Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Seppo, Kaijalainen"'
Autor:
Tania Durré, Florent Morfoisse, Charlotte Erpicum, Marie Ebroin, Silvia Blacher, Melissa García-Caballero, Christophe Deroanne, Thomas Louis, Cédric Balsat, Maureen Van de Velde, Seppo Kaijalainen, Frédéric Kridelka, Lars Engelholm, Ingrid Struman, Kari Alitalo, Niels Behrendt, Jenny Paupert, Agnès Noel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
VEGF-C drives lymphangiogenesis through binding to its receptors VEGFR-2 and VEGFR-3. Here, Durré et al. identify uPARAP/Endo180 as a critical regulator of VEGFR-2/VEGFR-3 heterodimerisation and downstream signaling in response to VEGF-C, and show t
Externí odkaz:
https://doaj.org/article/38a29c790f274d7296f82886c67f9d1c
Autor:
Joseph M. Ziegelbauer, Caj Haglund, Veijo Nurminen, Mathias Francois, Riikka E. Kallinen, Thomas Günther, Raquel Diaz, Päivi M. Ojala, Endrit Elbasani, Adam Grundhoff, Teijo Pellinen, Silvia Gramolelli, Krista Tuohinto, Mark Bower, Seppo Kaijalainen
Publikováno v:
Cancer Res
Kaposi sarcoma is a tumor caused by Kaposi sarcoma herpesvirus (KSHV) infection and is thought to originate from lymphatic endothelial cells (LEC). While KSHV establishes latency in virtually all susceptible cell types, LECs support spontaneous expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cd3534c76a2d0ded2d322c7f857448
https://doi.org/10.1158/0008-5472.can-19-3103
https://doi.org/10.1158/0008-5472.can-19-3103
Autor:
Päivi M. Ojala, Thomas Günther, Krista Tuohinto, Adam Grundhoff, Silvia Gramolelli, Endrit Elbasani, Mark Bower, Caj Haglund, Mathias Francois, Raquel Diaz, Veijo Nurminen, Joseph M. Ziegelbauer, Riikka E. Kallinen, Seppo Kaijalainen
Kaposi sarcoma (KS) is a tumour of endothelial origin caused by KS herpesvirus (KSHV) infection and suggested to originate from lymphatic endothelial cells (LECs). While KSHV establishes latency in virtually all susceptible cell types, LECs support a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2036911cf5d461226a21ff2d0ec7de48
Autor:
Marianne, Lähde, Sarika, Heino, Jenny, Högström, Seppo, Kaijalainen, Andrey, Anisimov, Dustin, Flanagan, Pauliina, Kallio, Veli-Matti, Leppänen, Ari, Ristimäki, Olli, Ritvos, Katherine, Wu, Tuomas, Tammela, Michael, Hodder, Owen J, Sansom, Kari, Alitalo
Publikováno v:
Gastroenterology. 160(1)
Mutations in the APC gene and other genes in the Wnt signaling pathway contribute to development of colorectal carcinomas. R-spondins (RSPOs) are secreted proteins that amplify Wnt signaling in intestinal stem cells. Alterations in RSPO genes have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::371e6f7f66460c761daff918593b3f25
https://pubmed.ncbi.nlm.nih.gov/32941878
https://pubmed.ncbi.nlm.nih.gov/32941878
Autor:
Marianne Lähde, Sarika Heino, Jenny Högström, Veli-Matti Leppänen, Seppo Kaijalainen, Olli Ritvos, Owen Sansom, Kari Alitalo
Publikováno v:
Cancer Research. 79:LB-094
Colorectal cancers (CRCs) most commonly develop from adenomas harboring a mutant APC gene that leads to aberrant activation of the canonical Wnt/ß-catenin pathway. One of the mechanisms of adenoma progression involves the PROX1 transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909fc35d725e559df3ce96c3d3dba6ab
https://doi.org/10.1158/1538-7445.am2019-lb-094
https://doi.org/10.1158/1538-7445.am2019-lb-094
Autor:
Andrey Anisimov, Tanja Holopainen, Seppo Kaijalainen, Tuomas Tammela, Seppo Ylä-Herttuala, Masahiro Yamamoto, Terhi Karpanen, Kari Alitalo, Kaisa Lehti, Wei Zheng
Publikováno v:
Blood; Vol 118
Notch signaling plays a central role in cell-fate determination, and its role in lateral inhibition in angiogenic sprouting is well established. However, the role of Notch signaling in lymphangiogenesis, the growth of lymphatic vessels, is poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55495e9b7089d0c50aea8adf79e55578
https://doi.org/10.1182/blood-2010-11-317800
https://doi.org/10.1182/blood-2010-11-317800
Autor:
Timo Otonkoski, Sarika Heino, Pauliina Kallio, Marianne Lähde, Zoltán Wiener, Seppo Kaijalainen, Diego Balboa, Veli-Matti Leppänen, Sylvie Robine, Kari Alitalo, Jenny Högström
Publikováno v:
Cancer Research. 78:1143-1143
Colorectal cancer (CRC) is one of the leading causes of cancer-related morbidity and mortality. Signaling pathways, such as the Wnt and Notch pathways, are essential for the maintenance and differentiation of wild-type intestinal stem cells. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a5eab3c7abb7ea7718037a37ef74355
https://doi.org/10.1158/1538-7445.am2018-1143
https://doi.org/10.1158/1538-7445.am2018-1143
Autor:
Michael Jeltsch, Seppo Kaijalainen, Kari Alitalo, Jarkko Soronen, Petra Korpisalo, Andrey Anisimov, Seppo Ylä-Herttuala, Annamari Alitalo, Veli-Matti Leppänen
Publikováno v:
Circulation Research. 104:1302-1312
The therapeutic potential of vascular endothelial growth factor (VEGF)-C and VEGF-D in skeletal muscle has been of considerable interest as these factors have both angiogenic and lymphangiogenic activities. Previous studies have mainly used adenovira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669f77a84b9a7b7525ebc9b16928966a
https://doi.org/10.1161/circresaha.109.197830
https://doi.org/10.1161/circresaha.109.197830
Autor:
Kari Juntunen, Viktor Kuvshinov, Andrey Anisimov, Seppo Kaijalainen, Anne Kanerva, Kimmo Koivu
Publikováno v:
Molecular Breeding. 19:241-253
The aim of our study was to identify the highest expressing rubisco small subunit (RbcS) promoters (pRbcS) from the cotyledons of germinating seedlings of Brassica rapa var. oleifera to drive high-level and preferably stage-specific transgenic protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f20e9e2dbbdb8a5efffc03a68d0a9e
https://doi.org/10.1007/s11032-006-9059-5
https://doi.org/10.1007/s11032-006-9059-5
Autor:
Kristina Lindström, Dengyu Li, Xiaoping Zhang, Zewdu Terefework, Qiang Chen, Seppo Kaijalainen
Publikováno v:
Plant and Soil. 255:605-617
A high degree of genetic diversity among 125 peanut bradyrhizobial strains and among 32 peanut cultivars collected from different regions of China was revealed by using the amplified fragment length polymorphism (AFLP) technique. Eighteen different p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b136cd21cd13cc2426b8a435620c299
https://doi.org/10.1023/a:1026039503225
https://doi.org/10.1023/a:1026039503225