Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Seow Theng, Ong"'
Autor:
Sanling Liu, Yue Zhao, Hao Dong, Liang Xiao, Yong Zhang, Yuqin Yang, Seow Theng Ong, K. George Chandy, Longhua Zhang, Changlin Tian
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-5 (2021)
Externí odkaz:
https://doaj.org/article/9d96dfeff9da404090d7dd2ec77fc865
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Voltage-gated potassium (Kv) channels modulate the function of electrically-excitable and non-excitable cells by using several types of “gates” to regulate ion flow through the channels. An important gating mechanism, C-type inactivation, limits
Externí odkaz:
https://doaj.org/article/827421028ee94b0188d27e06ffec8e9d
Autor:
Julian L. Goggi, Shivashankar Khanapur, Boominathan Ramasamy, Siddesh V. Hartimath, Tang Jun Rong, Peter Cheng, Yun Xuan Tan, Xin Yi Yeo, Sangyong Jung, Stephanie Shee Min Goay, Seow Theng Ong, You Yi Hwang, K. George Chandy, Edward G. Robins
Publikováno v:
Cancers, Vol 14, Iss 5, p 1217 (2022)
Immune checkpoint inhibitors have shown great promise, emerging as a new pillar of treatment for cancer; however, only a relatively small proportion of recipients show a durable response to treatment. Strategies that reliably differentiate durably-re
Externí odkaz:
https://doaj.org/article/10427aba14f846449f2582059c328cbe
Autor:
Ricardo C. H. del Rosario, Jeremie Poschmann, Carey Lim, Catherine Y. Cheng, Pavanish Kumar, Catherine Riou, Seow Theng Ong, Sherif Gerges, Hajira Shreen Hajan, Dilip Kumar, Mardiana Marzuki, Xiaohua Lu, Andrea Lee, Giovani Claresta Wijaya, Nirmala Arul Rayan, Zhong Zhuang, Elsa Du Bruyn, Cynthia Bin Eng Chee, Bernett Lee, Josephine Lum, Francesca Zolezzi, Michael Poidinger, Olaf Rotzschke, Chiea Chuen Khor, Robert J. Wilkinson, Yee T. Wang, George K Chandy, Gennaro De Libero, Amit Singhal, Shyam Prabhakar
Publikováno v:
Nature Microbiology. 7:312-326
Host cell chromatin changes are thought to play an important role in the pathogenesis of infectious diseases. Here we describe a histone acetylome-wide association study (HAWAS) of an infectious disease, on the basis of genome-wide H3K27 acetylation
Autor:
Seow Theng Ong, Madhavi Latha Somaraju Chalasani, M. H. U. Turabe Fazil, Praseetha Prasannan, Atish Kizhakeyil, Graham D. Wright, Dermot Kelleher, Navin Kumar Verma
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Centrosome- and Golgi-localized protein kinase N-associated protein (CG-NAP), also known as AKAP450, is a cytosolic scaffolding protein involved in the targeted positioning of multiple signaling molecules, which are critical for cellular functioning.
Externí odkaz:
https://doaj.org/article/a2b7a23df7874ee593b793b73190f393
Autor:
Hariharan Ezhilarasu, Seow Theng Ong, Chak Ming Leung, Praseetha Prasannan, Mohammed Kamruddin, Venkatesh Mayandi, Kantha Deivi Arunachalam, Nandhini Sunderasan, Sathish Kumar Karuppannan, Seeram Ramakrishna, Veluchamy A Barathi, Rajamani Lakshminarayanan, Ilango Kaliappan, Raghavendra Ramalingam, Chetna Dhand, Navin Kumar Verma
Publikováno v:
ACS Applied Materials & Interfaces. 13:24356-24369
Burn wounds are susceptible to microbial invasion from both resident and exogenous bacteria, which becomes a critical public health issue and causes substantial economic burden. There is a perceived demand to produce new antimicrobial wound dressings
Autor:
Raghavendra Ramalingam, Chetna Dhand, Chak Ming Leung, Hariharan Ezhilarasu, Praseetha Prasannan, Seow Theng Ong, Sundarapandian Subramanian, Mohammed Kamruddin, Rajamani Lakshminarayanan, Seeram Ramakrishna, Navin Kumar Verma, Kantha Deivi Arunachalam
Publikováno v:
Nanomaterials, Vol 9, Iss 3, p 462 (2019)
Electrospun fibers have emerged as promising materials in the field of biomedicine, due to their superior physical and cell supportive properties. In particular, electrospun mats are being developed for advanced wound dressing applications. Such appl
Externí odkaz:
https://doaj.org/article/0f0ad72375bf49fba681ee2b9cf8f823
Autor:
Navin K. Verma, Brandon Han Siang Wong, Seow Theng Ong, Stephanie Shee Min Goay, Ying Swan Ho, Shuwen Chen, Xuezhi Bi, Heesung Shim, Heike Wulff, Richard D. Webster, Vishalkumar G. Shelat, K. George Chandy
Publikováno v:
Biophysical Journal. 122:256a
Publikováno v:
Natural Product Reports. 37:703-716
Covering: Up to 2020Ion channels are a vast super-family of membrane proteins that play critical physiological roles in excitable and non-excitable cells. Their biomedical importance makes them valuable and attractive drug targets for neurological, c
Autor:
Anu Tyagi, Tofayel Ahmed, Shi Jian, Saumya Bajaj, Seow Theng Ong, Stephanie Shee Min Goay, Yue Zhao, Igor Vorobyov, Changlin Tian, K. George Chandy, Shashi Bhushan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 5
We report two structures of the human voltage-gated potassium channel (Kv) Kv1.3 in immune cells alone (apo-Kv1.3) and bound to an immunomodulatory drug called dalazatide (dalazatide-Kv1.3). Both the apo-Kv1.3 and dalazatide-Kv1.3 structures are in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58505ad3a36582e334a9cff6fe8632f1
https://hdl.handle.net/10356/162571
https://hdl.handle.net/10356/162571