosa Campopiano, Luana Di Pilla, Federica Sammarone, Stefania Zampatti, Cristina Peconi, Flavio De Angelis, Ilaria Palmieri, Caterina Galandra, Eleonora Nicodemo, Paola Origone, Fabio Gotta, Clarissa Ponti, Roland Nicsanu, Luisa Benussi, Silvia Peverelli, Antonia Ratti, Martina Ricci, Giuseppe Di Fede, Stefania Magri, Maria Serpente, Serena Lattante, Teuta Domi, Paola Carrera, Elisa Saltimbanco, Silvia Bagnoli, Assunta Ingannato, Alberto Albanese, Fabrizio Tagliavini, Raffaele Lodi, Carlo Caltagirone, Stefano Gambardella, Enza Maria Valente, Vincenzo Silani
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionHigh repeat expansion (HRE) alleles in C9orf72 have been linked to both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD); ranges for intermediate allelic expansions have not been defined yet, and clinical interpretati
Externí odkaz:
https://doaj.org/article/48c2074ccdf6430aa36dbc406509d0c2
Autor:
Marika Guerra, Lucia Meola, Serena Lattante, Amelia Conte, Mario Sabatelli, Claudio Sette, Camilla Bernardini
Publikováno v:
Cells, Vol 12, Iss 16, p 2058 (2023)
Researchers studying Amyotrophic Lateral Sclerosis (ALS) have made significant efforts to find a unique mechanism to explain the etiopathology of the different forms of the disease. However, despite several mutations associated with ALS having been d
Externí odkaz:
https://doaj.org/article/9bc3c348660a4baaa8d80e84bf62667a
Autor:
Martina Milani, Eleonora Mammarella, Simona Rossi, Chiara Miele, Serena Lattante, Mario Sabatelli, Mauro Cozzolino, Nadia D’Ambrosi, Savina Apolloni
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background An increasing number of studies evidences that amyotrophic lateral sclerosis (ALS) is characterized by extensive alterations in different cell types and in different regions besides the CNS. We previously reported the upregulation
Externí odkaz:
https://doaj.org/article/a5b50c40000449f88e236763164f249f
Autor:
Francesco Martello, Serena Lattante, Paolo Niccolò Doronzio, Amelia Conte, Giulia Bisogni, Daniela Orteschi, Marco Luigetti, Maria Alessandra Marrucci, Marcella Zollino, Mario Sabatelli, Giuseppe Marangi
Publikováno v:
Stem Cell Research, Vol 62, Iss , Pp 102825- (2022)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that selectively affects motor neurons. In 20% of cases, ALS appears in comorbidity with frontotemporal dementia (FTD). We generated patient-derived-induced Pluripotent Stem Cel
Externí odkaz:
https://doaj.org/article/2f475bb91d774b3dad6f12057bae2464
Autor:
Francesco Martello, Serena Lattante, Paolo Niccolò Doronzio, Amelia Conte, Giulia Bisogni, Daniela Orteschi, Filomena Pirozzi, Mario Sabatelli, Marcella Zollino, Giuseppe Marangi
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102461- (2021)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting upper and lower motor neurons. We generated patient-derived-induced Pluripotent Stem Cells (iPSCs), from an ALS patient affected by an early-onset and aggressive
Externí odkaz:
https://doaj.org/article/09de13cc8c8544ea972ad8fd83227b78
Autor:
Daniele Pollini, Rosa Loffredo, Marina Cardano, Luciano Conti, Serena Lattante, Angelantonio Notarangelo, Mario Sabatelli, Alessandro Provenzani
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 146-150 (2018)
Fibroblasts isolated from an Amyotrophic Lateral Sclerosis (ALS)-patient carrying a mutation in Matrin-3 (p.Q66K -MATR3) gene were reprogrammed to the pluripotency stage by using non-integrating episomal plasmids. We generated the Q66K#44DRM induced
Externí odkaz:
https://doaj.org/article/43ea32276e9c41f0b9f93725601b2c25
Autor:
Angela D'Anzi, Filomena Altieri, Elisa Perciballi, Daniela Ferrari, Barbara Torres, Laura Bernardini, Serena Lattante, Mario Sabatelli, Angelo Luigi Vescovi, Jessica Rosati
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102356- (2021)
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative condition with phenotypic and genetic heterogeneity. It is characterized by the selective vulnerability and the progressive loss of the neural population. Here, an induced pluripot
Externí odkaz:
https://doaj.org/article/98b0bf5db00147a68d97e9c645d39984
Autor:
Elisa Perciballi, Federica Bovio, Jessica Rosati, Federica Arrigoni, Angela D’Anzi, Serena Lattante, Maurizio Gelati, Fabiola De Marchi, Ivan Lombardi, Giorgia Ruotolo, Matilde Forcella, Letizia Mazzini, Sandra D’Alfonso, Lucia Corrado, Mario Sabatelli, Amelia Conte, Luca De Gioia, Sabata Martino, Angelo Luigi Vescovi, Paola Fusi, Daniela Ferrari
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 815 (2022)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of the upper and lower motor neurons (MNs). About 10% of patients have a family history (familial, fALS); however, most patients seem to develop the sp
Externí odkaz:
https://doaj.org/article/c7496b1741b1406ba8c04a056c40302d
Autor:
Romina Durigon, Alice L Mitchell, Aleck WE Jones, Andreea Manole, Mara Mennuni, Elizabeth MA Hirst, Henry Houlden, Giuseppe Maragni, Serena Lattante, Paolo Niccolo’ Doronzio, Ilaria Dalla Rosa, Marcella Zollino, Ian J Holt, Antonella Spinazzola
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 9, Pp 1-20 (2018)
Abstract The diverse clinical phenotypes of Wolf–Hirschhorn syndrome (WHS) are the result of haploinsufficiency of several genes, one of which, LETM1, encodes a protein of the mitochondrial inner membrane of uncertain function. Here, we show that L
Externí odkaz:
https://doaj.org/article/1e9b97c05f204f27bc09bdacc3041823