Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ser-Mien Chia"'
Autor:
Daniel Metzger, Charlene Zhi Lin Ong, Asad Abu Bakar Ali, Chen Fei Lee, Antong Chen, Chih-Liang Chin, Joana Galvao, Weiwei Luo, Eric Gifford, Ser Mien Chia
Publikováno v:
Medical Imaging: Image Processing
In pharmaceutical research, optical coherence tomography (OCT) has been used for the assessment of diseases such as age-related macular degeneration (AMD) and retinal pigment epithelial (RPE) atrophy on animals in pre-clinical studies. To measure the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39f643ddd30b6f5b897c316122c0893e
https://doi.org/10.1117/12.2549442
https://doi.org/10.1117/12.2549442
Autor:
Pan Lingzhen, Li Gong, Stacey L. Conarello, Ser Mien Chia, Sarah Tiu, Sairam Bellum, Wen Zeng, Chih-Liang Chin, Chen Fei Lee, Lewis Hong, Nina X. Li, Asad Abu Bakar Ali
Publikováno v:
Diabetes. 68
Diabetic macular edema (DME) is one manifestation of diabetic retinopathy (DR), where fluids leak from the retinal vessels into the centre of the macula, causing swelling and blurred vision. VEGF inhibitors (e.g., ranibizumab), have demonstrated clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8379d4d8931c09d1b74f1c2ebf0333fb
https://doi.org/10.2337/db19-35-lb
https://doi.org/10.2337/db19-35-lb
Autor:
Chih-Liang Chin, Pan Lingzhen, Ser Mien Chia, Li Gong, Sarah Tiu, Sarayu Parimal Annamalai, Wen Zeng, Lewis Hong, Nina X. Li, Asad Abu Bakar Ali
Publikováno v:
Diabetes. 67
Diabetic retinopathy (DR) is a diabetic complication involving damages to blood vessels in the retina that, if left untreated, can lead to blindness. It is estimated that over 93 million people suffer from DR worldwide and in fact the disease account
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a9887018974c2858dd09c0179b8600
https://doi.org/10.2337/db18-35-lb
https://doi.org/10.2337/db18-35-lb
Publikováno v:
Journal of Cellular Physiology. 228:393-401
Hepatocyte growth factor (HGF) ameliorates experimental liver fibrosis through many mechanisms, including degradation of accumulated collagen and decreased expression of fibrotic genes. Investigating an upstream mechanism in which HGF could decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fe6a0546a342b6cc543d0046dc9bb3
https://doi.org/10.1002/jcp.24143
https://doi.org/10.1002/jcp.24143
Publikováno v:
Journal of Biological Chemistry. 281:33621-33634
Kinectin is an integral membrane protein with many isoforms primarily found on the endoplasmic reticulum. It has been found to bind kinesin, Rho GTPase, and translation elongation factor-1delta. None of the existing models for the quaternary organiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893d40010f59756a053b45d4cb5707dc
https://doi.org/10.1074/jbc.m607555200
https://doi.org/10.1074/jbc.m607555200
Autor:
Hai-Quan Mao, Hong-Fang Lu, Hanry Yu, Ser-Mien Chia, Wei Seng Lim, Peng-Chi Zhang, Kam W. Leong
Publikováno v:
Tissue Engineering. 11:1667-1677
To overcome the limitations of long-term expression of highly differentiated hepatocyte functions, we have developed a novel bioreactor in which hepatocytes are seeded in a ligand-immobilized hollow fiber cartridge. Galactosylated Pluronic polymer is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4469c350d1c8bda1d7cf2fecc6a850b
https://doi.org/10.1089/ten.2005.11.1667
https://doi.org/10.1089/ten.2005.11.1667
Autor:
Mah-Lee Ng, Chao Yin, Pao-Chun Lin, Cho-Hong Goh, C. H. Quek, Hanry Yu, Hai-Quan Mao, Kam W. Leong, Ser-Mien Chia, Xi Xu
Publikováno v:
Journal of Biotechnology. 118:434-447
Tissue engineering involves ex vivo seeding of anchorage-dependent mammalian cells onto scaffolds, or transplanting cells in vivo. The cell expansion currently requires repeated cell detachment from solid substrata by enzymatic, chemical or mechanica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2317a33a6396683d740be737e0cae83b
https://doi.org/10.1016/j.jbiotec.2005.05.012
https://doi.org/10.1016/j.jbiotec.2005.05.012
Autor:
Yingnan Wu, Jian-Hang Zhu, Susanne Ng, Hanry Yu, Zi-Zong Ho, Yier Toh, Yi Zhou, Ser-Mien Chia, Hai-Quan Mao
Publikováno v:
Biomaterials. 26:3153-3163
Hepatocytes are anchorage-dependent cells sensitive to microenvironment; the control of the physicochemical properties of the extra-cellular matrices may be useful to the maintenance of hepatocyte functions in vitro for various applications. In a mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b2729ef8fe6846cef7e6e1893e964
https://doi.org/10.1016/j.biomaterials.2004.08.017
https://doi.org/10.1016/j.biomaterials.2004.08.017
Autor:
Peng-Chi Zhang, Ser-Mien Chia, Jun Wang, Hanry Yu, Zhi-Qun Tang, Wei Seng Lim, Hai-Quan Mao, Kam W. Leong, Hong-Fang Lu
Publikováno v:
Biomaterials. 24:4893-4903
One of the major challenges in BLAD design is to develop functional substrates suitable for hepatocyte attachment and functional maintenance. In the present study, we designed a poly(vinylidene difluoride) (PVDF) surface coated with galactose-tethere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3e5334fc280338eb957050166c57ff
https://doi.org/10.1016/s0142-9612(03)00404-6
https://doi.org/10.1016/s0142-9612(03)00404-6
Publikováno v:
Biomaterials. 24:1771-1780
Packed-bed or fluidized-bed bioreactor filled with microencapsulated hepatocytes has been proposed as one of the promising designs for bioartificial liver assist device (BLAD) because of potential advantages of high mass transport rate and optimal mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9b2603acc1b99849b1856270969f0f
https://doi.org/10.1016/s0142-9612(02)00580-x
https://doi.org/10.1016/s0142-9612(02)00580-x