Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Seongsik Yun"'
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 3, Pp 473-484 (2020)
Circadian rhythms: Maternal stress can disrupt adult offspring’s biological clock When pregnant mothers are stressed, the fetus’s circadian rhythms are reprogrammed, increasing the risk of health complications later in life. Stress during pregnan
Externí odkaz:
https://doaj.org/article/f744ad0b8c104b849311da5a1810008a
Autor:
Yoo-Na Lee, Arfaxad Reyes-Alcaraz, Seongsik Yun, Cheol Soon Lee, Jong-Ik Hwang, Jae Young Seong
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230872 (2020)
Galanin receptors (GALRs) belong to the superfamily of G-protein coupled receptors. The three GALR subtypes (GALR1, GALR2, and GALR3) are activated by their endogenous ligands: spexin (SPX) and galanin (GAL). The synthetic SPX-based GALR2-specific ag
Externí odkaz:
https://doaj.org/article/d4b933417a2d421abb6124327be14c8e
Autor:
Seongsik Yun, Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Hyo Jeong Yong, Jeewon Choi, Byung-Joo Ham, Jong-Woo Sohn, Dong-Hoon Kim, Gi Hoon Son, Hyun Kim, Soon-Gu Kwon, Dong Sik Kim, Bong Chul Kim, Jong-Ik Hwang, Jae Young Seong
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Despite the established comorbidity between mood disorders and abnormal eating behaviors, the underlying molecular mechanism and therapeutics remain to be resolved. Here, we show that a spexin-based galanin receptor type 2 agonist (SG2A) simultaneous
Externí odkaz:
https://doaj.org/article/3bd03b366ad241c68e3ed73f1eea03d4
Autor:
Fatemeh Ameri Sefideh, Mi Jin Moon, Seongsik Yun, Sung In Hong, Jong-Ik Hwang, Jae Young Seong
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87901 (2014)
Gonadotropin-releasing hormone (GnRH) and the GnRH receptor (GnRHR) play an important role in vertebrate reproduction. Although many GnRHR genes have been identified in a large variety of vertebrate species, the evolutionary history of GnRHR in verte
Externí odkaz:
https://doaj.org/article/535eabaa04d0471cac635db6800a4558
Autor:
Nicolette A. Moya, Seongsik Yun, Stefan W. Fleps, Madison M. Martin, Jacob A. Nadel, Lisa R. Beutler, Larry S. Zweifel, Jones G. Parker
Publikováno v:
Neuropsychopharmacology. 48:690-699
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6da24a9f43bf426e246376f0ff1cb018
https://doi.org/10.1038/s41386-022-01492-1
https://doi.org/10.1038/s41386-022-01492-1
Autor:
Nicolette A. Moya, Seongsik Yun, Stefan W. Fleps, Madison M. Martin, Jacob A. Nadel, Lisa R. Beutler, Larry S. Zweifel, Jones G. Parker
BACKGROUNDExcess dopamine release in the dorsal striatum (DS) is linked to psychosis. Antipsychotics are thought to work for positive symptoms by blocking striatal D2 dopamine receptors, but they lack efficacy for the negative and cognitive symptoms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7224db7b454f6de9729c0e998845c48b
https://doi.org/10.1101/2022.08.09.503421
https://doi.org/10.1101/2022.08.09.503421
Autor:
Nai-Hsing Yeh, Madison M Martin, Seongsik Yun, Jones Griffith Parker, Ben Yang, Anis Contractor
Overactive dopamine transmission in psychosis is predicted to unbalance striatal output via D1- and D2-dopamine receptor-expressing spiny-projection neurons (SPNs). Antipsychotic drugs are thought to re-balance this output by blocking D2-receptor sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd945bb0c13a9df995edb2582854bdbd
https://doi.org/10.1101/2021.08.03.454992
https://doi.org/10.1101/2021.08.03.454992
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Neurodevelopment and mature brain function are spatiotemporally regulated by various cytokines and chemokines. The chemokine-like neuropeptide FAM19A1 is a member of family with sequence similarity 19 (FAM19), which is predominantly expressed in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac676ba74e04c621546b547af0d77c9
http://europepmc.org/articles/PMC7052240
http://europepmc.org/articles/PMC7052240
Autor:
Arfaxad Reyes-Alcaraz, Jae Young Seong, Cheol Soon Lee, Jong Ik Hwang, Yoo Na Lee, Seongsik Yun
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230872 (2020)
PLoS ONE
PLoS ONE
Galanin receptors (GALRs) belong to the superfamily of G-protein coupled receptors. The three GALR subtypes (GALR1, GALR2, and GALR3) are activated by their endogenous ligands: spexin (SPX) and galanin (GAL). The synthetic SPX-based GALR2-specific ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c840bd9373a2cfa894fc4f0f06616dd
https://doaj.org/article/d4b933417a2d421abb6124327be14c8e
https://doaj.org/article/d4b933417a2d421abb6124327be14c8e
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 52, Iss 3, Pp 473-484 (2020)
Experimental and Molecular Medicine, Vol 52, Iss 3, Pp 473-484 (2020)
Maternal stress has long-lasting influences on the brain functions of offspring, and several brain regions have been proposed to mediate such programming. Although perinatal programming of crosstalk between the circadian and stress systems has been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed061a861c5e9c764854c499ef7b12e2
https://pubmed.ncbi.nlm.nih.gov/32161397
https://pubmed.ncbi.nlm.nih.gov/32161397