Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Serap, Erdogmus"'
Autor:
Serap Erdogmus, Axel R. Concepcion, Megumi Yamashita, Ikjot Sidhu, Anthony Y. Tao, Wenyi Li, Pedro P. Rocha, Bonnie Huang, Ralph Garippa, Boram Lee, Amy Lee, Johannes W. Hell, Richard S. Lewis, Murali Prakriya, Stefan Feske
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The function of voltage-gated calcium channels in T cells is not well understood and controversial. Here the authors report that a regulatory beta subunit of voltage-gated calcium channels regulates T cell function despite no evidence that these chan
Externí odkaz:
https://doaj.org/article/5b75fb8dc4614e899839c3361f59e74d
Autor:
Serap Erdogmus, Ursula Storch, Laura Danner, Jasmin Becker, Michaela Winter, Nicole Ziegler, Angela Wirth, Stefan Offermanns, Carsten Hoffmann, Thomas Gudermann, Michael Mederos y Schnitzler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
GPCRs are versatile cellular sensors for chemical stimuli but the molecular mechanisms underlying mechanically induced GPCR activation have remained elusive. Here authors identify the C-terminal helix 8 (H8) as the essential structural motif endowing
Externí odkaz:
https://doaj.org/article/9fd1442d78534dbea5f8633d29b4f407
Autor:
Serap, Erdogmus, Axel R, Concepcion, Megumi, Yamashita, Ikjot, Sidhu, Anthony Y, Tao, Wenyi, Li, Pedro P, Rocha, Bonnie, Huang, Ralph, Garippa, Boram, Lee, Amy, Lee, Johannes W, Hell, Richard S, Lewis, Murali, Prakriya, Stefan, Feske
Publikováno v:
Nature communications. 13(1)
TCR stimulation triggers Ca
Autor:
Thomas Gudermann, Ursula Storch, Stefan Offermanns, Laura Danner, Jasmin Becker, Angela Wirth, Nicole Ziegler, Michael Mederos y Schnitzler, Michaela Winter, Serap Erdogmus, Carsten Hoffmann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
G-protein coupled receptors (GPCRs) are versatile cellular sensors for chemical stimuli, but also serve as mechanosensors involved in various (patho)physiological settings like vascular regulation, cardiac hypertrophy and preeclampsia. However, the m
Autor:
Serap Erdogmus, Thomas Gudermann, Ursula Storch, Alexander Dietrich, Susanne Fiedler, Michael Mederos y Schnitzler
Publikováno v:
Molecular Pharmacology. 96:90-98
Although the overall structure of many classical transient receptor potential proteins (TRPC), including human and murine TRPC6, were recently resolved by cryoelectron microscopy analysis, structural changes during channel activation by 1-oleoyl-1-ac
Autor:
Carsten Hoffmann, Laura Danner, Nicole Ziegler, Jasmin Becker, Stefan Offermanns, Angela Wirth, Serap Erdogmus, Michaela Winter, Michael Mederos y Schnitzler, Thomas Gudermann, Ursula Storch
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Ursula, Storch, Julie, Straub, Serap, Erdogmus, Thomas, Gudermann, Michael, Mederos Y Schnitzler
Publikováno v:
Pflugers Archiv
Analysis of G-protein-coupled receptor (GPCR) signaling, in particular of the second messenger cAMP that is tightly controlled by Gs- and Gi/o-proteins, is a central issue in biomedical research. The classical biochemical method to monitor increases
Autor:
Ursula, Storch, Julie, Straub, Serap, Erdogmus, Thomas, Gudermann, Michael, Mederos Y Schnitzler
Publikováno v:
Pflugers Archiv : European journal of physiology. 469(5-6)
Analysis of G-protein-coupled receptor (GPCR) signaling, in particular of the second messenger cAMP that is tightly controlled by G
Autor:
Manuel Gregoritza, Maximilian Philipp, Ursula Storch, Michael Mederos y Schnitzler, Serap Erdogmus, Thomas Gudermann, Franziska Pardatscher, Anna-Lena Forst
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 114, E37-E46 (2017)
The activation mechanism of the classical transient receptor potential channels TRPC4 and -5 via the G(q/11) protein-phospholipase C (PLC) signaling pathway has remained elusive so far. In contrast to all other TRPC channels, the PLC product diacylgl
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 469:1231-1232