Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Seong-Keun Sonn"'
Autor:
Tae Kyeong Kim, Sejin Jeon, Seonjun Park, Seong-Keun Sonn, Seungwoon Seo, Joowon Suh, Jing Jin, Hyae Yon Kweon, Sinai Kim, Shin Hye Moon, Okhee Kweon, Bon-Hyeock Koo, Nayoung Kim, Hae-Ock Lee, Young-Myeong Kim, Young-Joon Kim, Sung Ho Park, Goo Taeg Oh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Maintaining optimal eNOS levels is important during cardiovascular events, although little is known regarding the mechanism of eNOS protection. Here, the authors show a regulatory role of endothelial OASL1 in maintaining eNOS mRNA stability and vascu
Externí odkaz:
https://doaj.org/article/40c92b716381415c80e90e99dcd018a0
Autor:
Sinai Kim, Wonhyo Lee, Huiju Jo, Seong-Keun Sonn, Se-Jin Jeong, Seungwoon Seo, Joowon Suh, Jing Jin, Hyae Yon Kweon, Tae Kyeong Kim, Shin Hye Moon, Sejin Jeon, Jong Woo Kim, Yu Ri Kim, Eun-Woo Lee, Hwa Kyoung Shin, Sung Ho Park, Goo Taeg Oh
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102347- (2022)
Ischemic stroke is the leading cause of immortal disability and death worldwide. For treatment in the acute phase, it is necessary to control excessive reactive oxygen species (ROS) damage during ischemia/reperfusion (I/R). Microglia are well known t
Externí odkaz:
https://doaj.org/article/eab751e3d206434187639c15f4153fba
Autor:
Hyae Yon Kweon, Mi-Ni Lee, Max Dorfel, Seungwoon Seo, Leah Gottlieb, Thomas PaPazyan, Nina McTiernan, Rasmus Ree, David Bolton, Andrew Garcia, Michael Flory, Jonathan Crain, Alison Sebold, Scott Lyons, Ahmed Ismail, Elaine Marchi, Seong-keun Sonn, Se-Jin Jeong, Sejin Jeon, Shinyeong Ju, Simon J Conway, Taesoo Kim, Hyun-Seok Kim, Cheolju Lee, Tae-Young Roh, Thomas Arnesen, Ronen Marmorstein, Goo Taeg Oh, Gholson J Lyon
Publikováno v:
eLife, Vol 10 (2021)
Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major acetyltransferase, with 40–50% of all mammalian proteins being potential substrates. Howeve
Externí odkaz:
https://doaj.org/article/d85446a69857408ca85b40a4aca5a127
Autor:
Jing Jin, In-Hyuk Jung, Shin Hye Moon, Sejin Jeon, Se-Jin Jeong, Seong-Keun Sonn, Seungwoon Seo, Mi-Ni Lee, Eun Ju Song, Hyae Yon Kweon, Sinai Kim, Tae Kyeong Kim, Juyang Kim, Hong Rae Cho, Jae-Hoon Choi, Byungsuk Kwon, Goo Taeg Oh
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4124-4136.e5 (2020)
Summary: CD137, a potent costimulatory receptor for CD8+ T cells, is expressed in various non-T cells, but little is known about its regulatory functions in these cells. In this study, we show that CD137 signaling, specifically in intestinal CD11b−
Externí odkaz:
https://doaj.org/article/b3c398b186994245969e3a371b486a34
Autor:
Sin Ri Kim, Ji Won Park, You-Jin Choi, Seong Keun Sonn, Goo Taeg Oh, Byung-Hoon Lee, Tong-Shin Chang
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 17 (2023)
Nonsteroidal anti-inflammatory drug (NSAID) use is associated with adverse consequences, including hepatic injury. The detrimental hepatotoxicity of diclofenac, a widely used NSAID, is primarily connected to oxidative damage in mitochondria, which ar
Externí odkaz:
https://doaj.org/article/65d057b83abc44c9afb34d6495c73d8c
Autor:
Seong Keun Sonn, Eun Ju Song, Seungwoon Seo, Young Yeon Kim, Jee-Hyun Um, Franklin Joonyeop Yeo, Da Seul Lee, Sejin Jeon, Mi-Ni Lee, Jing Jin, Hyae Yon Kweon, Tae Kyeong Kim, Sinai Kim, Shin Hye Moon, Sue Goo Rhee, Jongkyeong Chung, Jaemoon Yang, Jin Han, Eui-Young Choi, Sung Bae Lee, Jeanho Yun, Goo Taeg Oh
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102275- (2022)
Mitochondrial quality control (MQC) consists of multiple processes: the prevention of mitochondrial oxidative damage, the elimination of damaged mitochondria via mitophagy and mitochondrial fusion and fission. Several studies proved that MQC impairme
Externí odkaz:
https://doaj.org/article/b06c28f81d344d92b4d31826df3188a6
Autor:
Kihyoun Park, Seong Keun Sonn, Seungwoon Seo, Jinyoung Kim, Kyu Yeon Hur, Goo Taeg Oh, Myung-Shik Lee
Publikováno v:
Autophagy.
Macroautophagy/autophagy or mitophagy plays crucial roles in the maintenance of pancreatic β-cell function. PPP3/calcineurin can modulate the activity of TFEB, a master regulator of lysosomal biogenesis and autophagy gene expression, through dephosp
Autor:
Kyu-Won Kim, Tae-Young Roh, Dahee Shim, Nayoung K.D. Kim, Jae-Hoon Choi, Tae Kyeong Kim, Jing Jin, Woong-Yang Park, Sejin Jeon, Sang Hak Lee, Seungwoon Seo, Mi Ni Lee, Young Mi Park, Sinai Kim, Se Jin Jeong, Hyunbo Shim, In Hyuk Jung, Sung Ho Park, Myron I. Cybulsky, Goo Taeg Oh, Hae Ock Lee, Hyae Yon Kweon, Seong Keun Sonn
Publikováno v:
Circulation. 142:1736-1751
Background: Macrophages produce many inflammation-associated molecules, released by matrix metalloproteinases, such as adhesion molecules, and cytokines, as well, which play a crucial role in atherosclerosis. In this context, we investigated the rela
Autor:
Sejin Jeon, Shin Hye Moon, Juyang Kim, Mi Ni Lee, Byungsuk Kwon, Se Jin Jeong, Eun Ju Song, Goo Taeg Oh, Tae Kyeong Kim, Hyae Yon Kweon, Sinai Kim, Seungwoon Seo, Seong Keun Sonn, Jae-Hoon Choi, Jing Jin, In Hyuk Jung, Hong Rae Cho
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4124-4136.e5 (2020)
Summary: CD137, a potent costimulatory receptor for CD8+ T cells, is expressed in various non-T cells, but little is known about its regulatory functions in these cells. In this study, we show that CD137 signaling, specifically in intestinal CD11b−
Autor:
Tae Kyeong Kim, Sejin Jeon, Seonjun Park, Seong-Keun Sonn, Seungwoon Seo, Joowon Suh, Jing Jin, Hyae Yon Kweon, Sinai Kim, Shin Hye Moon, Okhee Kweon, Bon-Hyeock Koo, Nayoung Kim, Hae-Ock Lee, Young-Myeong Kim, Young-Joon Kim, Sung Ho Park, Goo Taeg Oh
Publikováno v:
Nature communications. 13(1)
Endothelial nitric oxide synthase (eNOS) decreases following inflammatory stimulation. As a master regulator of endothelial homeostasis, maintaining optimal eNOS levels is important during cardiovascular events. However, little is known regarding the