Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Seongkyun Lim"'
Autor:
Francielly Morena da Silva, Seongkyun Lim, Ana Regina Cabrera, Eleanor R. Schrems, Ronald G. Jones, Megan E. Rosa-Caldwell, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Cancer-cachexia (CC) is a debilitating condition affecting up to 80% of cancer patients and contributing to 40% of cancer-related deaths. While evidence suggests biological sex differences in the development of CC, assessments of
Externí odkaz:
https://doaj.org/article/86945ba11d6a4815ac99fbe373b86a8f
Autor:
Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 2056-2068 (2021)
Abstract Background Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse‐induced muscle atrophy. Little data exist on early mechanisms cont
Externí odkaz:
https://doaj.org/article/c078e7da58e44ab58e7d90e1f6efbd14
Autor:
Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley A. Haynie, Jacob L. Brown, John William Deaver, Francielly Morena Da Silva, Lisa T. Jansen, David E. Lee, Michael P. Wiggs, Tyrone A. Washington, Nicholas P. Greene
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 3, Pp 717-730 (2021)
Abstract Background Muscle atrophy is a common pathology associated with disuse, such as prolonged bed rest or spaceflight, and is associated with detrimental health outcomes. There is emerging evidence that disuse atrophy may differentially affect m
Externí odkaz:
https://doaj.org/article/700d34c0af274608a96bc412768a4479
Publikováno v:
Sports Medicine and Health Science, Vol 2, Iss 4, Pp 177-185 (2020)
Cancer cachexia (CC) is a devastating syndrome characterized by weight loss, reduced fat mass and muscle mass that affects approximately 80% of cancer patients and is responsible for 22%–30% of cancer-associated deaths. Understanding underlying mec
Externí odkaz:
https://doaj.org/article/90957d7a97bd47708ca3a0992c4f9012
Autor:
Megan E. Rosa-Caldwell, Lisa T. Jansen, Seongkyun Lim, Kirsten R. Dunlap, Wesley S. Haynie, Tyrone A. Washington, Nicholas P. Greene
Publikováno v:
Sports Medicine and Health Science, Vol 2, Iss 1, Pp 44-53 (2020)
Exercise mitigates obesity-associated pathologies; however, there is controversy regarding optimal exercise interventions. Autophagy, is known to decrease during obesity and is an important moderator for exercise adaptations. Purpose: To investigate
Externí odkaz:
https://doaj.org/article/befba938ec6c492db9461ce51b44e17d
Autor:
Seongkyun Lim, Kirsten R. Dunlap, Megan E. Rosa‐Caldwell, Wesley S. Haynie, Lisa T. Jansen, Tyrone A. Washington, Nicholas P. Greene
Publikováno v:
Physiological Reports, Vol 8, Iss 19, Pp n/a-n/a (2020)
Abstract Skeletal muscle atrophy is common across a variety of pathologies. Underlying mechanisms of atrophy differ between pathologies, and in many conditions, circulating factors are tied to muscle atrophy. Therefore, we sought to identify alterati
Externí odkaz:
https://doaj.org/article/ee8eb363344245048f1e490c3f7923b6
Autor:
Seongkyun Lim, David E. Lee, Francielly Morena da Silva, Pieter J. Koopmans, Ivan J. Vechetti, Ferdinand von Walden, Nicholas P. Greene, Kevin A. Murach
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C1101-C1109
MicroRNAs (miRs) control stem cell biology and fate. Ubiquitously expressed and conserved miR-16 was the first miR implicated in tumorigenesis. miR-16 is low in muscle during developmental hypertrophy and regeneration. It is enriched in proliferating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c635bb5d3a8df2bb316fe4a5c50136b1
https://doi.org/10.1152/ajpcell.00071.2023
https://doi.org/10.1152/ajpcell.00071.2023
Autor:
Ronald G. Jones, Andrea Dimet‐Wiley, Amin Haghani, Francielly Morena da Silva, Camille R. Brightwell, Seongkyun Lim, Sabin Khadgi, Yuan Wen, Cory M. Dungan, Robert T. Brooke, Nicholas P. Greene, Charlotte A. Peterson, John J. McCarthy, Steve Horvath, Stanley J. Watowich, Christopher S. Fry, Kevin A. Murach
Publikováno v:
The Journal of Physiology. 601:763-782
Advances in the last decade related to cellular epigenetic reprogramming (e.g. DNA methylome remodeling) toward a pluripotent state via the Yamanaka transcription factors Oct3/4, Klf4, Sox2, and Myc (OKSM) provide a window into potential mechanisms f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d8192b7fe90ddf4aceec3140e5b7e7
https://doi.org/10.1113/jp283836
https://doi.org/10.1113/jp283836
Autor:
Tyrone A. Washington, Eleanor R. Schrems, Wesley S. Haynie, Megan E. Rosa‐Caldwell, Jacob L. Brown, Landen Saling, Seongkyun Lim, Richard A. Perry, Lemuel A. Brown, David E. Lee, Nicholas P. Greene
Publikováno v:
Cell Biochemistry and Function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de9218be45c1ec5f32784042d8b8bd64
https://doi.org/10.1002/cbf.3797
https://doi.org/10.1002/cbf.3797
Autor:
Ronald Jones, Andrea Dimet-Wiley, Amin Haghani, Francielly Morena da Silva, Camille Brightwell, Seongkyun Lim, Sabin Khadgi, Yuan Wen, Cory Dungan, Robert Brooke, Nicholas Greene, Charlotte Peterson, John McCarthy, Steve Horvath, Stanley Watowich, Christopher Fry, Kevin Murach
Publikováno v:
Physiology. 38
The objectives of this study were to measure to what extent exercise stimulates partial molecular reprogramming in skeletal muscle. We hypothesized that exercise training, beyond its known functional improvements in aged tissues, could recapitulate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c92e247aa7e27450aa677847e78edf
https://doi.org/10.1152/physiol.2023.38.s1.5733664
https://doi.org/10.1152/physiol.2023.38.s1.5733664