Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Seongyeon Jo"'
Autor:
Se-Young Jo, Jeong Dong Lee, Jeongsoo Won, Jiho Park, Taeyong Kweon, Seongyeon Jo, Joohyuk Sohn, Seung-Il Kim, Sangwoo Kim, Hyung Seok Park
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110469- (2024)
Summary: This study investigates the molecular characteristics and therapeutic implications of the BRCA1 L1780P mutation, a rare variant prevalent among Korean hereditary breast cancer patients. Using patient-derived xenograft (PDX) models and cell l
Externí odkaz:
https://doaj.org/article/a7d202b4e24a4751966166cfef8184bf
Autor:
Won-Ji Ryu, Shinyoung Park, Jeong Dong Lee, Yumi Hwang, Seongyeon Jo, Kweon Tae Yong, Ja Seung Koo, Min Hwan Kim, Joo Hyuk Sohn, Hyung Seok Park
Publikováno v:
Cancer Research. 83:178-178
A patient-derived organoid (PDO) is an in vitro three-dimensional model which shows similar features in phenotypic and genetic aspects with primary tissue from patients. PDOs are useful for preclinical studies including drug sensitivity tests of tumo
Autor:
Mikyung Shin, Seongyeon Jo, Haeshin Lee, Moon Sue Lee, Dong Yun Lee, Kyuri Kim, Ji Hyun Ryu, Min Jun Kim
Publikováno v:
ACS biomaterials scienceengineering. 4(7)
All animal experiments for evaluating drug efficacy or developing medical devices are unavoidably accompanied by bleeding that result in unreliable outcomes with large variations between individuals. Herein, we developed hemostatic swabs prepared by
Autor:
Ji Hyun Ryu, Ji Suk Choi, Seong Keun Kwon, Min Rye Eom, Haeshin Lee, Moon Sue Lee, Eunsook Park, Seongyeon Jo
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 317
Oral mucosal drug delivery systems have been developed to expedite the regeneration of oral mucosa, there are still many challenges related to residence time for drugs because the ceaseless changes of saliva, mouth movement, and involuntary swallowin
Autor:
Seok Song Oh, Eui-Cheol Shin, Seon-Hui Hong, Sun-Woong Kang, Byung-Chang Oh, Ki-Suk Kim, Haeshin Lee, Moon Sue Lee, Keumyeon Kim, Mikyung Shin, Sung-Gurl Park, Seongyeon Jo
Publikováno v:
Nature Materials. 16:147-152
Bleeding is largely unavoidable following syringe needle puncture of biological tissues and, while inconvenient, this typically causes little or no harm in healthy individuals. However, there are certain circumstances where syringe injections can hav
Publikováno v:
Biomaterials. 39:173-181
A new design concept in controlled release chemistry is reported in this study. Unlike current depots that release drugs in all direction by an isotropic way, we demonstrate that directional release only to a clinically beneficial direction results i
Publikováno v:
Advanced Functional Materials. 24:7709-7716
In nature, a variety of functional water-insoluble organic materials are biologically synthesized in aqueous conditions without chemical additives and organic solvents. Insect cuticle, crustacean shells, and many others are representative examples. T
Publikováno v:
Macromolecular Research. 20:968-976
Novel in situ chondroitin sulfate (CS) hydrogel was synthesized via phosphine-mediated Michael type addition reaction by mixing precursor solutions of both CS-acrylate and CS-tri(2-carboxyethyl)phosphine (TCEP) as an electrophile and a nucleophile, r
Evaluations of nerve cell compatibility of self cross-linking chitosan-poly(ethylene oxide) hydrogel
Publikováno v:
Tissue Engineering and Regenerative Medicine. 9:84-91
Chitosan-poly(ethylene oxide) (chitosan-PEO) hydrogel was evaluated by the assays of live & dead, cell counting kit-8 (CCK-8), thiazoyl blue tetrazolium bromide (MTT) and neutral red for its applications in induction of adhesion, proliferation and di
Publikováno v:
Macromolecular Research. 19:1303-1309
The biological properties of self cross-linked chondroitin sulfate (CS)-poly(ethylene oxide) (PEO) hydrogel including degradation, in vitro bone cell behaviors, and cellular compatibility were evaluated after the induction of its gel formation throug