Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson’s Disease

Autor: Seulah Lee, Yeon Ji Suh, Yujeong Lee, Seonguk Yang, Dong Geun Hong, Dinakaran Thirumalai, Seung-Cheol Chang, Ki Wung Chung, Young-Suk Jung, Hyung Ryong Moon, Hae Young Chung, Jaewon Lee

Publikováno v: Antioxidants, Vol 10, Iss 11, p 1855 (2021)

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, and is caused by the death of dopamine neurons and neuroinflammation in the striatum and substantia nigra. Furthermore, the inflammatory response in PD is closely relat

Externí odkaz: https://doaj.org/article/24f95c4684064d02b96f11579314de8f

Di-n-butyl phthalate disrupts neuron maturation in primary rat embryo neurons and male C57BL/6 mice

Autor: Seonguk Yang, Hyung Sik Kim, Yeon Ji Suh, Jaewon Lee, Won-Jong Lee, Seung-Cheol Chang, Seulah Lee, Dong Geun Hong

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 85:56-70

Di-n-butyl phthalate (DBP) is commonly used as a plasticizer and its usage continues to increase in conjunction with plastic consumption. DBP is readily released into air, drinking water, and soil, and unfortunately, is a potent endocrine disrupter t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a74ef17c0e821d1defe776a92830dba
https://doi.org/10.1080/15287394.2021.1973631

Anti-Inflammatory Effect of IKK-Activated GSK-3β Inhibitory Peptide Prevented Nigrostriatal Neurodegeneration in the Rodent Model of Parkinson’s Disease

Autor: Seulah Lee, Dong Geun Hong, Seonguk Yang, Jaehoon Kim, Minwoo Baek, Seoyeong Kim, Dinakaran Thirumalai, Hae Young Chung, Seung-Cheol Chang, Jaewon Lee

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 998, p 998 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 998

Parkinson’s disease (PD) is a progressive movement disorder caused by nigrostriatal neurodegeneration. Since chronically activated neuroinflammation accelerates neurodegeneration in PD, we considered that modulating chronic neuroinflammatory respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09adead78c3b08382ac76c5d2b76d9e
https://www.mdpi.com/1422-0067/23/2/998

Di

Autor: Seulah, Lee, Wonjong, Lee, Seonguk, Yang, Yeon Ji, Suh, Dong Geun, Hong, Seung-Cheol, Chang, Hyung Sik, Kim, Jaewon, Lee

Publikováno v: Journal of toxicology and environmental health. Part A. 85(2)

Di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6210d53d79bda9471cd66f7e60b2974c
https://pubmed.ncbi.nlm.nih.gov/34488563

Tetrabromobisphenol A-Induced Apoptosis in Neural Stem Cells Through Oxidative Stress and Mitochondrial Dysfunction

Autor: Yujeong Lee, Hyeyoung Jeon, Seonguk Yang, Ah Hyun Kim, Won-Jong Lee, Jung-Hyun Cho, Seulah Lee, Jaewon Lee, Jeanho Yun, Young-Suk Jung

Publikováno v: Neurotoxicity research. 38(1)

Tetrabromobisphenol A (TBBPA) is widely used in materials like plastics and textiles as a fire retardant. In a previous study, we reported TBBPA might disrupt hippocampal neurogenesis and neurocognitive function in mice. However, the mechanism respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de819190f6c834d2c90757cbee6848ea
https://pubmed.ncbi.nlm.nih.gov/32108298