Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Serdar Alpdogan"'
Publikováno v:
Egyptian Journal of Neurosurgery, Vol 37, Iss 1, Pp 1-7 (2022)
Abstract Background In recent years, smaller-sized (diameter
Externí odkaz:
https://doaj.org/article/b7823761c0184fb68cb481233eeb78dd
Autor:
Jan Niklas Lüke, Felix Neumaier, Serdar Alpdogan, Jürgen Hescheler, Toni Schneider, Walid Albanna, Isha Akhtar-Schäfer
Publikováno v:
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background So far, only indirect evidence exists for the pharmacoresistant R-type voltage-gated Ca2+ channel (VGCC) to be involved in transretinal signaling by triggering GABA-release onto ON-bipolar neurons. This release of inhibitory neuro
Externí odkaz:
https://doaj.org/article/41959b2698284772be943b074ab0f013
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 2, Pp 180-194 (2020)
Externí odkaz:
https://doaj.org/article/29e76923a7644e0a8c6e9c9198619676
Autor:
Maxine Dibué-Adjei, Marcel A. Kamp, Serdar Alpdogan, Etienne E. Tevoufouet, Wolfram F. Neiss, Jürgen Hescheler, Toni Schneider
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 3, Pp 935-947 (2017)
Background/Aims: Lamotrigine (LTG) is a popular modern antiepileptic drug (AED), however, its mechanism of action has yet to be fully understood, as it is known to modulate many members of several ion channel families. In heterologous systems, LTG in
Externí odkaz:
https://doaj.org/article/24caccd8734c49e7b6dc8f88e6355190
Autor:
Walid Albanna, Konstantin Kotliar, Jan Niklas Lüke, Serdar Alpdogan, Catharina Conzen, Ute Lindauer, Hans Clusmann, Jürgen Hescheler, Walthard Vilser, Toni Schneider, Gerrit Alexander Schubert
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204689 (2018)
BACKGROUND:Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Reti
Externí odkaz:
https://doaj.org/article/b6a67b6f17f6459cbecc9015aff549ed
Publikováno v:
Journal of Experimental Neurology. 4:11-20
Objective: This review article describes the characteristics of published literature using the cisterna magna blood injection mouse model of subarachnoid hemorrhage (SAH) with the aim to define particular standards and identify moderators of mortalit
Autor:
Serdar Alpdogan, Timo Sander, Rui Zhang, Dilaware Khan, Xuanchen Li, Huakang Zhou, Ke Li, Ann-Christin Nickel, Baolong Zheng, Anastasiya Skryabin, Simon Schieferdecker, Björn B. Hofmann, Daniel Maximilian Donaldson, Jan Frederick Cornelius, Daniel Hänggi, Sajjad Muhammad
Publikováno v:
Translational Stroke Research.
Robust preclinical models are inevitable for researchers to unravel pathomechanisms of subarachnoidal hemorrhage (SAH). For the mouse perforation model of SAH, the goal of this meta-review was the determination of variances in mortality, SAH severity
Publikováno v:
Pflugers Archiv
So-called pharmacoresistant (R-type) voltage-gated Ca2+ channels are structurally only partially characterized. Most of them are encoded by the CACNA1E gene and are expressed as different Cav2.3 splice variants (variant Cav2.3a to Cav2.3e or f) as th
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 2, Pp 180-194 (2020)
BACKGROUND/AIMS Still in 1999 the first hints were published for the pharmacoresistant Cav2.3 calcium channel to be involved in the generation of epileptic seizures, as transcripts of alpha1E (Cav2.3) and alpha1G (Cav3.1) are changed in the brain of
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
The mating of 77 heterozygous pairs (Cav3.2[+|−] x Cav3.2[+|−]) revealed a significant deviation of genotype distribution from Mendelian inheritance in weaned pups. The mating of 14 pairs (Cav3.2[−|−] female x Cav3.2[+|−] male) and 8 pairs