Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sepehr Abdolahi"'
Publikováno v:
Journal of Kerman University of Medical Sciences, Vol 28, Iss 6, Pp 626-636 (2021)
Background: Several types of cancer have mutations in the tumor suppressor gene p53. Environmental mutagens such as heavy metals play an undeniable role in p53 mutations and leave the mutational fingerprint on the TP53 gene. Therefore, the study of p
Externí odkaz:
https://doaj.org/article/9b972236111e46fc92f6ed9133fb2c9d
Autor:
Nasser Pouladi, Sepehr Abdolahi
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Background Novel coronavirus (SARS‐CoV‐2) became an epidemic disease and lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms related to coronavirus disease‐19 (COVID‐19) were different ranging from mild
Externí odkaz:
https://doaj.org/article/6aaaf75beed64d10afad76007f74809a
Autor:
Sepehr Abdolahi, Nasser Pouladi
Publikováno v:
Journal of Kerman University of Medical Sciences, Vol 26, Iss 4, Pp 271-279 (2019)
Background: Non-coding RNAs apply regulations on expression or function of a gene. A class of non-coding RNAs, natural antisense transcripts, might overlap with their flanking genes and emerge a new complexity upon regulation. WRAP53, is a natural an
Externí odkaz:
https://doaj.org/article/19e953b61b55460298c33afebe2bdc2f
Haplotype and linkage disequilibrium of TP53-WRAP53 locus in Iranian-Azeri women with breast cancer.
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220727 (2019)
Among the cancer susceptibility genes, TP53 is one of the crucial genes involved in cell cycle regulations and, therefore, it greatly affects breast cancer initiation and progression. In addition, WRAP53-a natural antisense transcript-regulates TP53
Externí odkaz:
https://doaj.org/article/e0301d41c7b14f94875005f41392794f
Autor:
Sepehr Abdolahi, Mahsa Pourmahdi, Reza Safaralizadeh, Ali M. Rajabi, Pirooz Ebrahimi, Ali Saber
Publikováno v:
Current stem cell research & therapy. 16(7):877-887
Background: Cancer stem cells (CSCs) are a small subpopulation of cells within tumors and play significant roles in tumorigenesis, metastasis, resistance to treatment, and relapse. They are defined by self-renewal and multi-lineage differentiation, a
Autor:
Mehran Khodaei, Molood Akbarzadeh, Mahsa Pourmahdi, Sepehr Abdolahi, Amir Khodavirdipour, Reza Safaralizadeh, Reyhaneh Ravanbakhsh, Ali Emami, Ali Saber, Ali M. Rajabi, Mohammad Ali Hosseinpourfeizi
Publikováno v:
Recent patents on anti-Cancer drug discovery, 15(4), 329-340. BENTHAM SCIENCE PUBL LTD
Background:The Notch signaling pathway has a key role in angiogenesis and Delta-Like Ligand 4 (DLL4) is one of the main ligands of Notch involved in cell proliferation in sprouting vessels.Objective:In this study, we aimed to evaluate the expression
Publikováno v:
Human Heredity. 85:51-60
Introduction: Breast cancer is a heterogeneous and multifactorial disease. TP53 and PAI-1 as important tumor suppressor genes are involved in the development, invasion, and metastasis of many cancers. This study’s objective was to demonstrate the c
Autor:
Reza Safaralizadeh, Sepehr Abdolahi, Sepideh Bastani, Samaneh Tayefeh-Gholami, Melika Maydanchi, Ali Saber, Ali M. Rajabi
Publikováno v:
Journal of gastrointestinal cancer. 53(3)
Gastric cancer (GC) is one of the most frequent tumors worldwide and identification of a sensitive and specific prognostic biomarker is of great importance. Long non-coding RNAs (lncRNAs) play crucial roles in tumorigenesis of various malignancies. I
Publikováno v:
Meta Gene. 19:117-122
p53 plays an important role in genome integrity and controls cell proliferation, induces cell cycle arrest, apoptosis, and DNA repair. Various lncRNAs, proteins, and small molecules can influence its activity. WRAP53, which lies in the opposite direc
Autor:
Mona Bakhshi, Ali Saber, Fereshteh Baniardalan, Melika Maydanchi, Aref Sobhkhizy, Sepehr Abdolahi, Ali M. Rajabi, Reza Safaralizadeh
Publikováno v:
The FASEB Journal. 35