Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Serena, Deiana"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cognitive flexibility, the ability to adapt to unexpected changes, is critical for healthy environmental and social interactions, and thus to everyday functioning. In neuropsychiatric diseases, cognitive flexibility is often impaired and treatment op
Externí odkaz:
https://doaj.org/article/0752ae49210744ecb8f225c342785b4c
Autor:
null R. Hilton, null Susannah R. Simpson, null Emily R. Sherman, null Will Raby‐Smith, null Keemia Azvine, null Maite Arribas, null Jiaqi Zhou, null Serena Deiana, null Bastian Hengerer, null Emma N. Cahill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4cada3bf898ff0dd9e295bd8363128
https://doi.org/10.1111/ejn.15870/v2/response1
https://doi.org/10.1111/ejn.15870/v2/response1
Autor:
Alexandra Münster, Susanne Sommer, Diana Kúkeľová, Hannes Sigrist, Eliza Koros, Serena Deiana, Klaus Klinder, Tamara Baader-Pagler, Svenja Mayer-Wrangowski, Boris Ferger, Tom Bretschneider, Christopher R. Pryce, Wolfgang Hauber, Moritz von Heimendahl
Apathy, deficiency of motivation including willingness to exert effort for reward, is a common symptom in many psychiatric and neurological disorders, including depression and schizophrenia. Despite improved understanding of the neurocircuitry and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971a314290fac4cecbcef404ff0384c5
https://www.zora.uzh.ch/id/eprint/221202/
https://www.zora.uzh.ch/id/eprint/221202/
Autor:
Joe R. Hilton, Susannah R. Simpson, Emily R. Sherman, Will Raby‐Smith, Keemia Azvine, Maite Arribas, Jiaqi Zhou, Serena Deiana, Bastian Hengerer, Emma N. Cahill
Funder: Boehringer Ingelheim Pharma GmbH & Co. KG
Fear and anxiety are adaptive states that allow humans and animals alike to respond appropriately to threatening cues in their environment. Commonly used tasks for studying behaviour akin to fear
Fear and anxiety are adaptive states that allow humans and animals alike to respond appropriately to threatening cues in their environment. Commonly used tasks for studying behaviour akin to fear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecb84b2e410e1a27566827a2a1fcc8c
https://doi.org/10.1101/2022.03.21.485161
https://doi.org/10.1101/2022.03.21.485161
Autor:
Serena Deiana, Wolfgang Hauber, Alexandra Munster, Susanne Sommer, Boris Ferger, Anelise Marti, Bernhard Schmid, Cornelia Dorner-Ciossek, Holger Rosenbrock
Publikováno v:
European Journal of Pharmacology. 935:175306
N-methyl-D-aspartate-receptor (NMDAR) hypofunction contributes to cognitive impairments in neuropsychiatric disorders such as schizophrenia. Reduced NMDAR signalling can be enhanced by increasing extracellular levels of the NMDAR co-agonist glycine t
Autor:
Anton Pekcec, Birgit Stierstorfer, Cornelia Dorner-Ciossek, Serena Deiana, Holger Rosenbrock, Niklas Schülert
Publikováno v:
British Journal of Pharmacology. 175:3021-3033
Background and purpose Insufficient prefrontal dopamine 1 (D1 ) receptor signalling has been linked to cognitive dysfunction in several psychiatric conditions. Because the PDE1 isoform B (PDE1B) is postulated to regulate D1 receptor-dependent signal
Autor:
Serena Deiana, Erica Zamberletti
Despite schizophrenia being among the most debilitating and costly adult psychiatric disorders, current antipsychotic therapies have limited efficacy and are associated with a high incidence of metabolic and neurological side effects. The search for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b079b518301e097d26983a12a016318d
https://doi.org/10.1016/b978-0-12-804791-0.00014-8
https://doi.org/10.1016/b978-0-12-804791-0.00014-8
Autor:
Jeff K. Abbott, David L. Atkinson, Peter Bosanac, Beth Broussard, John D. Cahill, David J. Castle, Angelo B. Cedeño, Michael T. Compton, Wilson M. Compton, Jose Cortes-Briones, Serena Deiana, Deepak C. D'Souza, Papanti Duccio, Anne Eden Evins, Schifano Fabrizio, Ana Fresán, Jodi M. Gilman, Swapnil Gupta, Beth Han, Orsolini Laura, Ana Lusicic, Marc W. Manseau, Patrick McGorry, Meredith McHugh, Barnaby Nelson, Brian O'Donoghue, Luca Pauselli, Rajiv Radhakrishnan, Claire Ramsay Wan, Rebeca Robles-García, Mohamed Sherif, Sara M. Sobolewski, Nadia Solowij, Carlos-Alfonso Tovilla-Zarate, Erica Zamberletti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39243800504f81b404a177aa383d28b3
https://doi.org/10.1016/b978-0-12-804791-0.09992-4
https://doi.org/10.1016/b978-0-12-804791-0.09992-4
Autor:
Yuki Yamasaki, Gernot Riedel, Tetsuro Kikuchi, Naoki Amada, Akihito Watanabe, Serena Deiana, Colin Stott
Publikováno v:
Behavioural Pharmacology. 26:748-765
Deficiencies in social activities are hallmarks of numerous brain disorders. With respect to schizophrenia, social withdrawal belongs to the category of negative symptoms and is associated with deficits in the cognitive domain. Here, we used the N-me
Autor:
Mandy Magbagbeolu, Serena Deiana, Steve Close, Karsten Stamer, Kathleen A. Harrington, Karima Schwab, John Storey, Valeria Melis, David Horsley, Keith A Goatman, Franz Theuring, Elizabeth Anne Goatman, Silke Dietze, Kathleen Davidson, Claude M. Wischik, Janet Elizabeth Rickard, Gernot Riedel, Charles R. Harrington, Claudia Zabke
Publikováno v:
Behavioural Pharmacology
Given the repeated failure of amyloid-based approaches in Alzheimer's disease, there is increasing interest in tau-based therapeutics. Although methylthioninium (MT) treatment was found to be beneficial in tau transgenic models, the brain concentrati