Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Seppo J. Vainio"'
Publikováno v:
Frontiers in Urology, Vol 4 (2024)
Kidney diseases such as glomerulopathy and nephron dysfunction are estimated to grow to more than 900 million cases by 2030, in 45% of which kidney transplantation will be required, representing a major challenge for biomedicine. A wealth of progress
Externí odkaz:
https://doaj.org/article/d028a704db604d4aa9073bd2e87cacec
Autor:
Santeri Kankaanpää, Markus Nurmi, Markus Lampimäki, Heidi Leskinen, Anni Nieminen, Anatoliy Samoylenko, Seppo J. Vainio, Sari Mäkinen, Lauri Ahonen, Juha Kangasluoma, Tuukka Petäjä, Sirja Viitala
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 4, Pp n/a-n/a (2024)
Abstract Isolation of extracellular vesicles (EV) has been developing rapidly in parallel with the interest in EVs. However, commonly utilized protocols may not suit more challenging sample matrixes and could potentially yield suboptimal results. Kno
Externí odkaz:
https://doaj.org/article/8289d10935044b98bbb2a0d5f9a75d08
Autor:
Diana R. Pereira, Eunice R. Silva, Carina Carvalho-Maia, Sara Monteiro-Reis, Catarina Lourenço, Rita Calisto, Ricardo João Teixeira, Linda E. Carlson, Genevieve Bart, Seppo J. Vainio, M. Goreti F. Sales, Carmen Jerónimo, Rui Henrique
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background Mindfulness-based interventions (MBIs) have been used in oncology contexts as a promising tool with numerous benefits for various health-related and psychosocial outcomes. Despite the increasing popularity of MBIs, few randomized
Externí odkaz:
https://doaj.org/article/a87815bda19647698d0753152c4c0c8a
Autor:
Anatoliy Samoylenko, Martin Kögler, Artem Zhyvolozhnyi, Olha Makieieva, Geneviève Bart, Sampson S. Andoh, Matthieu Roussey, Seppo J. Vainio, Jussi Hiltunen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Extracellular vesicles (EVs) represent a diverse group of small membrane-encapsulated particles involved in cell–cell communication, but the technologies to characterize EVs are still limited. Hypoxia is a typical condition in solid tumors
Externí odkaz:
https://doaj.org/article/3fada35232c74dd4979f769eff191495
Autor:
Sira Karvinen, Tero Sievänen, Jari E. Karppinen, Pekka Hautasaari, Geneviève Bart, Anatoliy Samoylenko, Seppo J. Vainio, Juha P. Ahtiainen, Eija K. Laakkonen, Urho M. Kujala
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundTo date, microRNAs (miRs) carried in extracellular vesicles (EVs) in response to exercise have been studied in blood but not in non-invasively collectable body fluids. In the present study, we examined whether six exercise–responsive miRs
Externí odkaz:
https://doaj.org/article/42e9acf1821740ed8d598b420366d4c6
Autor:
Qi Xu, Sanna Junttila, Andreas Scherer, Khem Raj Giri, Oona Kivelä, Ilya Skovorodkin, Juha Röning, Susan E. Quaggin, Hans-Peter Marti, Jingdong Shan, Anatoly Samoylenko, Seppo J. Vainio
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1503-1515 (2017)
Three-dimensional (3D) organoids provide a new way to model various diseases, including cancer. We made use of recently developed kidney-organ-primordia tissue-engineering technologies to create novel renal organoids for cancer gene discovery. We the
Externí odkaz:
https://doaj.org/article/a317aeef9ba34ab0804995a62f0c4930
Autor:
Mirja Krause, Aleksandra Rak-Raszewska, Florence Naillat, Ulla Saarela, Christina Schmidt, Veli-Pekka Ronkainen, Geneviève Bart, Seppo Ylä-Herttuala, Seppo J. Vainio
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
The subfraction of extracellular vesicles, called exosomes, transfers biological molecular information not only between cells but also between tissues and organs as nanolevel signals. Owing to their unique properties such that they contain several RN
Externí odkaz:
https://doaj.org/article/f8be4f04bb7f49f087cd20a1f0e8b370
Autor:
Sara Monteiro-Reis, Carina Carvalho-Maia, Genevieve Bart, Seppo J. Vainio, Juliana Pedro, Eunice R. Silva, Goreti Sales, Rui Henrique, Carmen Jerónimo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3267 (2021)
Secreted extracellular vesicles (EVs) are heterogeneous cell-derived membranous granules which carry a large diversity of molecules and participate in intercellular communication by transferring these molecules to target cells by endocytosis. In the
Externí odkaz:
https://doaj.org/article/ffa75704f86d450082c59e512587b518
Autor:
Pavle Andjus, Maja Kosanović, Katarina Milićević, Mukesh Gautam, Seppo J. Vainio, Denis Jagečić, Elena N. Kozlova, Augustas Pivoriūnas, Juan-Carlos Chachques, Mirena Sakaj, Giulia Brunello, Dinko Mitrecic, Barbara Zavan
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6859 (2020)
Extracellular vesicles (EVs) have recently attracted a great deal of interest as they may represent a new biosignaling paradigm. According to the mode of biogenesis, size and composition, two broad categories of EVs have been described, exosomes and
Externí odkaz:
https://doaj.org/article/221ca76bdd2a4ee181c8f3801eeb4afe
Publikováno v:
Cells, Vol 9, Iss 2, p 329 (2020)
Generation of kidney organoids from pluripotent stem cells (PSCs) is regarded as a potentially powerful way to study kidney development, disease, and regeneration. Direct differentiation of PSCs towards renal lineages is well studied; however, most o
Externí odkaz:
https://doaj.org/article/0f93368927ae4e7f94a1d245df9f57ca