Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Seong Kwon Hur"'
Autor:
Seong Kwon Hur, Mandana Hunter, Myrna A. Dominique, Madona Farag, Dejania Cotton-Samuel, Tahiyana Khan, John Q. Trojanowski, Krista J. Spiller, Virginia M.-Y. Lee
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract In the intermediate stages of amyotrophic lateral sclerosis (ALS), surviving motor neurons (MNs) that show intrinsic resistance to TDP-43 proteinopathy can partially compensate for the loss of their more disease-susceptible counterparts. Elu
Externí odkaz:
https://doaj.org/article/1b3b0b964de041b99491d6bba9c751fc
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Several studies investigating the pathogenesis of Alzheimer’s disease have identified various interdependent constituents contributing to the exacerbation of the disease, including Aβ plaque formation, tau protein hyperphosphorylation, neurofibril
Externí odkaz:
https://doaj.org/article/6d317899ec664ddea3f0a3b1c1ed3840
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 991-999 (2016)
Summary: Inborn errors of metabolism (IEMs) occur with high incidence in human populations. Especially prevalent among these are inborn deficiencies in fatty acid β-oxidation (FAO), which are clinically associated with developmental neuropsychiatric
Externí odkaz:
https://doaj.org/article/677d4391706e432687a66dd2704b9214
Autor:
Chwee Tat Koe, Ye Sing Tan, Max Lönnfors, Seong Kwon Hur, Christine Siok Lan Low, Yingjie Zhang, Pakorn Kanchanawong, Vytas A Bankaitis, Hongyan Wang
Publikováno v:
eLife, Vol 7 (2018)
A central feature of most stem cells is the ability to self-renew and undergo differentiation via asymmetric division. However, during asymmetric division the role of phosphatidylinositol (PI) lipids and their regulators is not well established. Here
Externí odkaz:
https://doaj.org/article/f89c1270291546408dfdbcb38f7cbefd
Publikováno v:
Frontiers in Neuroscience; 11/4/2022, Vol. 16, p1-31, 31p
Publikováno v:
Chemical Communications. 54:9031-9034
SN-38 (7-ethyl-10-hydroxy-camptothecin) is an active metabolite of irinotecan (CPT-11) and the most potent camptothecin analogue. In this study, 2,4-dinitrobenzene sulfonyl (DNS) was covalently conjugated as a GSH-sensitive trigger to 10'-OH of SN-38
Autor:
Ramiro Diz, Mark I. McDermott, Aby Grabon, Banafshé Larijani, Christopher J. Applebee, Marta G. Lete, Seong Kwon Hur, Ashutosh Tripathi, Michael J.O. Wakelam, Vytas A. Bankaitis
Publikováno v:
The FASEB Journal. 33
Autor:
Seong Kwon Hur, Chwee Tat Koe, Pakorn Kanchanawong, Ye Sing Tan, Christine Siok Lan Low, Hongyan Wang, Vytas A. Bankaitis, Max Lönnfors, Yingjie Zhang
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
A central feature of most stem cells is the ability to self-renew and undergo differentiation via asymmetric division. However, during asymmetric division the role of phosphatidylinositol (PI) lipids and their regulators is not well established. Here
Autor:
Pakorn Kanchanawong, Yingjie Zhang, Vytas A. Bankaitis, Max Lönnfors, Seong Kwon Hur, Ye Sing Tan, Chwee Tat Koe, Christine Siok Lan Low, Hongyan Wang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bdf9a714b8207d6c7e5adf7da7b1ec3
https://doi.org/10.7554/elife.33555.026
https://doi.org/10.7554/elife.33555.026
Publikováno v:
Developmental Cell. 44:725-740.e4
Summary Phosphatidylinositol (PtdIns) transfer proteins (PITPs) stimulate PtdIns-4-P synthesis and signaling in eukaryotic cells, but to what biological outcomes such signaling circuits are coupled remains unclear. Herein, we show that two highly rel