Decursin induces apoptosis in glioblastoma cells, but not in glial cells via a mitochondria-related caspase pathway.

Autor: Seung Tack Oh¹, Seongmi Lee², Cai Hua³, Byung-Soo Koo⁴, Sok Cheon Pak⁵, Dong-Il-Kim⁶ obgykdi@hanmail.net, Songhee Jeon³ jsong0304@jnu.ac.kr, Boo Ahn Shin⁷ bashin@jnu.ac.kr

Publikováno v: Korean Journal of Physiology & Pharmacology. Jan2019, Vol. 23 Issue 1, p29-35. 7p.

Nasal Cavity Administration of Melanin-Concentrating Hormone Improves Memory Impairment in Memory-Impaired and Alzheimer’s Disease Mouse Models

Autor: Seung Tack Oh, Jongpil Kim, Ha Jin Jeong, Hi-Joon Park, Jihoon Jo, Songhee Jeon, Sok Cheon Pak, Manikandan Samidurai, Seongmi Lee, Quan Feng Liu

Publikováno v: Molecular Neurobiology. 56:8076-8086

Melanin-concentrating hormone (MCH) is a highly conserved neuropeptide known to exhibit important functions in the brain. Some studies have reported that MCH improves memory by promoting memory retention. However, the precise molecular mechanisms by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b3eb82bf4746804edb224e506500c6
https://doi.org/10.1007/s12035-019-01662-1

MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation

Autor: Ha Jin Jeong, Sok Cheon Pak, Jongpil Kim, Hi-Joon Park, Hyun Seok Cho, Seung Tack Oh, Songhee Jeon, Seongmi Lee

Publikováno v: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology

Familial Parkinson's disease (PD) has been linked to point mutations and duplication of the α-synuclein (α-syn) gene. Mutant α-syn expression increases the vulnerability of neurons to exogenous insults. In this study, we developed a new PD model i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3f6a3fe88282fafa6cc840e090f74e
http://europepmc.org/articles/PMC5709479

Chloride channel-4 knockout mice show delayed neuronal differentiation and neurodevelopment

Autor: Sohee Jung, Seongmi Lee, Bom-Lee Lee, Songhee Jeon, Yeni Kim, Jinju Han, Hajin Jeong

Publikováno v: IBRO Reports. 6:S338

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edbc70f9b20327a39a8ee77a43cf2bd4
https://doi.org/10.1016/j.ibror.2019.07.1044

Erythro-austrobailignan-6 down-regulates HER2/EGFR/integrinβ3 expression via p38 activation in breast cancer

Autor: Heung-Mook Shin, Seung Tack Oh, Dong-Il Kim, Seongmi Lee, Yura Choi, Ha Jin Jeong, Jae-Hyun Han, Yun Ju Kwon, Hanna Lee, Songhee Jeon

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 24

Background Despite the benefits from different options of therapy for breast cancer, resistance of the disease to these therapies is rising and a novel agent is needed. Erythro-austrobailignan-6 (EA6) exhibits anti-cancer activity. However, the detai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28443b200574acbbb9de44d8eaac03dc
https://pubmed.ncbi.nlm.nih.gov/28160858