Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ser, Serine"'
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Autor:
Jie Zan, Bi Wang, Xuya Zhao, Xiya Deng, Hongda Ding, Zijing Wei, Shuai Wang, Zhi Huang, Minyi Lu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 465-487 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Hepatocellular carcinoma (HCC) is the most common type of hepatic malignancies, with poor prognosis and low survival rate. Paraspeckles, which are unique subnuclear structures, are recently found to be involved in the development of
Autor:
Prem Rajak, Sumedha Roy, Achintya Kumar Pal, Manas Paramanik, Moumita Dutta, Sayanti Podder, Saurabh Sarkar, Abhratanu Ganguly, Moutushi Mandi, Anik Dutta, Kanchana Das, Siddhartha Ghanty, Salma Khatun
Publikováno v:
Current Research in Toxicology, Vol 2, Iss, Pp 411-423 (2021)
Current Research in Toxicology
CURRENT RESEARCH IN TOXICOLOGY
Current Research in Toxicology
CURRENT RESEARCH IN TOXICOLOGY
Graphical abstract
Highlights • Inhalation of rotenone exposes lung surfactant proteins (SP) to this pesticide. • SP-A and SP-D provides protection from microbial infection. • SP-B and SP-C maintain structure and respiratory function of lu
Highlights • Inhalation of rotenone exposes lung surfactant proteins (SP) to this pesticide. • SP-A and SP-D provides protection from microbial infection. • SP-B and SP-C maintain structure and respiratory function of lu
Publikováno v:
The Journal of Biological Chemistry
WHIM syndrome is a rare immunodeficiency disorder that is characterized by warts, hypogammaglobulinemia, infections, and myelokathexis. While several gain-of-function mutations that lead to C-terminal truncations, frame shifts and point mutations in
Autor:
Kavita Bhagat, Preet Mohinder Singh Bedi, Atamjit Singh, Amit Duggal, Puja Gulati, Komalpreet Kaur, Shilpa Dudhal, Harmandeep Kaur Gulati, Jatinder Vir Singh, Jaspreet Kaur, Harbinder Singh, Nitish Kumar
Publikováno v:
Phytomedicine Plus
Phytomedicine Plus, Vol 1, Iss 4, Pp 100083-(2021)
Phytomedicine Plus, Vol 1, Iss 4, Pp 100083-(2021)
Background Lack of treatment of novel Coronavirus disease led to the search of specific antivirals that are capable to inhibit the replication of the virus. The plant kingdom has demonstrated to be an important source of new molecules with antiviral
Autor:
Pauli Puolakkainen, Antti Kuuliala, Krista Kuuliala, Antti Turunen, Leena Kylänpää, Harri Mustonen
Publikováno v:
Pancreas
Objectives Clinical practice lacks biomarkers to predict the severity of acute pancreatitis (AP). We studied if intracellular signaling of circulating leukocytes could predict persistent organ dysfunction (OD) and secondary infections in AP. Methods
Autor:
Hangel, Gilbert, Cadrien, Cornelius, Lazen, Philipp, Furtner, Julia, Lipka, Alexandra, Hečková, Eva, Hingerl, Lukas, Motyka, Stanislav, Gruber, Stephan, Strasser, Bernhard, Kiesel, Barbara, Mischkulnig, Mario, Preusser, Matthias, Roetzer, Thomas, Wöhrer, Adelheid, Widhalm, Georg, Rössler, Karl, Trattnig, Siegfried, Bogner, Wolfgang
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss, Pp 102433-(2020)
NeuroImage : Clinical
NeuroImage : Clinical
Graphical abstract
Highlights • We demonstrated reliable and fast whole-brain 3D-MRSI of high-grade gliomas at 7T. • tCho, Gln, and Gly were increased in contrast-enhancing tumor tissue. • Results corresponded well to clinical data, but sh
Highlights • We demonstrated reliable and fast whole-brain 3D-MRSI of high-grade gliomas at 7T. • tCho, Gln, and Gly were increased in contrast-enhancing tumor tissue. • Results corresponded well to clinical data, but sh
Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications
Autor:
Valentina Villalobos Coa, Lissette Jiménez, Vito Lubes, Giuseppe Lubes, Carlos Ciangherotti, Edgar Del Carpio, Lino Hernández
Publikováno v:
Coordination Chemistry Reviews
Highlights • Vanadium history and industrial applications. • Recent research on metal vanadium complexes with amino acids. • Vanadium complexes with amino acids and their properties. • Vanadium complexes are promising candidates as metallopha
Autor:
Mototeru Yamane
Publikováno v:
Biochimie Open
Biochimie Open, Vol 1, Iss C, Pp 11-27 (2015)
Biochimie Open, Vol 1, Iss C, Pp 11-27 (2015)
Ceramides (Cers) have recently been identified as key signaling molecules that mediate biological functions such as cell growth, differentiation, senescence, apoptosis, and autophagy. However, the functions of Cer accumulation in necrotic cell death
Autor:
Nicholas J. Talbot, Sreedhar Kilaru, Martin Schuster, Darren M. Soanes, Congping Lin, David J. Studholme, Gero Steinberg
Publikováno v:
Fungal Genetics and Biology
Highlights • We generated a Z. tritici codon-optimized gene for green fluorescent protein (ZtGFP). • In epi-fluorescence and confocal microscopy, ZtGFP is brighter and more stable than eGFP. • We provide 3 vectors that carry AcGFP, eGFP and ZtG