Bioengineering bacterial encapsulin nanocompartments as targeted drug delivery system

Autor: Kenth Gustafsson, Rana Khalife, Konstantin Pildish, Rupali Dabas, Sofia Esteban Serna, Vladimir Kalinovskiy, Noelle Colant, Matas Deveikis, Alexander Van de Steen, Saverio Charalambous, Hasan Mustafa Khan, Stefanie Frank, Clare M. Robinson, Diana A. Catana

Publikováno v: Synthetic and Systems Biotechnology, Vol 6, Iss 3, Pp 231-241 (2021)
Synthetic and Systems Biotechnology

The development of Drug Delivery Systems (DDS) has led to increasingly efficient therapies for the treatment and detection of various diseases. DDS use a range of nanoscale delivery platforms produced from polymeric of inorganic materials, such as mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89d5763f69c5fb3ee6055a67c29ad2d
http://www.sciencedirect.com/science/article/pii/S2405805X21000442

Catalytic Dyad in the SGNH Hydrolase Superfamily: In-depth Insight into Structural Parameters Tuning the Catalytic Process of Extracellular Lipase from Streptomyces rimosus

Autor: Zoran Štefanić, Robert Vianello, Biserka Kojić-Prodić, Ivana Leščić Ašler, Aleksandra Maršavelski

Publikováno v: ACS Chemical Biology. 12:1928-1936

SrLip is an extracellular enzyme from Streptomyces rimosus (Q93MW7) exhibiting lipase, phospholipase, esterase, thioesterase, and tweenase activities. The structure of SrLip is one of a very few lipases, among the 3D-structures of the SGNH superfamil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e95aa693fd6697f301891e73ad79974
https://doi.org/10.1021/acschembio.6b01140

Open questions in origin of life: experimental studies on the origin of nucleic acids and proteins with specific and functional sequences by a chemical synthetic biology approach

Autor: Pier Luigi Luisi, Fabrizio Anella, Rafal Wieczorek, Katarzyna P. Adamala, Cristiano Chiarabelli, Pasquale Stano

Publikováno v: Computational and Structural Biotechnology Journal, 9 (14), 2014
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 9, Iss 14, Pp 1-10 (2014)
Adamala, K, Anella, F, Wieczorek, R, Stano, P, Chiarabelli, C & Luisi, P L 2014, ' Open questions in origin of life: experimental studies on the origin of nucleic acids and proteins with specific and functional sequences by a chemical synthetic biology approach ', Computational and Structural Biotechnology Journal, vol. 9, no. 14, e201402004 . https://doi.org/10.5936/csbj.201402004

In this mini-review we present some experimental approaches to the important issue in the origin of life, namely the origin of nucleic acids and proteins with specific and functional sequences. The formation of macromolecules on prebiotic Earth faces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806f6643dfdca25018771482dac449af
https://hdl.handle.net/11590/134125

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