Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Seong-Ah Shin"'
Autor:
Minji Kim, Jangeun An, Seong-Ah Shin, Sun Young Moon, Moonsu Kim, Seyeon Choi, Huiji Kim, Kim-Hoa Phi, Jun Hyuck Lee, Ui Joung Youn, Hyun Ho Park, Chang Sup Lee
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-12 (2024)
Abstract Inflammation is an essential defense mechanism in health; however, excessive inflammation contributes to the pathophysiology of several chronic diseases. Although anti-inflammatory drugs are essential for controlling inflammation, they have
Externí odkaz:
https://doaj.org/article/d03bc242df134b0aa21a2f4d2768f959
Autor:
Seyeon Choi, Huiji Kim, Seong-Ah Shin, Moonsu Kim, Sun Young Moon, Minji Kim, Seulah Lee, Jun Hyuck Lee, Hyun Ho Park, Ui Joung Youn, Chang Sup Lee
Publikováno v:
Applied Biological Chemistry, Vol 66, Iss 1, Pp 1-10 (2023)
Abstract Malignant melanoma is a fatal disease with an increasing global incidence. Despite numerous studies focused on anti-cancer drugs, a variety of side effects of cancer treatment remain challenging. Thus, there is a pressing need to identify no
Externí odkaz:
https://doaj.org/article/2b55514c05d34dc9937fe36a49731aab
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 48 (2023)
The development of drugs targeting the central nervous system (CNS) is challenging because of the presence of the Blood-Brain barrier (BBB). Developing physiologically relevant in vitro BBB models for evaluating drug permeability and predicting the a
Externí odkaz:
https://doaj.org/article/47d6ae52940f43e99bf11189c39cd01c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15072 (2023)
Cancer immunotherapy strategies are based on the utilization of immune checkpoint inhibitors to instigate an antitumor immune response. The efficacy of immune checkpoint blockade, directed at adaptive immune checkpoints, has been demonstrated in sele
Externí odkaz:
https://doaj.org/article/324c7460b26e42b4b1e049800ca54ccf
Autor:
Jangeun An, Gyoungah Ryu, Seong-Ah Shin, Huiji Kim, Mi-Jeong Ahn, Jun Hyuck Lee, Chang Sup Lee
Publikováno v:
Molecules, Vol 27, Iss 17, p 5719 (2022)
Inflammation is an immune response to cellular damage caused by various stimuli (internal or external) and is essential to human health. However, excessive inflammatory responses may be detrimental to the host. Considering that the existing drugs for
Externí odkaz:
https://doaj.org/article/2c00edea5d604c7abca63c27e73aab45
Autor:
Minjoo Han, Gyoungah Ryu, Seong-Ah Shin, Jangeun An, Huiji Kim, Daeho Park, Dae-Hee Lee, Chang Sup Lee
Publikováno v:
Life, Vol 11, Iss 11, p 1141 (2021)
The clearance of apoptotic cells is known to be a critical step in maintaining tissue and organism homeostasis. This process is rapidly/promptly mediated by recruited or resident phagocytes. Phagocytes that engulf apoptotic cells have been closely li
Externí odkaz:
https://doaj.org/article/2a25e3e33ba34f02a2a00f6e7a9c260d
Publikováno v:
Genes, Vol 9, Iss 12, p 597 (2018)
Brain-specific angiogenesis inhibitors (BAIs) 1, 2, and 3 are members of the adhesion G protein-coupled receptors, subfamily B, which share a conserved seven-transmembrane structure and an N-terminal extracellular domain. In cell- and animal-based st
Externí odkaz:
https://doaj.org/article/0ebffaeed25747bea6e15b4d56740bb3
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2651 (2018)
A variety of malignant cancers affect the global human population. Although a wide variety of approaches to cancer treatment have been studied and used clinically (surgery, radiotherapy, chemotherapy, and immunotherapy), the toxic side effects of can
Externí odkaz:
https://doaj.org/article/6344e5a71b5240479626ff496712e2d8
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 275 (2017)
Ixeris dentata (Thunb. Ex Thunb.) Nakai (ID) exhibits various physiological activities, and its related plant derived-products are expected to represent promising cancer therapeutic agents. However, the anticancer effects of ID extract on breast canc
Externí odkaz:
https://doaj.org/article/73e32802ed6640fb868fad7c9efe6156
Publikováno v:
Marine Drugs, Vol 14, Iss 7, p 126 (2016)
In this study, we showed that PI3K/Akt signaling mediates fucoidan’s anticancer effects on prostate cancer cells, including suppression of proliferation. Fucoidan significantly decreased viability of DU-145 cancer cells in a concentration-dependent
Externí odkaz:
https://doaj.org/article/d50ba1b8e0e64ce6a246d819c2b85301