Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Serdar Durdagi"'
Autor:
Fulya Koksalar Alkan, Ahmet Burak Caglayan, Hilmi Kaan Alkan, Elayne Benson, Yunus Emre Gunduz, Ozge Sensoy, Serdar Durdagi, Elbrus Zarbaliyev, Greg Dyson, Hadeel Assad, Austin Shull, Ahmed Chadli, Huidong Shi, Gurkan Ozturk, Hasan Korkaya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Triple negative breast cancer (TNBC) subtype is characterized with higher EMT/stemness properties and immune suppressive tumor microenvironment (TME). Women with advanced TNBC exhibit aggressive disease and have limited treatment options. Al
Externí odkaz:
https://doaj.org/article/4c7feb8b8c1e4a10878a6afdd1f9525f
Autor:
Kübra Kahveci, Mustafa Barbaros Düzgün, Abdullah Emre Atis, Abdullah Yılmaz, Aida Shahraki, Basak Coskun, Serdar Durdagi, Necla Birgul Iyison
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Currently, there is no pesticide available for the selective control of the pine processionary moth (Thaumetopoea pityocampa-specific), and conventional methods typically rely on mechanical techniques such as pheromone traps or broad-spectru
Externí odkaz:
https://doaj.org/article/6aa471dc5aa149aa8f0e9219d4ea93f0
Publikováno v:
ACS Omega, Vol 8, Iss 43, Pp 40864-40877 (2023)
Externí odkaz:
https://doaj.org/article/66222584b4c94fb0b7066f220167d4a7
Autor:
Panagiou Mavroeidi, Leandros P. Zorba, Nikolaos V. Tzouras, Stavros P. Neofotistos, Nikitas Georgiou, Kader Sahin, Murat Şentürk, Serdar Durdagi, Georgios C. Vougioukalakis, Thomas Mavromoustakos
Publikováno v:
Molecules, Vol 29, Iss 11, p 2486 (2024)
A versatile family of quaternary propargylamines was synthesized employing the KA2 multicomponent reaction, through the single-step coupling of a number of amines, ketones, and terminal alkynes. Sustainable synthetic procedures using transition metal
Externí odkaz:
https://doaj.org/article/84f8841a1168464e927770c6a6976733
Autor:
Seyma Calis, Berna Dogan, Serdar Durdagi, Asuman Celebi, Ozlem Yapicier, Turker Kilic, Eda Tahir Turanli, Timucin Avsar
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Anti-apoptotic members of the Bcl-2 family proteins play central roles in the regulation of cell death in glioblastoma (GBM), the most malignant type of brain tumor. Despite the advances in GBM treatment, there is still an urgent need for ne
Externí odkaz:
https://doaj.org/article/1572c5b11494469fa14f9d1429dfa998
Autor:
Huseyin Tunc, Berna Dogan, Büşra Nur Darendeli Kiraz, Murat Sari, Serdar Durdagi, Seyfullah Kotil
Publikováno v:
PeerJ, Vol 11, p e14987 (2023)
Drug resistance is a primary barrier to effective treatments of HIV/AIDS. Calculating quantitative relations between genotype and phenotype observations for each inhibitor with cell-based assays requires time and money-consuming experiments. Machine
Externí odkaz:
https://doaj.org/article/72484c17117c4bc182dffdd6ae581f48
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 925-936 (2022)
Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies have shown that they increased
Externí odkaz:
https://doaj.org/article/39b8408e73004486b905e5b057884f2f
Autor:
Huseyin Cavdar, Murat Senturk, Murat Guney, Serdar Durdagi, Gulru Kayik, Claudiu T. Supuran, Deniz Ekinci
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 429-437 (2019)
Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) inhibitors are interesting compounds for different therapeutic applications, among which Alzheimer’s disease. Here, we investigated the inhibition of these cholinesterases with uracil de
Externí odkaz:
https://doaj.org/article/784ec375b5d14723b3802f7ed92de447
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Antiapoptotic members of B-cell leukemia/lymphoma-2 (BCL-2) family proteins are one of the overexpressed proteins in cancer cells that are oncogenic targets. As such, targeting of BCL-2 family proteins raises hopes for new therapeutic discoveries. Th
Externí odkaz:
https://doaj.org/article/d6d913ea9c3143c1a13f3237452571d3
Publikováno v:
Current Medicinal Chemistry. 29:5925-5948
Abstract: The COVID-19 outbreak caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to have high incidence and mortality rate globally. To meet the increasingly growing demand for new therapeutic drugs and vaccines, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1ce0a18c10755b3690524e332efbf4b
https://doi.org/10.2174/0929867329666220627121416
https://doi.org/10.2174/0929867329666220627121416