Výsledky vyhledávání - "Seow Fong Yap"

Normal Sequence and Activity but Reduced Levels of DNA-Pkcs in Human Lymphoblastic Cells Implicate Impaired Protein Stability with Radiosensitive Phenotype

Autor: Seow Fong Yap, Rajamanickam Baskar, Cynthia Sk Boo, Susan Le Loong

Publikováno v: Journal of Cancer

Background: Non-homologous end joining (NHEJ) is the main repair pathway for DNA double strand breaks (DSBs) induced by ionizing radiation in mammalian cells. Subsets of cancer patients are hypersensitive to radiotherapy after standard doses. We soug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd71d1601886206da0ebf8fd60dabf38
https://doi.org/10.7150/jca.6453

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Fanconi's anemia in adulthood: chemoradiation-induced bone marrow failure and a novel FANCA mutation identified by targeted deep sequencing

Autor: Steve Rozen, Jabed Iqbal, Bin Tean Teh, William Hwang, Seow Fong Yap, Wan-Teck Lim, Patrick Tan, Iain Beehuat Tan, Zhi Jiang Zang, Ioana Cutcutache, Eng Huat Tan

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 29(20)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f968c6224e5e0c0670f651727d98f5a6
https://pubmed.ncbi.nlm.nih.gov/21519011

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The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation

Autor: Weining Chen, Seow Fong Yap, Shan Chen, Louis Lim

Publikováno v: The Journal of biological chemistry. 271(42)

The p21-activated kinase (PAK) is a downstream target of Rac and CDC42, members of the Ras-related Rho subfamily, that mediates signaling pathway leading to cytoskeletal reorganization. To investigate its function in Caenorhabditis elegans developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc987076aaa49b189e113e7ef67c99b
https://pubmed.ncbi.nlm.nih.gov/8824291

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A Drosophila gene encoding a protein with similarity to diacylglycerol kinase is expressed in specific neurons

Autor: Seow Fong Yap, Louis Lim, Mary-Ann Chiam, Nicholas Harden

A Drosophila gene encoding a protein with similarity to diacylglycerol kinase (DGK) was isolated by screening a genomic DNA library with a human DGK cDNA under low-stringency hybridization conditions. This putative Drosophila DGK gene (dDGK) maps to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c94d48e299ac59f07d399b978e2212
https://europepmc.org/articles/PMC1132187/

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Akademický článek

The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway.

Autor: Ward, Yvona, Seow-Fong Yap, Ravichandran, V., Matsumura, Fumio, Ito, Masaaki, Spinelli, Beth, Kelly, Kathleen

Publikováno v: Journal of Cell Biology. 4/15/2002, Vol. 157 Issue 2, p291. 12p. 3 Color Photographs, 6 Diagrams, 2 Charts, 7 Graphs.

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