Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Seoung Ae Lee"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Previously, a telomerase-derived 16-mer peptide, GV1001, developed as an anticancer vaccine, was reported to exert antiviral effects on human immunodeficiency virus or hepatitis C virus in a heat shock protein-dependent manner. Here we investigated w
Externí odkaz:
https://doaj.org/article/e01446fee2ed45c09afaf49f59c265bd
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract To investigate the potential role of vitamin D (1,25(OH)2D3) in preventing the development of nasal polyps, we examined the effect of vitamin D on myofibroblast differentiation and extracellular matrix (ECM) production in TGF-β1-induced nas
Externí odkaz:
https://doaj.org/article/11559d6f25224c8a808047db444ec411
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP. Glucocorticoids are a type of
Externí odkaz:
https://doaj.org/article/fa34d5da0d1e4e9faa599e4f6c51b888
Publikováno v:
Viruses, Vol 13, Iss 3, p 433 (2021)
Pyruvate kinase M2 (PKM2) mainly catalyzes glycolysis, but it also exerts non-glycolytic functions in several cancers. While it has been shown to interact with the human papillomavirus 16 (HPV16) E7 oncoprotein, the functional significance of PKM2 in
Externí odkaz:
https://doaj.org/article/ffe2209b0cf2484a813ea31387b934e7
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Epithelial-mesenchymal transition (EMT) is a biological process that allows epithelial cells to assume a mesenchymal cell phenotype. EMT is considered as a therapeutic target for several persistent inflammatory airway diseases related to tissue remod
Externí odkaz:
https://doaj.org/article/37a8fbefac8d4d14b636a0063ac4f2ea
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157058 (2016)
BACKGROUND:Diesel exhaust particles (DEP) are a major source of air pollution. Nasal fibroblasts are known to produce various cytokines and chemokines. The aim of this study was to evaluate DEP-induced cytokines and chemokines in nasal fibroblasts an
Externí odkaz:
https://doaj.org/article/93f909bbbdba42dd97b169ed0e2d1c49
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168195 (2016)
Baicalin, a Chinese herbal medicine, has anti-fibrotic and anti-inflammatory effects. The aims of present study were to investigate the effects of baicalin on the myofibroblast differentiation, extracellular matrix production, migration, and collagen
Externí odkaz:
https://doaj.org/article/5f8c3bc862024409a4d106d8bca71602
Publikováno v:
Essays Biochem
There has been little progress for several decades in modalities to treat cervical cancer. While the cervix is a hormone-sensitive tissue, physiologic roles of estrogen receptor α (ERα), progesterone receptor (PR), and their ligands in this tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d5d8680312088372563fd545e9f20b
https://europepmc.org/articles/PMC8935983/
https://europepmc.org/articles/PMC8935983/
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139551 (2015)
Universal infantile hepatitis B virus (HBV) vaccination may lead to an increase in vaccine escape variants, which may pose a threat to the long-term success of massive vaccination. To determine the prevalence of occult infections in Korean vaccinated
Externí odkaz:
https://doaj.org/article/ff46e5e9f65d43d08af5eb6d48c2b2ac
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87773 (2014)
The nonstructural 5B (NS5B) protein of the hepatitis C virus (HCV) with RNA-dependent RNA polymerase (RdRp) activity plays a pivotal role in viral replication. Therefore, monitoring of its naturally occurring mutations is very important for the devel
Externí odkaz:
https://doaj.org/article/7fef2728bf564c0f821bc13d096956ca