Zobrazeno 1 - 10
of 3 265
pro vyhledávání: '"Septin"'
Autor:
Ting ting Cai, Christophe Desterke, Juan Peng, Jean Agnetti, Peixuan Song, Dalila Ouazib, Alexandre Dos Santos, Catherine Guettier, Didier Samuel, Ama Gassama‐Diagne
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2369-2392 (2024)
Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous and aggressive liver cancer with limited therapeutic options. Precise classification and immunotherapy are perspectives to improve the treatments. We reported the role of septin 9 in ap
Externí odkaz:
https://doaj.org/article/0d7ea371336a4bdea92b034e03517704
Autor:
Ondrej Sanovec, Michaela Frolikova, Veronika Kraus, Jana Vondrakova, Maryam Qasemi, Daniela Spevakova, Ondrej Simonik, Lindsay Moritz, Drew Lewis Caswell, Frantisek Liska, Lukas Ded, Jiri Cerny, Tomer Avidor-Reiss, Saher Sue Hammoud, Hubert Schorle, Pavla Postlerova, Klaus Steger, Katerina Komrskova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
There is a well-established link between abnormal sperm chromatin states and poor motility, however, how these two processes are interdependent is unknown. Here, we identified a possible mechanistic insight by showing that Protamine 2, a nuclear DNA
Externí odkaz:
https://doaj.org/article/01217af291054fa2bce783d7e7012b4f
Autor:
Nan Liu, Shuai Wang, Munan Li, Nan Zhao, Deyu Wang, Rui Zhang, Mingxin Yu, Luoyi Zhao, Siwei Zhang, Fangbin Han, Ying Zhao, Quan Liu
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107377- (2024)
The bromodomain and extraterminal domain (BET) family proteins serve as primary readers of acetylated lysine residues and play crucial roles in cell proliferation and differentiation. Dysregulation of BET proteins has been implicated in tumorigenesis
Externí odkaz:
https://doaj.org/article/26076223807147c29c4a08c84e842955
Autor:
John H. Henson, Gabriela Reyes, Nina T. Lo, Karina Herrera, Quenelle W. McKim, Hannah Y. Herzon, Maritriny Galvez-Ceron, Alexandra E. Hershey, Rachael S. Kim, Charles B. Shuster
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Our knowledge of the assembly and dynamics of the cytokinetic contractile ring (CR) in animal cells remains incomplete. We have previously used super-resolution light microscopy and platinum replica electron microscopy to elucidate the ultrastructura
Externí odkaz:
https://doaj.org/article/132b6501bd224f6d8424efecc7df2e6a
Akademický článek
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Publikováno v:
Journal of Fungi, Vol 10, Iss 9, p 662 (2024)
Eukaryotic cells must accurately transfer their genetic material and cellular components to their daughter cells. Initially, cells duplicate their chromosomes and subsequently segregate them toward the poles. The actomyosin ring, a crucial molecular
Externí odkaz:
https://doaj.org/article/ca4eab899dc94443ae606c3626a3f5c8
Autor:
Rita De Gasperi, Laszlo Csernoch, Beatrix Dienes, Monika Gonczi, Jayanta K Chakrabarty, Shahar Goeta, Abdurrahman Aslan, Carlos A Toro, David Karasik, Lewis M Brown, Marco Brotto, Christopher P Cardozo
Publikováno v:
eLife, Vol 12 (2024)
Here, we investigated the mechanisms by which aging-related reductions of the levels of Numb in skeletal muscle fibers contribute to loss of muscle strength and power, two critical features of sarcopenia. Numb is an adaptor protein best known for its
Externí odkaz:
https://doaj.org/article/0f068916cd8b4549bdd0767378793140
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into cytoskeletal filaments. Like actin and ⍺ and β
Externí odkaz:
https://doaj.org/article/de31782bf02b4e68b120fc152af918da
Publikováno v:
Journal of Fungi, Vol 10, Iss 2, p 115 (2024)
Cytokinesis is required to separate two daughter cells at the end of mitosis, and septins play crucial roles in many aspects of cytokinesis. While septins have been intensively studied in many model organisms, including the budding yeast Saccharomyce
Externí odkaz:
https://doaj.org/article/854804d12ef94f3fb8e7675028a0ec78
Akademický článek
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