Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Seong S. Shim"'
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-29 (2023)
Abstract Stroke and late-onset Alzheimer’s disease (AD) are risk factors for each other; the comorbidity of these brain disorders in aging individuals represents a significant challenge in basic research and clinical practice. The similarities and
Externí odkaz:
https://doaj.org/article/e1512064a32a46c7a8810611d864651b
Autor:
Alyssa L, Wiseman, Clark A, Briggs, Ariel, Peritt, Nicolas, Kapecki, Daniel A, Peterson, Seong S, Shim, Grace E, Stutzmann
Publikováno v:
Journal of Alzheimer's Disease. 91:273-290
Background: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder with a progressive loss of cognitive function. Currently, no effective treatment regimen is available. Lithium, a mood stabilizer for bipolar disorder, exerts broad neurop
Publikováno v:
Schizophrenia Research. 170:226-231
Schizophrenia is a progressive psychotic disorder with devastating effects on the broad aspects of human emotion, perception, thought, and psychosocial interactions. Although treatment with antipsychotic drugs, the mainstay in the treatment of schizo
Publikováno v:
Biological Psychiatry. 83:S347-S348
Publikováno v:
Alzheimer's & Dementia. 15:P306-P306
Autor:
Seong S. Shim, Grace E. Stutzmann
Publikováno v:
Journal of neurotrauma. 33(23)
Although traumatic brain injury (TBI) has been a major public health concern for decades, the pathophysiological mechanism of TBI is not clearly understood, and an effective medical treatment of TBI is not available at present. Of particular concern
Publikováno v:
Neuroscience Letters. 524:5-9
Neuroplastic theories propose that lithium has robust neuroprotective and neurotrophic actions leading to the up-regulation of synaptic plasticity, and this action may be associated with the efficacy of lithium in the treatment of bipolar disorder. O
Autor:
Seong S. Shim, Michael D. Hammonds
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 105:113-119
A large body of evidence indicates that lithium, the prototype mood stabilizer in the treatment of bipolar disorder, has diverse neuroprotective and neurotrophic actions, and the actions are associated with its efficacy in treating bipolar disorder.
Autor:
Joseph R. Calabrese, Bryan K. Tolliver, Kathleen T. Brady, Seong S. Shim, Robert L. Findling, Stephen J. Ganocy, David E. Kemp, Keming Gao, Sarah Bilali, Marcia L. Verduin
Publikováno v:
Journal of Affective Disorders. 110:167-173
Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions.Extensive clinical interview and MINI were used to ascertain DSM-IV diagnoses of
Publikováno v:
Neuroscience. 150:774-788
Recent electrophysiological work shows that chronic lithium treatment increases long-term potentiation (LTP) in neurons of the hippocampus, and LTP is thought to be the major neurophysiological basis for the development of learning and memory. This s