Association of Rho-kinase Gene Polymorphisms with Respiratory Distress Syndrome in Preterm Neonates

Autor: Gül Kaya, Ercan Sivasli, Serdar Oztuzcu, Nuriye A. Melekoglu, Esma Ozkara, Unal Sarikabadayi, Abdullah T. Demiryürek

Publikováno v: Pediatrics and Neonatology, Vol 58, Iss 1, Pp 36-42 (2017)

Respiratory distress syndrome (RDS) of the newborn is one of the most common causes of morbidity and mortality in preterm infants. Our objective was to determine the association between Rho-kinase (ROCK1 and ROCK2) gene polymorphisms and RDS in prete

Externí odkaz: https://doaj.org/article/798416163d8647f5984c3a0673b4c62c

IMPORTANCE OF HYPERBILURUBINEMIA IN DIFFERENTIATION OF PRIMARY AND SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN PEDIATRIC CASES

Autor: seval ozen, alper Dai, enes coskun, serdar oztuzcu, sercan ergun, elif aktekin, sibel yavuz, Ali Bay

Publikováno v: Mediterranean Journal of Hematology and Infectious Diseases, Vol 6, Iss 1, Pp e2014067-e2014067 (2014)

Background and objective: Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hyper inflammatory disease. It is difficult to differentiate between primary and secondary HLH based on clinical findings at the onset of disease. We aimed to fi

Externí odkaz: https://doaj.org/article/1f03746a2d4b415fbde5a62ddb2413b8

The distribution of circulating microRNA and their relation to coronary disease [v1; ref status: indexed, http://f1000r.es/SZ9aqM]

Autor: Jane E Freedman, Bahadir Ercan, Kristine M Morin, Ching-Ti Liu, Lulufer Tamer, Lokman Ayaz, Mehmet Kanadasi, Dilek Cicek, Ali Ihsan Seyhan, Rabia Eker Akilli, Celalettin Camci, Beyhan Cengiz, Serdar Oztuzcu, Kahraman Tanriverdi

Publikováno v: F1000Research, Vol 1 (2012)

Background: MicroRNAs (miRNAs) are small RNAs that regulate gene expression by suppressing protein translation and may influence RNA expression. MicroRNAs are detected in extracellular locations such as plasma; however, the extent of miRNA expression

Externí odkaz: https://doaj.org/article/2b9bbcd42fdc4a3299a6ca3d52e81f81

Investigation of Distribution of Beta -Thalassemia Hereditary Mutations in Gaziantep and the Surrounding Areas

Autor: Sinan Akbayram, Ali Bay, Elif Aktekin, Mustafa Ulasli, Füsun Taşgül, Serdar Oztuzcu, Ahmet Arslan, Gülper Nacarkahya, Murat Korkmaz

Publikováno v: Journal of Clinical and Experimental Investigations, Vol 7, Iss 4, Pp 265-268 (2016)
Volume: 7, Issue: 4 265-268
Journal of Clinical and Experimental Investigations

Introduction: Beta-thalassemia is the most common autosomal recessive disease. More than 200 differentmutations determined in beta-globin gene. Beta thalassemia disease has a severe clinical picture. Treatment of thediseases should be maintained prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9e092925ab2310a779c32b705d8eac
http://jceionline.org/upload/sayi/33/JCEI-01399.pdf

Sequence-based analysis of 5′UTR and coding regions of CASP3 in terms of miRSNPs and SNPs in targetting miRNAs

Autor: Serdar Oztuzcu, Sercan Ergun

Publikováno v: Computational Biology and Chemistry. 62:70-74

Display OmittedPolymorphisms in miRNA genes or miRNA target sites (miRSNPs) can change miRNA activity. Many researches have revealed that SNPs in miRNA target sites improve or decrease the efficacy of the interaction between miRNAs and their target g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bead20c671588367cce540b261fdaf8
https://doi.org/10.1016/j.compbiolchem.2016.04.003