Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Serap Erkek-Ozhan"'
Autor:
Perihan Yagmur Guneri-Sozeri, Gülden Özden-Yılmaz, Asli Kisim, Ece Cakiroglu, Aleyna Eray, Hamdiye Uzuner, Gökhan Karakülah, Devrim Pesen-Okvur, Serif Senturk, Serap Erkek-Ozhan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
The transcription factors FRA1 and FLI1 regulate cell migration and cell junction organization genes in muscle-invasive bladder cancer, and loss of these factors reduces cancer cell invasion, pointing toward a therapeutic avenue.
Externí odkaz:
https://doaj.org/article/e4c1a871085b4d33bd8ef8066b1d2292
Autor:
Gülden Özden-Yılmaz, Busra Savas, Ahmet Bursalı, Aleyna Eray, Alirıza Arıbaş, Serif Senturk, Ezgi Karaca, Gökhan Karakülah, Serap Erkek-Ozhan
Publikováno v:
Cells, Vol 12, Iss 6, p 836 (2023)
Epigenetic deregulation is a critical theme which needs further investigation in bladder cancer research. One of the most highly mutated genes in bladder cancer is KDM6A, which functions as an H3K27 demethylase and is one of the MLL3/4 complexes. To
Externí odkaz:
https://doaj.org/article/6f40010068f14d7099c558314aeb9bfc
Autor:
Gizem Ozgun, Tutku Yaras, Nick Landman, Gökhan Karakülah, Maarten van Lohuizen, Serif Senturk, Serap Erkek Ozhan
Emerging evidence has highlighted the importance of targeting EZH2 in bladder cancer owing to the highly mutated nature of bladder cancers harboring mutations in chromatin regulatory genes opposing Polycomb-mediated repression. Besides, enhanced expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b7d12fcd5bb3f99f5237922e5318621
https://doi.org/10.1101/2023.04.19.537500
https://doi.org/10.1101/2023.04.19.537500
Publikováno v:
Molecular Biology Reports. 49:3135-3147
Background Recent genome-wide studies revealed the molecular subtypes and mutational landscape of bladder cancer, which is the 10th most common cancer causing many deaths. ELF3 is one of the frequently mutated genes in bladder cancer with 14% alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940511749d389f935262accbb6733d18
https://doi.org/10.1007/s11033-022-07145-2
https://doi.org/10.1007/s11033-022-07145-2
Autor:
Fatma Aybuke Mazi, Ece Cakiroglu, Merve Uysal, Minenur Kalyoncu, Dilara Demirci, Perihan Yagmur Guneri Sozeri, Gulden Ozden Yilmaz, Serap Erkek Ozhan, Serif Senturk
Publikováno v:
Cellular Signalling. 105:110611
TGF-beta signaling mediates its biological effects by engaging canonical Smad proteins and crosstalking extensively with other signaling networks, including the NF-kB pathway. The paracaspase MALT1 is an intracellular signaling molecule essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159fcdca6fa6e0dd7a6a9cef4bb891f7
https://doi.org/10.1016/j.cellsig.2023.110611
https://doi.org/10.1016/j.cellsig.2023.110611
Retinoic acid (RA) signaling is a crucial developmental pathway involved in urothelium development, differentiation and regeneration. Deregulation of the RA signaling is highly implicated in several cancers, including bladder cancer, underlying the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e037321b3df59d7db7ceb2e91c00af
https://avesis.deu.edu.tr/publication/details/dc90ab5f-297e-4442-9416-262c7e20fb2e/oai
https://avesis.deu.edu.tr/publication/details/dc90ab5f-297e-4442-9416-262c7e20fb2e/oai